CA2492434A1 - Procede permettant d'accroitre et/ou d'induire une migration neuronale au moyen de l'erythropoietine - Google Patents
Procede permettant d'accroitre et/ou d'induire une migration neuronale au moyen de l'erythropoietine Download PDFInfo
- Publication number
- CA2492434A1 CA2492434A1 CA002492434A CA2492434A CA2492434A1 CA 2492434 A1 CA2492434 A1 CA 2492434A1 CA 002492434 A CA002492434 A CA 002492434A CA 2492434 A CA2492434 A CA 2492434A CA 2492434 A1 CA2492434 A1 CA 2492434A1
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- Prior art keywords
- neural stem
- growth factor
- multipotent neural
- erythropoietin
- stem cells
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1808—Epidermal growth factor [EGF] urogastrone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Zoology (AREA)
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- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
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- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
L'invention concerne des procédés permettant d'accroître et/ou d'induire une migration de cellules souches neurales ou de cellules progénitrices neuronales. Des cellules souches neurales multipotentes sont exposées à l'érythropoiétine accroissant la migration desdites cellules et des cellules progénitrices neuronales. L'érythropoiétine peut être appliquée de manière exogène sur les cellules souches neurales multipotentes ou, de manière alternative, les cellules peuvent être soumises à une agression hypoxique induisant l'expression de l'érythropoiétine par les cellules. Dans un mode de réalisation préféré, des facteurs de croissance supplémentaires, tels que le facteur de croissance de l'épiderme (EGF) et la prolactine, sont utilisés.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39939502P | 2002-07-31 | 2002-07-31 | |
| US60/399,395 | 2002-07-31 | ||
| PCT/CA2003/001181 WO2004011021A1 (fr) | 2002-07-31 | 2003-07-31 | Procede permettant d'accroitre et/ou d'induire une migration neuronale au moyen de l'erythropoietine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2492434A1 true CA2492434A1 (fr) | 2004-02-05 |
Family
ID=31188576
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002492434A Abandoned CA2492434A1 (fr) | 2002-07-31 | 2003-07-31 | Procede permettant d'accroitre et/ou d'induire une migration neuronale au moyen de l'erythropoietine |
Country Status (3)
| Country | Link |
|---|---|
| AU (1) | AU2003250704A1 (fr) |
| CA (1) | CA2492434A1 (fr) |
| WO (1) | WO2004011021A1 (fr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE541921T1 (de) | 2001-09-14 | 2012-02-15 | Stem Cell Therapeutics Inc | Prolaktin-induzierte zunahme an neuronalen stammzellen und dessen therapeutische anwendung |
| CA2556266A1 (fr) | 2004-02-13 | 2005-08-25 | Stem Cell Therapeutics Corp. | Utilisation de l'hormone de luteinisation (lh) et de la gonadotropine chorionique (hcg) pour la proliferation de cellules souches neuronales et la neurogenese |
| WO2007036033A1 (fr) | 2005-09-27 | 2007-04-05 | Stem Cell Therapeutics Corp. | Regulation par la prolactine de la proliferation des cellules precurseurs d'oligodendrocytes |
| WO2007106987A1 (fr) * | 2006-03-17 | 2007-09-27 | Stem Cell Therapeutics Corp. | Régimes de dosage continu pour agents de prolifération des cellules souches nerveuses et agents de différentiation desdites cellules |
| WO2008058942A2 (fr) | 2006-11-13 | 2008-05-22 | Charite - Universitätsmedezin Berlin | Procédé de culture de cellules et procédé de traitement comprenant un variant de protéines vepo |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2387748A1 (fr) * | 1999-10-20 | 2001-04-26 | Stem Cells,Inc. | Procedes d'induction de la proliferation et la migration in vivo de cellules progenitrices transplantees dans le cerveau |
-
2003
- 2003-07-31 WO PCT/CA2003/001181 patent/WO2004011021A1/fr not_active Ceased
- 2003-07-31 CA CA002492434A patent/CA2492434A1/fr not_active Abandoned
- 2003-07-31 AU AU2003250704A patent/AU2003250704A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003250704A1 (en) | 2004-02-16 |
| WO2004011021A1 (fr) | 2004-02-05 |
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| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |