CA2477218A1 - Derives de propargylaminoindane et derives de propargylaminotetraline utilises comme inhibiteurs de la mao cerebro-selectifs - Google Patents
Derives de propargylaminoindane et derives de propargylaminotetraline utilises comme inhibiteurs de la mao cerebro-selectifs Download PDFInfo
- Publication number
- CA2477218A1 CA2477218A1 CA002477218A CA2477218A CA2477218A1 CA 2477218 A1 CA2477218 A1 CA 2477218A1 CA 002477218 A CA002477218 A CA 002477218A CA 2477218 A CA2477218 A CA 2477218A CA 2477218 A1 CA2477218 A1 CA 2477218A1
- Authority
- CA
- Canada
- Prior art keywords
- compound
- alkyl
- salt
- reacting
- aralkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8567402A | 2002-02-27 | 2002-02-27 | |
| US10/085,674 | 2002-02-27 | ||
| PCT/US2003/005871 WO2003072055A2 (fr) | 2002-02-27 | 2003-02-27 | Derives de propargylaminoindane et derives de propargylaminotetraline utilises comme inhibiteurs de la mao cerebro-selectifs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2477218A1 true CA2477218A1 (fr) | 2003-09-04 |
Family
ID=27765338
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002477218A Abandoned CA2477218A1 (fr) | 2002-02-27 | 2003-02-27 | Derives de propargylaminoindane et derives de propargylaminotetraline utilises comme inhibiteurs de la mao cerebro-selectifs |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1490324A4 (fr) |
| JP (1) | JP2005523289A (fr) |
| AU (1) | AU2003219913A1 (fr) |
| CA (1) | CA2477218A1 (fr) |
| WO (1) | WO2003072055A2 (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1567152B1 (fr) | 2002-11-15 | 2013-08-14 | Teva Pharmaceutical Industries Limited | Utilisation de la rasagiline avec du riluzole pour traiter la sclerose laterale amyotrophique |
| CA2901244A1 (fr) | 2005-02-23 | 2006-08-31 | Teva Pharmaceutical Industries, Ltd. | Preparations de rasagiline presentant une uniformite de teneur amelioree |
| EP1848417A1 (fr) | 2005-02-24 | 2007-10-31 | Teva Pharmaceutical Industries Ltd | Preparations de tartrate de ladostigil |
| AU2006252540B2 (en) | 2005-06-02 | 2011-12-01 | Jenrin Discovery | MAO-B inhibitors useful for treating obesity |
| EP1906952A4 (fr) | 2005-07-01 | 2010-04-14 | Jenrin Discovery | Inhibiteurs mao-b utiles dans le traitement de l obésité |
| JP2009521402A (ja) * | 2005-11-17 | 2009-06-04 | テバ ファーマシューティカル インダストリーズ リミティド | プロパルギル化アミノインダンの分離のための方法 |
| US7572834B1 (en) | 2005-12-06 | 2009-08-11 | Teva Pharmaceutical Industries, Ltd. | Rasagiline formulations and processes for their preparation |
| TW200744576A (en) | 2006-02-24 | 2007-12-16 | Teva Pharma | Propargylated aminoindans, processes for preparation, and uses thereof |
| EP2007369A4 (fr) | 2006-04-03 | 2009-07-01 | Teva Pharma | Utilisation de rasagiline pour le traitement du syndrome des jambes sans repos |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1187017A (en) * | 1966-07-16 | 1970-04-08 | Aspro Nicholas Ltd | Substituted 1-Amino Indanes and Tetrahydronaphthalens |
| SE9103745D0 (sv) * | 1991-12-18 | 1991-12-18 | Wikstroem Haakan | Aryl-triflates and related compounds |
| WO1994022495A1 (fr) * | 1993-03-31 | 1994-10-13 | The Trustees Of The University Of Pennsylvania | Ligands de recepteurs de la dopamine d-3 et de la serotonine (5-ht1a) et agents d'imagerie |
| EP0738149B1 (fr) * | 1994-01-10 | 2006-11-29 | Teva Pharmaceutical Industries, Ltd. | Derives de 1-amino-indane et leurs compositions |
| WO1996036596A1 (fr) * | 1995-05-19 | 1996-11-21 | Chiroscience Limited | 3,4-phenylsulfamides disubstitues et leur utilisation therapeutique |
| EP0882046A1 (fr) * | 1996-02-21 | 1998-12-09 | Darwin Discovery Limited | Quinolones et leur utilisation therapeutique |
| DE69738275T2 (de) * | 1996-12-18 | 2008-08-28 | Teva Pharmaceutical Industries Ltd. | Aminoindanderivate |
-
2003
- 2003-02-27 JP JP2003570802A patent/JP2005523289A/ja active Pending
- 2003-02-27 WO PCT/US2003/005871 patent/WO2003072055A2/fr not_active Ceased
- 2003-02-27 AU AU2003219913A patent/AU2003219913A1/en not_active Abandoned
- 2003-02-27 CA CA002477218A patent/CA2477218A1/fr not_active Abandoned
- 2003-02-27 EP EP03716197A patent/EP1490324A4/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP1490324A2 (fr) | 2004-12-29 |
| AU2003219913A1 (en) | 2003-09-09 |
| AU2003219913A8 (en) | 2003-09-09 |
| WO2003072055A2 (fr) | 2003-09-04 |
| WO2003072055A3 (fr) | 2003-12-31 |
| JP2005523289A (ja) | 2005-08-04 |
| EP1490324A4 (fr) | 2007-10-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Dead |