CA2493673C - Method of preparing an intraocular lens for implantation - Google Patents

Method of preparing an intraocular lens for implantation Download PDF

Info

Publication number
CA2493673C
CA2493673C CA2493673A CA2493673A CA2493673C CA 2493673 C CA2493673 C CA 2493673C CA 2493673 A CA2493673 A CA 2493673A CA 2493673 A CA2493673 A CA 2493673A CA 2493673 C CA2493673 C CA 2493673C
Authority
CA
Canada
Prior art keywords
anterior
lens
lens system
posterior
optic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2493673A
Other languages
English (en)
French (fr)
Other versions
CA2493673A1 (en
Inventor
Gholam-Reza Zadno-Azizi
Albert C. Ting
Tuan Anh Nguyen
Valdemar Portney
Hai-Minh Pham
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Visiogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/207,717 external-priority patent/US20030078657A1/en
Priority claimed from US10/207,701 external-priority patent/US7198640B2/en
Priority claimed from US10/207,688 external-priority patent/US6818158B2/en
Priority claimed from US10/207,708 external-priority patent/US6884261B2/en
Priority claimed from US10/207,718 external-priority patent/US20030078658A1/en
Application filed by Visiogen Inc filed Critical Visiogen Inc
Priority to CA2767318A priority Critical patent/CA2767318C/en
Publication of CA2493673A1 publication Critical patent/CA2493673A1/en
Application granted granted Critical
Publication of CA2493673C publication Critical patent/CA2493673C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1624—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside
    • A61F2/1629—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside for changing longitudinal position, i.e. along the visual axis when implanted
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1637—Correcting aberrations caused by inhomogeneities; correcting intrinsic aberrations, e.g. of the cornea, of the surface of the natural lens, aspheric, cylindrical, toric lenses
    • A61F2/164—Aspheric lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1648—Multipart lenses
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
    • B29D11/00—Producing optical elements, e.g. lenses or prisms
    • B29D11/02—Artificial eyes from organic plastic material
    • B29D11/023—Implants for natural eyes
    • B29D11/026—Comprising more than one lens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1601—Lens body having features to facilitate aqueous fluid flow across the intraocular lens, e.g. for pressure equalization or nutrient delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1654—Diffractive lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2002/16965—Lens includes ultraviolet absorber
    • A61F2002/1699—Additional features not otherwise provided for
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2240/001—Designing or manufacturing processes
    • A61F2240/002—Designing or making customized prostheses
    • A61F2240/004—Using a positive or negative model, e.g. moulds

Landscapes

  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Transplantation (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Manufacturing & Machinery (AREA)
  • Mechanical Engineering (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
CA2493673A 2002-07-25 2003-07-24 Method of preparing an intraocular lens for implantation Expired - Fee Related CA2493673C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2767318A CA2767318C (en) 2002-07-25 2003-07-24 Accommodating intraocular lens system with separation member

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US10/207,718 2002-07-25
US10/207,717 US20030078657A1 (en) 2001-01-25 2002-07-25 Materials for use in accommodating intraocular lens system
US10/207,701 US7198640B2 (en) 2001-01-25 2002-07-25 Accommodating intraocular lens system with separation member
US10/207,688 US6818158B2 (en) 2001-01-25 2002-07-25 Accommodating intraocular lens system and method of making same
US10/207,701 2002-07-25
US10/207,708 US6884261B2 (en) 2001-01-25 2002-07-25 Method of preparing an intraocular lens for implantation
US10/207,718 US20030078658A1 (en) 2001-01-25 2002-07-25 Single-piece accomodating intraocular lens system
US10/207,688 2002-07-25
US10/207,717 2002-07-25
US10/207,708 2002-07-25
PCT/US2003/023077 WO2004010905A2 (en) 2002-07-25 2003-07-24 Intraocular lens system

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2767318A Division CA2767318C (en) 2002-07-25 2003-07-24 Accommodating intraocular lens system with separation member

Publications (2)

Publication Number Publication Date
CA2493673A1 CA2493673A1 (en) 2004-02-05
CA2493673C true CA2493673C (en) 2012-04-10

Family

ID=31192462

Family Applications (3)

Application Number Title Priority Date Filing Date
CA2493673A Expired - Fee Related CA2493673C (en) 2002-07-25 2003-07-24 Method of preparing an intraocular lens for implantation
CA2767318A Expired - Fee Related CA2767318C (en) 2002-07-25 2003-07-24 Accommodating intraocular lens system with separation member
CA2849167A Expired - Fee Related CA2849167C (en) 2002-07-25 2003-07-24 Intraocular lenses and methods of preparing or making same

Family Applications After (2)

Application Number Title Priority Date Filing Date
CA2767318A Expired - Fee Related CA2767318C (en) 2002-07-25 2003-07-24 Accommodating intraocular lens system with separation member
CA2849167A Expired - Fee Related CA2849167C (en) 2002-07-25 2003-07-24 Intraocular lenses and methods of preparing or making same

Country Status (5)

Country Link
EP (1) EP1524953A2 (de)
JP (1) JP5276762B2 (de)
AU (1) AU2003252137A1 (de)
CA (3) CA2493673C (de)
WO (1) WO2004010905A2 (de)

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US8556967B2 (en) 1999-04-09 2013-10-15 Faezeh Mona Sarfarazi Interior bag for a capsular bag and injector
US7780729B2 (en) 2004-04-16 2010-08-24 Visiogen, Inc. Intraocular lens
US7217112B2 (en) 2003-05-27 2007-05-15 Faezeh Mona Sarfarazi Mold for intraocular lens
IL161706A0 (en) 2004-04-29 2004-09-27 Nulens Ltd Intraocular lens fixation device
US8057217B2 (en) * 2004-09-30 2011-11-15 Bausch + Lomb Incorporated Apparatus and method for injection molding an intraocular lens device
EP1890650A2 (de) 2005-03-30 2008-02-27 Nulens Ltd Akkommodierende intraokularlinsen- (aiol) anordungen und diskrete komponenten dafür
US20070260309A1 (en) * 2006-05-08 2007-11-08 Richardson Gary A Accommodating intraocular lens having a recessed anterior optic
US7998198B2 (en) * 2008-02-07 2011-08-16 Novartis Ag Accommodative IOL with dynamic spherical aberration
TWI507183B (zh) * 2009-09-04 2015-11-11 Alcon Inc 具晶體間混濁化抗性之眼內晶體
US9114005B2 (en) * 2009-11-17 2015-08-25 Akkolens International B.V. Accommodative intraocular lens driven by ciliary mass
WO2011137191A1 (en) * 2010-04-27 2011-11-03 Ramgopal Rao Accommodating intraocular lens device
WO2012045183A1 (en) * 2010-10-06 2012-04-12 Eduard Anton Haefliger Intraocular lens implant
CA2824656A1 (en) * 2010-12-29 2012-07-05 Elenza, Inc. Devices and methods for dynamic focusing movement
US20120253459A1 (en) 2011-02-04 2012-10-04 Cary Reich Intraocular accommodating lens and methods of use
US9372282B1 (en) 2011-08-31 2016-06-21 Novartis Ag Styrenic ophthalmic and otorhinolaryngological materials and devices formed therewith
DE102012016893A1 (de) * 2012-08-24 2014-05-15 Be Innovative Gmbh Intraokularlinse, insbesondere Kapselsackintraokularlinse
US9486311B2 (en) 2013-02-14 2016-11-08 Shifamed Holdings, Llc Hydrophilic AIOL with bonding
US10195018B2 (en) 2013-03-21 2019-02-05 Shifamed Holdings, Llc Accommodating intraocular lens
CA3193600A1 (en) 2013-03-21 2014-09-25 Shifamed Holdings, Llc Accommodating intraocular lens
JP5481588B1 (ja) 2013-05-13 2014-04-23 株式会社Ｆｒｏｎｔｉｅｒ Ｖｉｓｉｏｎ 調節眼内レンズ
JP6591525B2 (ja) 2014-03-28 2019-10-16 フォーサイト・ラブス・リミテッド・ライアビリティ・カンパニーＦｏｒＳｉｇｈｔ Ｌａｂｓ， ＬＬＣ 遠近調節型の眼内レンズ
EP4574093A3 (de) 2014-08-26 2025-09-17 Shifamed Holdings, LLC Akkommodierende intraokularlinse
JP6708653B2 (ja) * 2015-03-11 2020-06-10 アルコン インコーポレイティド 眼内レンズを製造する装置および方法
CA3005338A1 (en) 2015-11-18 2017-05-26 Shifamed Holdings, Llc Multi-piece accommodating intraocular lens
US11141263B2 (en) 2015-11-18 2021-10-12 Shifamed Holdings, Llc Multi-piece accommodating intraocular lens
WO2018081595A1 (en) 2016-10-28 2018-05-03 Forsight Vision6, Inc. Accommodating intraocular lens and methods of implantation
CN120000379A (zh) 2016-12-23 2025-05-16 施菲姆德控股有限责任公司 多片式调节性人工晶状体及其制造和使用方法
US10350056B2 (en) 2016-12-23 2019-07-16 Shifamed Holdings, Llc Multi-piece accommodating intraocular lenses and methods for making and using same
EP3634308A4 (de) 2017-05-30 2021-02-24 Shifamed Holdings, LLC Oberflächenbehandlungen zur aufnahme von intraokularlinsen und zugehörige verfahren und vorrichtungen
EP3634309B1 (de) 2017-06-07 2023-05-24 Shifamed Holdings, LLC Intraokularlinsen mit einstellbarer optischer stärke
GB2565152B (en) * 2017-08-04 2020-06-03 Rayner Intraocular Lenses Ltd Intraocular lens
WO2020197386A1 (en) 2019-03-25 2020-10-01 Akkolens International B.V. Intraocular lens combination for restoration of refraction and accommodation
WO2020231260A1 (en) 2019-05-15 2020-11-19 Akkolens International B.V. Accommodating intraocular lenses with combination of mechanical driving components
US12521232B2 (en) 2019-07-11 2026-01-13 Shifamed Holdings, Llc Accommodating intraocular lenses and associated methods
CN114375185A (zh) 2019-08-19 2022-04-19 爱克透镜国际公司 具有独立固定和可变焦度晶状体部分的可调节人工晶状体组合
NL2027301B1 (en) 2020-01-13 2021-10-26 Akkolens Int B V Mechanical means for accommodative intraocular lens
KR102482346B1 (ko) * 2020-01-22 2022-12-29 주식회사 오토스윙 용접 정보 제공 장치
NL2028038B1 (en) 2020-05-11 2022-07-04 Akkolens Int B V Method to connect and distance hydrophilic intraocular lens elements
US12336903B2 (en) 2021-01-13 2025-06-24 Forsight Vision6, Inc. Variable thickness dynamic membrane for accommodating intraocular lenses

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US5275623A (en) * 1991-11-18 1994-01-04 Faezeh Sarfarazi Elliptical accommodative intraocular lens for small incision surgery
FR2747564B1 (fr) * 1996-04-22 1999-01-29 W K Et Associes Emballage pour le pliage des implants intraoculaires
US5876406A (en) * 1996-08-02 1999-03-02 Staar Surgical Company, Inc. Deformable intraocular lens injecting apparatus with transverse hinged lens cartridge
US6488708B2 (en) * 1999-04-09 2002-12-03 Faezeh Sarfarazi Open chamber, elliptical, accommodative intraocular lens system
US6616692B1 (en) * 1999-04-30 2003-09-09 Advanced Medical Optics, Inc. Intraocular lens combinations
US6599317B1 (en) * 1999-09-17 2003-07-29 Advanced Medical Optics, Inc. Intraocular lens with a translational zone
JP3728155B2 (ja) * 1999-10-05 2005-12-21 キヤノンスター株式会社 眼内挿入用レンズの挿入システム
US6797004B1 (en) * 2000-03-02 2004-09-28 Advanced Medical Optics, Inc. Holders for intraocular lenses
JP4184800B2 (ja) * 2001-01-25 2008-11-19 ゴラン−レザ・ザドノ−アズィズィ 遠近調節可能な眼内レンズシステム
US6884263B2 (en) * 2001-07-17 2005-04-26 Medennium, Inc. Accommodative intraocular lens

Also Published As

Publication number Publication date
WO2004010905A2 (en) 2004-02-05
CA2849167C (en) 2016-06-28
EP1524953A2 (de) 2005-04-27
JP5276762B2 (ja) 2013-08-28
CA2849167A1 (en) 2004-02-05
CA2493673A1 (en) 2004-02-05
WO2004010905A3 (en) 2004-05-13
AU2003252137A1 (en) 2004-02-16
CA2767318A1 (en) 2004-02-05
JP2005533611A (ja) 2005-11-10
CA2767318C (en) 2014-07-22

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