CA2495480A1 - Hybride d'interferon et de fragment fc d'immunoglobuline - Google Patents

Hybride d'interferon et de fragment fc d'immunoglobuline Download PDF

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Publication number
CA2495480A1
CA2495480A1 CA002495480A CA2495480A CA2495480A1 CA 2495480 A1 CA2495480 A1 CA 2495480A1 CA 002495480 A CA002495480 A CA 002495480A CA 2495480 A CA2495480 A CA 2495480A CA 2495480 A1 CA2495480 A1 CA 2495480A1
Authority
CA
Canada
Prior art keywords
interferon
protein
fragment
ifn
hybrid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002495480A
Other languages
English (en)
Inventor
Tse Wen Chang
Liming Yu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority claimed from PCT/US2002/025154 external-priority patent/WO2004022088A1/fr
Publication of CA2495480A1 publication Critical patent/CA2495480A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne des protéines de fusion interféron-immunoglobuline Fc (<= hybrides IFN-Fc >=) qui sont utiles pour enlever ou faire régresser des tumeurs ou pour retarder leur évolution. Ces hybrides comprennent de préférence des peptides de liaison entre l'IFN et le fragment Fc. Ces lieurs sont des séquences inertes de lymphocytes T ou une séquence non-immunogène quelconque, de préférence des unités de répétition Gly-Ser. Le fragment Fc préféré est un fragment Fc d'immunoglobuline humain, de préférence la chaîne .gamma.4.
CA002495480A 2002-08-07 2002-08-07 Hybride d'interferon et de fragment fc d'immunoglobuline Abandoned CA2495480A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2002/025154 WO2004022088A1 (fr) 1999-10-15 2002-08-07 Hybride d'interféron et de fragment fc d'immunoglobuline

Publications (1)

Publication Number Publication Date
CA2495480A1 true CA2495480A1 (fr) 2004-03-18

Family

ID=34271615

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002495480A Abandoned CA2495480A1 (fr) 2002-08-07 2002-08-07 Hybride d'interferon et de fragment fc d'immunoglobuline

Country Status (3)

Country Link
EP (1) EP1536825A4 (fr)
AU (1) AU2002313730A1 (fr)
CA (1) CA2495480A1 (fr)

Also Published As

Publication number Publication date
EP1536825A4 (fr) 2007-09-12
AU2002313730A1 (en) 2004-03-29
EP1536825A1 (fr) 2005-06-08

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead