CA2499273C - Compositions a inhaler - Google Patents

Compositions a inhaler Download PDF

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Publication number
CA2499273C
CA2499273C CA2499273A CA2499273A CA2499273C CA 2499273 C CA2499273 C CA 2499273C CA 2499273 A CA2499273 A CA 2499273A CA 2499273 A CA2499273 A CA 2499273A CA 2499273 C CA2499273 C CA 2499273C
Authority
CA
Canada
Prior art keywords
dry powder
microns
diameter
particles
lactose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2499273A
Other languages
English (en)
Other versions
CA2499273A1 (fr
Inventor
Xian-Ming Zeng
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Norton Healthcare Ltd
Original Assignee
Norton Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9942746&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2499273(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Norton Healthcare Ltd filed Critical Norton Healthcare Ltd
Publication of CA2499273A1 publication Critical patent/CA2499273A1/fr
Application granted granted Critical
Publication of CA2499273C publication Critical patent/CA2499273C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Otolaryngology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention porte sur une composition à inhaler de poudre sèche contenant des particules de médicament et un mélange de particules de lactose avec diamètre volumétrique moyen compris entre environ 70 et 120 microns et un diamètre inférieur à 250 microns. Le mélange se caractérise par le fait que jusqu'à 96 % en poids des particules de lactose possèdent un diamètre inférieur à 150 microns, 25 % en poids des particules de lactose ont un diamètre inférieur à 5 microns. Ces compositions fournissent une dispersion plus précise, uniforme et régulière lorsqu'elles sont utilisées par exemple avec un inhalateur de poudre sèche. L'invention concerne aussi des procédés d'utilisation des compositions susmentionnées.
CA2499273A 2002-08-21 2003-08-21 Compositions a inhaler Expired - Fee Related CA2499273C (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0219513A GB0219513D0 (en) 2002-08-21 2002-08-21 Inhalation compositions including coarse carrier
GB02119513.7 2002-08-21
GB02119513.9 2002-08-21
PCT/US2003/026385 WO2004017914A2 (fr) 2002-08-21 2003-08-21 Compositions a inhaler

Publications (2)

Publication Number Publication Date
CA2499273A1 CA2499273A1 (fr) 2004-03-04
CA2499273C true CA2499273C (fr) 2011-06-21

Family

ID=9942746

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2499273A Expired - Fee Related CA2499273C (fr) 2002-08-21 2003-08-21 Compositions a inhaler

Country Status (8)

Country Link
BR (1) BRPI0313647A2 (fr)
CA (1) CA2499273C (fr)
ES (1) ES2371601T3 (fr)
GB (1) GB0219513D0 (fr)
NO (1) NO20051461L (fr)
TN (1) TNSN05047A1 (fr)
WO (1) WO2004017914A2 (fr)
ZA (1) ZA200502177B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005102429A1 (fr) 2004-04-21 2005-11-03 Innovata Biomed Limited Inhalateur
CN101098678A (zh) 2004-04-23 2008-01-02 锡德克斯公司 含有磺基烷基醚环糊精的dpi制剂
GB0409197D0 (en) 2004-04-24 2004-05-26 Innovata Biomed Ltd Device
MX2007009656A (es) 2005-02-10 2007-11-07 Glaxo Group Ltd Proceso para elaborar lactosa utilizando tecnicas de clasificacion previa y formulaciones farmaceuticas formadas de la misma.
US7629331B2 (en) 2005-10-26 2009-12-08 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof
GB0605723D0 (en) 2006-03-23 2006-05-03 3M Innovative Properties Co Powder filling processes
WO2008134817A1 (fr) * 2007-05-03 2008-11-13 The University Of Sydney Vecteurs composites pour thérapie par inhalation de poudre sèche
TR201205852A2 (tr) * 2011-06-02 2012-12-21 Bi̇lgi̇ç Mahmut Geliştirilmiş yeni kuru toz formülasyonu.
TR201105367A2 (tr) * 2011-06-02 2012-12-21 Bi̇lgi̇ç Mahmut Akış özellikleri geliştirilmiş bir kuru toz formülasyonu.
UA115989C2 (uk) 2012-07-05 2018-01-25 Арвен Айлак Санайі Ве Тіджарет А.С. Фармацевтична композиція для інгалятора сухого порошку, що містить антагоністи мускаринових рецепторів тривалої дії
EP2874928B1 (fr) 2012-07-19 2016-06-15 Adamis Pharmaceuticals Corporation Appareil d'acheminement de poudre
JP6251667B2 (ja) 2014-06-03 2017-12-20 アサヒカルピスウェルネス株式会社 錠剤型即放性製剤及びその製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL200941B1 (pl) * 1998-11-13 2009-02-27 Jagotec Ag Suchy proszkowy preparat inhalacyjny
AU1786199A (en) * 1998-12-11 2000-07-03 Pharmachemie B.V. Pharmaceutical preparation for inhalation of an opioid
TR200402367T4 (tr) 2000-10-12 2004-12-21 Boehringer Ingelheim Pharma Gmbh& Co.Kg Yeni tiotropyum içeren inhalasyon tozları
UA75375C2 (en) 2000-10-12 2006-04-17 Boehringer Ingelheim Pharma Method for producing powdery preparations for inhaling

Also Published As

Publication number Publication date
TNSN05047A1 (en) 2007-05-14
CA2499273A1 (fr) 2004-03-04
BRPI0313647A2 (pt) 2019-02-19
GB0219513D0 (en) 2002-10-02
WO2004017914A8 (fr) 2005-07-07
WO2004017914A2 (fr) 2004-03-04
NO20051461L (no) 2005-05-20
ES2371601T3 (es) 2012-01-05
WO2004017914A3 (fr) 2004-04-29
ZA200502177B (en) 2006-05-31

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20180821