CA2522329A1 - Inhibiteurs de coronavirus - Google Patents

Inhibiteurs de coronavirus Download PDF

Info

Publication number
CA2522329A1
CA2522329A1 CA002522329A CA2522329A CA2522329A1 CA 2522329 A1 CA2522329 A1 CA 2522329A1 CA 002522329 A CA002522329 A CA 002522329A CA 2522329 A CA2522329 A CA 2522329A CA 2522329 A1 CA2522329 A1 CA 2522329A1
Authority
CA
Canada
Prior art keywords
peptide
seq
ile
leu
lys
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002522329A
Other languages
English (en)
Inventor
Peter S. Kim
Debra Eckert
Victor M. Garsky
Roger M. Freidinger
Romas Geleziunas
Antonello Pessi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Istituto di Ricerche di Biologia Molecolare P Angeletti SpA
Merck and Co Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2522329A1 publication Critical patent/CA2522329A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2810/00—Vectors comprising a targeting moiety
    • C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
    • C12N2810/60—Vectors comprising as targeting moiety peptide derived from defined protein from viruses
    • C12N2810/609—Vectors comprising as targeting moiety peptide derived from defined protein from viruses positive strand RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CA002522329A 2003-04-14 2004-04-12 Inhibiteurs de coronavirus Abandoned CA2522329A1 (fr)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US46310003P 2003-04-14 2003-04-14
US60/463,100 2003-04-14
US46719003P 2003-04-30 2003-04-30
US60/467,190 2003-04-30
US47886003P 2003-06-16 2003-06-16
US60/478,860 2003-06-16
US47943003P 2003-06-18 2003-06-18
US47942903P 2003-06-18 2003-06-18
US60/479,429 2003-06-18
US60/479,430 2003-06-18
PCT/US2004/011210 WO2005002500A2 (fr) 2003-04-14 2004-04-12 Inhibiteurs de coronavirus

Publications (1)

Publication Number Publication Date
CA2522329A1 true CA2522329A1 (fr) 2005-01-13

Family

ID=33568933

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002522329A Abandoned CA2522329A1 (fr) 2003-04-14 2004-04-12 Inhibiteurs de coronavirus

Country Status (3)

Country Link
EP (1) EP1615610A2 (fr)
CA (1) CA2522329A1 (fr)
WO (1) WO2005002500A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111349150A (zh) * 2020-03-24 2020-06-30 北京中科微盾生物科技有限责任公司 一种抑制新型冠状病毒的多肽及其用途

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050186575A1 (en) * 2001-05-17 2005-08-25 Rottier Petrus J.M. Corona-virus-like particles comprising functionally deleted genomes
WO2015143335A1 (fr) * 2014-03-20 2015-09-24 The University Of North Carolina At Chapel Hill Méthodes et compositions pour protéines spike de coronavirus chimère
CN107022008B (zh) * 2016-01-30 2021-04-23 山西锦波生物医药股份有限公司 广谱地抑制人类冠状病毒感染的多肽及其应用
WO2021183463A1 (fr) * 2020-03-09 2021-09-16 President And Fellows Of Harvard College Compositions et méthodes pour traiter du coronavirus
CN111471088B (zh) * 2020-04-21 2021-02-09 北京中科微盾生物科技有限责任公司 一种抑制sars-cov-2感染的多肽、组合物及其用途
US11767353B2 (en) * 2020-06-05 2023-09-26 Theraly Fibrosis, Inc. Trail compositions with reduced immunogenicity
US10906944B2 (en) * 2020-06-29 2021-02-02 The Scripps Research Institute Stabilized coronavirus spike (S) protein immunogens and related vaccines
US11479582B2 (en) 2020-10-16 2022-10-25 King Faisal University Anti-SARS-CoV-2 fusion peptides
WO2022159372A1 (fr) * 2021-01-22 2022-07-28 Decoy Therapeutics, Inc. Procédés et compositions pour traiter des infections
CN117396492A (zh) * 2021-03-30 2024-01-12 贝勒医学院 用于基于多肽的高效蛋白抑制的方法和组合物
CN113072623B (zh) * 2021-04-28 2022-10-14 苏州大学 一种靶向SARS-CoV-2 N蛋白的干扰肽的制备方法及应用
CN115925825B (zh) * 2021-08-16 2023-07-04 中国科学院微生物研究所 一种抗新型冠状病毒的多肽及其应用

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111349150A (zh) * 2020-03-24 2020-06-30 北京中科微盾生物科技有限责任公司 一种抑制新型冠状病毒的多肽及其用途
CN111349150B (zh) * 2020-03-24 2021-02-09 北京中科微盾生物科技有限责任公司 一种抑制新型冠状病毒的多肽及其用途

Also Published As

Publication number Publication date
EP1615610A2 (fr) 2006-01-18
WO2005002500A3 (fr) 2006-10-05
WO2005002500A2 (fr) 2005-01-13

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Legal Events

Date Code Title Description
FZDE Discontinued