CA2478902A1 - Methodes de traitement de troubles des glandes mammaires - Google Patents
Methodes de traitement de troubles des glandes mammaires Download PDFInfo
- Publication number
- CA2478902A1 CA2478902A1 CA002478902A CA2478902A CA2478902A1 CA 2478902 A1 CA2478902 A1 CA 2478902A1 CA 002478902 A CA002478902 A CA 002478902A CA 2478902 A CA2478902 A CA 2478902A CA 2478902 A1 CA2478902 A1 CA 2478902A1
- Authority
- CA
- Canada
- Prior art keywords
- mammary gland
- botulinum toxin
- treating
- local administration
- disorder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000005075 mammary gland Anatomy 0.000 title claims abstract 19
- 238000000034 method Methods 0.000 title claims abstract 15
- 108030001720 Bontoxilysin Proteins 0.000 claims abstract 9
- 229940053031 botulinum toxin Drugs 0.000 claims abstract 7
- 210000000481 breast Anatomy 0.000 claims abstract 3
- 230000001613 neoplastic effect Effects 0.000 claims abstract 3
- 210000001519 tissue Anatomy 0.000 claims abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 7
- 208000035475 disorder Diseases 0.000 claims 7
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 231100001103 botulinum neurotoxin Toxicity 0.000 claims 2
- 208000035269 cancer or benign tumor Diseases 0.000 claims 2
- 206010020718 hyperplasia Diseases 0.000 claims 2
- 230000002390 hyperplastic effect Effects 0.000 claims 2
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 206010006220 Breast cyst Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 208000000571 Fibrocystic breast disease Diseases 0.000 claims 1
- 108010057266 Type A Botulinum Toxins Proteins 0.000 claims 1
- 201000008997 blunt duct adenosis of breast Diseases 0.000 claims 1
- 229940094657 botulinum toxin type a Drugs 0.000 claims 1
- 201000003161 breast duct papilloma Diseases 0.000 claims 1
- 201000003149 breast fibroadenoma Diseases 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 239000007943 implant Substances 0.000 claims 1
- 238000002513 implantation Methods 0.000 claims 1
- 208000035803 proliferative type breast fibrocystic change Diseases 0.000 claims 1
- 201000008662 sclerosing adenosis of breast Diseases 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
- A61K38/4893—Botulinum neurotoxin (3.4.24.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Processing Of Meat And Fish (AREA)
- Steroid Compounds (AREA)
- Peptides Or Proteins (AREA)
- Jellies, Jams, And Syrups (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/071,826 US7838007B2 (en) | 1999-12-07 | 2002-02-08 | Methods for treating mammary gland disorders |
| US10/071,826 | 2002-02-08 | ||
| PCT/US2003/003479 WO2004071525A1 (fr) | 2002-02-08 | 2003-02-04 | Methodes de traitement de troubles des glandes mammaires |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2478902A1 true CA2478902A1 (fr) | 2004-08-26 |
| CA2478902C CA2478902C (fr) | 2012-05-01 |
Family
ID=32867445
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2478902A Expired - Fee Related CA2478902C (fr) | 2002-02-08 | 2003-02-04 | Methodes de traitement de troubles des glandes mammaires |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US7838007B2 (fr) |
| EP (3) | EP2204183A1 (fr) |
| JP (2) | JP4889220B2 (fr) |
| AT (1) | ATE331527T1 (fr) |
| AU (1) | AU2003225549B2 (fr) |
| BR (1) | BR0307496A (fr) |
| CA (1) | CA2478902C (fr) |
| DE (1) | DE60306505T2 (fr) |
| DK (1) | DK1492561T3 (fr) |
| ES (1) | ES2264041T3 (fr) |
| PT (1) | PT1492561E (fr) |
| WO (1) | WO2004071525A1 (fr) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7838008B2 (en) * | 1999-12-07 | 2010-11-23 | Allergan, Inc. | Methods for treating diverse cancers |
| US7838007B2 (en) * | 1999-12-07 | 2010-11-23 | Allergan, Inc. | Methods for treating mammary gland disorders |
| AU2001270219A1 (en) * | 2000-06-28 | 2002-01-08 | Ira Sanders | Methods for using tetanus toxin for benificial purposes in animals (mammals) |
| US20120114697A1 (en) * | 2002-08-19 | 2012-05-10 | Ira Sanders | Treatment of holocrine gland dysfunction with clostridia neurotoxins |
| US7824693B2 (en) | 2002-08-19 | 2010-11-02 | Ira Sanders | Treatment of fine wrinkles with clostridia neurotoxins |
| EP2272340B1 (fr) | 2002-08-19 | 2018-03-14 | Ira Sanders | Toxine botulique |
| WO2004066928A2 (fr) * | 2003-01-24 | 2004-08-12 | Albert Einstein College Of Medicine Of Yeshiva University | Utilisation de vaccins a mycobacteries chez des mammiferes presentant une deficience en lymphocytes cd4+ et/ou cd8+. |
| AU2004238289A1 (en) * | 2003-05-09 | 2004-11-25 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treating cancer |
| US8048423B2 (en) * | 2003-12-09 | 2011-11-01 | Allergan, Inc. | Botulinum toxin therapy for skin disorders |
| US8871224B2 (en) | 2003-12-09 | 2014-10-28 | Allergan, Inc. | Botulinum toxin therapy for skin disorders |
| US20050220734A1 (en) * | 2004-04-02 | 2005-10-06 | Allergan, Inc. | Therapy for melanin related afflictions |
| US20070258900A1 (en) * | 2004-07-20 | 2007-11-08 | Joseph Francis | Blood Flow Assessment of Clostridial Toxin Applications |
| EP1778078A2 (fr) * | 2004-07-20 | 2007-05-02 | Allergan, Inc. | Evaluation thermographique d'applications de toxine clostridiale |
| US8343929B2 (en) * | 2004-09-23 | 2013-01-01 | Toxcure, Inc. | Treating neoplasms with neurotoxin |
| DK2168594T3 (en) * | 2004-09-23 | 2015-08-03 | Toxcure Inc | The treatment of neoplasms with neurotoxin |
| US20060073208A1 (en) * | 2004-10-01 | 2006-04-06 | Allergan, Inc. | Cosmetic neurotoxin compositions and methods |
| US8155408B2 (en) * | 2008-04-15 | 2012-04-10 | General Electric Company | Standardized normal database having anatomical phase information |
| AU2009319732B2 (en) | 2008-11-26 | 2013-09-05 | Toxcure, Inc. | Treating neoplasms with neurotoxin |
| US8629103B2 (en) | 2010-12-02 | 2014-01-14 | New York University | Treatment of non-proliferative cystic disease of the breast |
| WO2012097189A1 (fr) * | 2011-01-13 | 2012-07-19 | Rutgers, The State University Of New Jersey | Systèmes et procédés pour l'enregistrement multiprotocole et la classification de tissus utilisant une échelle morphologique locale |
| CA2841917A1 (fr) | 2011-07-14 | 2013-01-17 | Allergan, Inc. | Procedes pour le traitement de l'incontinence associee a l'activite sexuelle |
| EP2649984A1 (fr) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Composés qui inhibent l'exocytosis neuronale |
| EP2649985A1 (fr) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Composés inhibant l'exocytosis neuronale (III) |
| CA2869599C (fr) | 2012-04-13 | 2021-07-27 | Lubrizol Advanced Materials, Inc. | Composes inhibant l'exocytose neuronale (ii) |
| EP2649983A1 (fr) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Composés inhibant l'exocytosis neuronale (II) |
| US11191819B2 (en) | 2018-08-28 | 2021-12-07 | Ira Sanders | Skin therapeutics |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4664911A (en) | 1983-06-21 | 1987-05-12 | Board Of Regents, University Of Texas System | Immunotoxin conjugates employing toxin B chain moieties |
| US5183462A (en) | 1990-08-21 | 1993-02-02 | Associated Synapse Biologics | Controlled administration of chemodenervating pharmaceuticals |
| US5466672A (en) | 1992-12-04 | 1995-11-14 | Ophidian Pharmaceuticals, Inc. | Therapeutic use of clostridium difficile toxin A |
| US5437291A (en) | 1993-08-26 | 1995-08-01 | Univ Johns Hopkins | Method for treating gastrointestinal muscle disorders and other smooth muscle dysfunction |
| US6974578B1 (en) * | 1993-12-28 | 2005-12-13 | Allergan, Inc. | Method for treating secretions and glands using botulinum toxin |
| US5766605A (en) | 1994-04-15 | 1998-06-16 | Mount Sinai School Of Medicine Of The City University Of New York | Treatment of autonomic nerve dysfunction with botulinum toxin |
| US5670484A (en) | 1994-05-09 | 1997-09-23 | Binder; William J. | Method for treatment of skin lesions associated with cutaneous cell-proliferative disorders |
| EP0758900B1 (fr) | 1994-05-09 | 2002-04-10 | BINDER, William J. | Toxine de Botulinum pour la REDUCTION DES CEPHALEES DE LA MIGRAINE |
| US5595740A (en) | 1994-05-16 | 1997-01-21 | University Of Florida | Cloning of non-IgA FC binding forms of the group B streptococcal beta antigens |
| GB9508204D0 (en) | 1995-04-21 | 1995-06-07 | Speywood Lab Ltd | A novel agent able to modify peripheral afferent function |
| US6143037A (en) * | 1996-06-12 | 2000-11-07 | The Regents Of The University Of Michigan | Compositions and methods for coating medical devices |
| GB9617671D0 (en) | 1996-08-23 | 1996-10-02 | Microbiological Res Authority | Recombinant toxin fragments |
| KR100544060B1 (ko) * | 1997-07-15 | 2006-01-23 | 더 리젠트스 오브 더 유니버시티 오브 콜로라도 | 비뇨기과학 및 관련 부전증을 치료하기 위한 신경독요법의 용도 |
| US6063768A (en) | 1997-09-04 | 2000-05-16 | First; Eric R. | Application of botulinum toxin to the management of neurogenic inflammatory disorders |
| GB9721189D0 (en) | 1997-10-08 | 1997-12-03 | Speywood Lab The Limited | Analgesic conjugates |
| DE19802569A1 (de) | 1998-01-23 | 1999-09-09 | Univ Albert Ludwigs Freiburg | Toxikologisch aktive Fragmente des lethalen Toxins von Clostridium sordellii und deren Verwendung in Immuntoxinen |
| GB9818548D0 (en) | 1998-08-25 | 1998-10-21 | Microbiological Res Authority | Treatment of mucas hypersecretion |
| TW574036B (en) | 1998-09-11 | 2004-02-01 | Elan Pharm Inc | Stable liquid compositions of botulinum toxin |
| WO2000024419A1 (fr) | 1998-10-27 | 2000-05-04 | Mayo Foundation For Medical Education And Research | Methodes visant a faciliter la cicatrisation d'une plaie |
| DE19852981A1 (de) | 1998-11-17 | 2000-05-18 | Martin Schmidt | Botulinum-Toxine, deren Derivate, Analoge und molekulare Bruchstücke zur topischen epicutanen Anwendung auch in Zusammenwirken mit hautpenetrationsfördernden Substanzen und Maßnahmen in Zubereitungsformen zur Beeinflussung acetylcholinabhängiger Körperfunktionen |
| DE19856052A1 (de) | 1998-12-04 | 2000-06-08 | Deutsches Krebsforsch | Konjugat zur Anreicherung in neuronalen Zellen |
| GB9907429D0 (en) | 1999-03-31 | 1999-05-26 | Microbiological Res Authority | Modulation of C-fibre activity |
| ES2320849T3 (es) | 1999-04-16 | 2009-05-29 | Marvin Schwartz | Procedimiento para reducir la perdida del cabello y estimular el crecimiento del mismo. |
| DE19925739A1 (de) | 1999-06-07 | 2000-12-21 | Biotecon Ges Fuer Biotechnologische Entwicklung & Consulting Mbh | Therapeutikum mit einem Botulinum-Neurotoxin |
| GB9922554D0 (en) | 1999-09-23 | 1999-11-24 | Microbiological Res Authority | Inhibition of secretion from non-neuronal cells |
| US6113915A (en) | 1999-10-12 | 2000-09-05 | Allergan Sales, Inc. | Methods for treating pain |
| US6265379B1 (en) | 1999-10-13 | 2001-07-24 | Allergan Sales, Inc. | Method for treating otic disorders |
| US6139845A (en) | 1999-12-07 | 2000-10-31 | Allergan Sales, Inc. | Method for treating cancer with a neurotoxin |
| US7838007B2 (en) * | 1999-12-07 | 2010-11-23 | Allergan, Inc. | Methods for treating mammary gland disorders |
| US6261572B1 (en) | 2000-01-11 | 2001-07-17 | Allergan Sales, Inc. | Method for treating a pancreatic disorder with a neurotoxin |
| US6143306A (en) | 2000-01-11 | 2000-11-07 | Allergan Sales, Inc. | Methods for treating pancreatic disorders |
| US6641820B1 (en) | 2000-01-19 | 2003-11-04 | Allergan, Inc. | Clostridial toxin derivatives and methods to treat pain |
| US6306423B1 (en) | 2000-06-02 | 2001-10-23 | Allergan Sales, Inc. | Neurotoxin implant |
| WO2002009743A1 (fr) | 2000-08-02 | 2002-02-07 | Allergan Sales, Inc. | Methode de traitement d'un neoplasme |
| US6831059B2 (en) | 2000-10-20 | 2004-12-14 | Allergan, Inc. | Compositions and methods for treating gonadotrophin related illnesses |
-
2002
- 2002-02-08 US US10/071,826 patent/US7838007B2/en not_active Expired - Fee Related
-
2003
- 2003-02-04 JP JP2004568252A patent/JP4889220B2/ja not_active Expired - Fee Related
- 2003-02-04 DK DK03815338T patent/DK1492561T3/da active
- 2003-02-04 ES ES03815338T patent/ES2264041T3/es not_active Expired - Lifetime
- 2003-02-04 BR BR0307496-0A patent/BR0307496A/pt not_active IP Right Cessation
- 2003-02-04 CA CA2478902A patent/CA2478902C/fr not_active Expired - Fee Related
- 2003-02-04 EP EP10156608A patent/EP2204183A1/fr not_active Ceased
- 2003-02-04 EP EP03815338A patent/EP1492561B1/fr not_active Expired - Lifetime
- 2003-02-04 AU AU2003225549A patent/AU2003225549B2/en not_active Ceased
- 2003-02-04 DE DE60306505T patent/DE60306505T2/de not_active Expired - Lifetime
- 2003-02-04 AT AT03815338T patent/ATE331527T1/de active
- 2003-02-04 PT PT03815338T patent/PT1492561E/pt unknown
- 2003-02-04 EP EP06005325A patent/EP1728517A3/fr not_active Ceased
- 2003-02-04 WO PCT/US2003/003479 patent/WO2004071525A1/fr not_active Ceased
-
2005
- 2005-07-29 US US11/192,777 patent/US7846456B2/en not_active Expired - Lifetime
-
2011
- 2011-10-18 JP JP2011228787A patent/JP2012025775A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003225549B2 (en) | 2006-11-16 |
| ATE331527T1 (de) | 2006-07-15 |
| EP2204183A1 (fr) | 2010-07-07 |
| JP2006510723A (ja) | 2006-03-30 |
| US20050260231A1 (en) | 2005-11-24 |
| DE60306505D1 (de) | 2006-08-10 |
| EP1728517A2 (fr) | 2006-12-06 |
| DK1492561T3 (da) | 2006-09-25 |
| US7846456B2 (en) | 2010-12-07 |
| DE60306505T2 (de) | 2007-01-11 |
| AU2003225549A1 (en) | 2004-09-06 |
| CA2478902C (fr) | 2012-05-01 |
| JP2012025775A (ja) | 2012-02-09 |
| US20020094339A1 (en) | 2002-07-18 |
| US7838007B2 (en) | 2010-11-23 |
| EP1728517A3 (fr) | 2008-06-25 |
| EP1492561B1 (fr) | 2006-06-28 |
| WO2004071525A1 (fr) | 2004-08-26 |
| JP4889220B2 (ja) | 2012-03-07 |
| ES2264041T3 (es) | 2006-12-16 |
| BR0307496A (pt) | 2005-06-28 |
| PT1492561E (pt) | 2006-10-31 |
| EP1492561A1 (fr) | 2005-01-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20150204 |