CA2528095C - Compositions pour l'inactivation de micro-organismes pathogenes, procedes de fabrication de compositions, et leurs procedes d'utilisation - Google Patents
Compositions pour l'inactivation de micro-organismes pathogenes, procedes de fabrication de compositions, et leurs procedes d'utilisation Download PDFInfo
- Publication number
- CA2528095C CA2528095C CA2528095A CA2528095A CA2528095C CA 2528095 C CA2528095 C CA 2528095C CA 2528095 A CA2528095 A CA 2528095A CA 2528095 A CA2528095 A CA 2528095A CA 2528095 C CA2528095 C CA 2528095C
- Authority
- CA
- Canada
- Prior art keywords
- methods
- compositions
- making
- pathogenic microorganisms
- inactivating pathogenic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 230000000415 inactivating effect Effects 0.000 title abstract 2
- 244000000010 microbial pathogen Species 0.000 title abstract 2
- 239000007908 nanoemulsion Substances 0.000 abstract 3
- 239000008346 aqueous phase Substances 0.000 abstract 1
- 230000006806 disease prevention Effects 0.000 abstract 1
- 230000002779 inactivation Effects 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000012071 phase Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La présente invention a trait à des compositions de nanoémulsions à faible toxicité présentant une inactivation d'une grande variété de micro-organismes ou de prévention de maladies. Les nanoémulsions contiennent une phase aqueuse, une phase huileuse, comprenant une huile et un solvant organique, et un ou des tensioactifs. L'invention a également trait à des procédés de fabrication de nanoémulsions et d'inactivation de micro-organismes pathogènes.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45763303P | 2003-06-04 | 2003-06-04 | |
| US60/475,633 | 2003-06-04 | ||
| PCT/US2004/017417 WO2005027872A2 (fr) | 2003-06-04 | 2004-06-03 | Compositions pour l'inactivation de micro-organismes pathogenes, procedes de fabrication de compositions, et leurs procedes d'utilisation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2528095A1 CA2528095A1 (fr) | 2005-03-31 |
| CA2528095C true CA2528095C (fr) | 2014-10-14 |
Family
ID=34375188
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2528095A Expired - Lifetime CA2528095C (fr) | 2003-06-04 | 2004-06-03 | Compositions pour l'inactivation de micro-organismes pathogenes, procedes de fabrication de compositions, et leurs procedes d'utilisation |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1633322A2 (fr) |
| AU (1) | AU2004273779B2 (fr) |
| CA (1) | CA2528095C (fr) |
| WO (1) | WO2005027872A2 (fr) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7763663B2 (en) | 2001-12-19 | 2010-07-27 | University Of Massachusetts | Polysaccharide-containing block copolymer particles and uses thereof |
| WO2004100890A2 (fr) | 2003-05-09 | 2004-11-25 | The Trustees Of Columbia University In The City Of New York | Procedes lies a la fonction rage g82s et compositions destinees au traitement de troubles inflammatoires |
| AU2016244292A1 (en) * | 2005-07-18 | 2016-11-03 | University Of Massachusetts Lowell | Compositions and methods for making and using nanoemulsions |
| KR20130079645A (ko) | 2005-07-18 | 2013-07-10 | 유니버시티 오브 메사츄세츠 로웰 | 나노에멀젼 조성물 및 이의 제조 및 사용 방법 |
| CA2618974C (fr) | 2005-08-09 | 2014-01-28 | Nanobio Corporation | Compositions de nanoemulsions possedant une activite anti-inflammatoire |
| CN101374498A (zh) | 2005-12-01 | 2009-02-25 | 麻萨诸塞州洛厄尔大学 | 肉毒杆菌纳米乳液 |
| US9486408B2 (en) | 2005-12-01 | 2016-11-08 | University Of Massachusetts Lowell | Botulinum nanoemulsions |
| AU2007240983A1 (en) * | 2006-04-07 | 2007-11-01 | Novavax, Inc. | Nanostructured compositions having antibacterial, anti-fungal, anti-yeast, and/or anti-viral properties |
| WO2007120860A2 (fr) * | 2006-04-13 | 2007-10-25 | The Regents Of The University Of Michigan | Vaccins à base d'une nanoémulsion |
| US10138279B2 (en) | 2006-04-13 | 2018-11-27 | Regents Of The University Of Michigan | Compositions and methods for Bacillus anthracis vaccination |
| US9839685B2 (en) | 2006-04-13 | 2017-12-12 | The Regents Of The University Of Michigan | Methods of inducing human immunodeficiency virus-specific immune responses in a host comprising nasally administering compositions comprising a naonemulsion and recombinant GP120 immunogen |
| FR2907012B1 (fr) * | 2006-10-12 | 2012-09-21 | Galderma Sa | Composition dermatologique comprenant des nanocapsules d'avermectine, son procede de preparation et son utilisation |
| WO2008070538A2 (fr) | 2006-12-01 | 2008-06-12 | Anterios, Inc. | Nanoparticules à entités amphiphiles |
| SG10201607909WA (en) | 2006-12-01 | 2016-11-29 | Anterios Inc | Peptide nanoparticles and uses therefor |
| EP1938801A1 (fr) | 2006-12-22 | 2008-07-02 | Biofrontera Bioscience GmbH | Nanoémulsion |
| DE102007007698A1 (de) * | 2007-02-09 | 2008-08-21 | Exner, Heinrich, Dr. | Verwendung einer hochemulgierten Silikonöl-Emulsion (HSE)zur Herstellung eines Medikamentes |
| CN101765423B (zh) | 2007-05-31 | 2014-08-06 | 安特里奥公司 | 核酸纳米粒子和其用途 |
| BRPI0705564B8 (pt) * | 2007-10-10 | 2021-05-25 | Embrapa Pesquisa Agropecuaria | sistema do tipo cristal líquido contínuo contendo co-solvente portador de substâncias fracamente solúveis em água, seu processo de obtenção e seus usos |
| US9144606B2 (en) | 2008-04-21 | 2015-09-29 | Nanobio Corporation | Nanoemulsion influenza vaccine |
| WO2009132342A1 (fr) * | 2008-04-25 | 2009-10-29 | Nanobio Corporation | Nanoemulsions destinées à traiter des infections fongiques, et des infections provoquées par de la levure et de la moisissure |
| US20090269394A1 (en) * | 2008-04-25 | 2009-10-29 | Nanobio Corporation | Methods and compositions for treating onchomycosis |
| WO2009143524A2 (fr) | 2008-05-23 | 2009-11-26 | The Regents Of The University Of Michigan | Vaccins à nanoémulsion |
| KR102080429B1 (ko) * | 2008-06-26 | 2020-02-21 | 안테리오스, 인코퍼레이티드 | 경피 운반 |
| EP2349209A2 (fr) | 2008-09-26 | 2011-08-03 | Nanobio Corporation | Compositions thérapeutiques de nanoémulsion et procédés d'utilisation de celles-ci |
| EP2370057A1 (fr) * | 2008-12-31 | 2011-10-05 | Sunev Pharma Solution Limited Corporate | Nouvelles formules phytosanitaires topiques pour le traitement de l'acné et des troubles cutanés |
| AU2010255336A1 (en) * | 2009-06-05 | 2012-01-12 | Sunev Pharma Solution Limited | Topical micro-emulsions for the treatment of rheumatic disorders |
| DE102009056883B4 (de) | 2009-12-03 | 2012-08-16 | Novartis Ag | Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben |
| DK2343052T3 (da) | 2009-12-03 | 2013-09-02 | Novartis Ag | Hydrofil filtrering under fremstilling af vaccineadjuvanter |
| EP2506834B1 (fr) | 2009-12-03 | 2016-03-02 | Novartis AG | Circulation de constituants lors de l'homogénéisation et de la microfluidisation d'émulsions |
| DE102009056871A1 (de) | 2009-12-03 | 2011-06-22 | Novartis AG, 4056 | Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben |
| AU2013213678B2 (en) * | 2009-12-03 | 2016-06-23 | Seqirus UK Limited | Arranging interaction and back pressure chambers for microfluidization |
| CL2012001399A1 (es) | 2009-12-03 | 2013-03-08 | Novartis Ag | Metodo para fabricar adyuvante para vacuna (emulsion aceite/agua con escualeno, polisorbato 80 y trioleato de sorbitan), que comprende (i) formar primera emulsion en homogenizador desde un contendor a otro para formar segunda emulsion, (ii) y microfluidizar primera emulsion para formar segunda emulsion. |
| DE102009056884B4 (de) | 2009-12-03 | 2021-03-18 | Novartis Ag | Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben |
| PL2380558T5 (pl) † | 2009-12-03 | 2020-10-05 | Novartis Ag | Wytwarzanie emulsji w układzie komory oddziaływań i komory przeciwciśnieniowej do mikrofluidyzacji |
| DE202010004750U1 (de) * | 2010-04-09 | 2011-10-11 | Biofrontera Bioscience Gmbh | Pharmazeutische oder/und kosmetische Zusammensetzung zur Behandlung der Haut |
| WO2013163176A1 (fr) | 2012-04-23 | 2013-10-31 | Allertein Therapeutics, Llc | Nanoparticules pour le traitement d'allergies |
| WO2014206857A1 (fr) * | 2013-06-28 | 2014-12-31 | Universitat Autonoma De Barcelona | Formulations huile-dans-l'eau de mycobacterium et utilisations associées |
| CN106535632A (zh) * | 2014-03-21 | 2017-03-22 | 弗罗里达大学研究基金会有限公司 | 用纳米颗粒和/或纳米乳液配制的醛在增强植物对黄龙病菌的疾病抗性中的用途 |
| CN104274405A (zh) * | 2014-10-21 | 2015-01-14 | 河南牧翔动物药业有限公司 | 一种水包油型复方头孢噻呋纳米乳抗菌药物 |
| EP3253372B8 (fr) * | 2015-02-06 | 2022-06-22 | Woodstock Sterile Solutions, Inc. | Préparation d'une émulsion huile dans l'eau pour formulations pharmaceutiques stabilisées par un polymère |
| EP3510161A4 (fr) | 2016-08-23 | 2020-04-22 | Akouos, Inc. | Compositions et méthodes pour traiter une déficience auditive non associée à l'âge chez un sujet humain |
| EP3541358A1 (fr) | 2016-11-21 | 2019-09-25 | Eirion Therapeutics, Inc. | Administration transdermique de grands agents |
| CN106924730B (zh) * | 2017-02-14 | 2019-11-08 | 商丘美兰生物工程有限公司 | 猪伪狂犬病毒芦荟胶纳米乳佐剂灭活苗及其制备方法 |
| JP7432506B2 (ja) | 2017-10-30 | 2024-02-16 | 武田薬品工業株式会社 | 脂質エンベロープウイルスを不活化するための環境適合性の界面活性剤 |
| US11344484B2 (en) * | 2018-01-23 | 2022-05-31 | Conopco, Inc. | Process for making transparent nanoemulsions comprising lauric oil |
| BR112020011757B1 (pt) * | 2018-01-23 | 2022-03-29 | Unilever Ip Holdings B.V. | Nanoemulsão óleo em água |
| CN116096905A (zh) | 2020-02-21 | 2023-05-09 | 阿库斯股份有限公司 | 用于治疗人受试者的非年龄相关性听力损伤的组合物和方法 |
| CN113662006B (zh) * | 2021-06-30 | 2022-05-20 | 南京凯创协同纳米技术有限公司 | 一种可杀灭细菌灭活病毒的微纳锌的制备方法 |
| KR102891033B1 (ko) * | 2022-06-30 | 2025-12-01 | 씨제이제일제당(주) | 의료용 조성물 |
| JP2025525354A (ja) * | 2022-06-30 | 2025-08-05 | シージェイ チェイルジェダン コーポレーション | 医療用組成物 |
| WO2024208433A1 (fr) | 2023-04-06 | 2024-10-10 | Biofrontera Bioscience Gmbh | Nanoémulsion sans propylène glycol |
| WO2024208434A1 (fr) | 2023-04-06 | 2024-10-10 | Biofrontera Bioscience Gmbh | Nanoémulsion sous pression |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2912426B2 (ja) * | 1990-06-15 | 1999-06-28 | 鐘紡株式会社 | 微細化エマルション組成物 |
| US6506803B1 (en) * | 1999-04-28 | 2003-01-14 | Regents Of The University Of Michigan | Methods of preventing and treating microbial infections |
| JP4072057B2 (ja) * | 2000-12-27 | 2008-04-02 | アレス トレーディング ソシエテ アノニム | ペプチド及び/またはタンパク質取り込み用の両親媒性脂質ナノ粒子 |
| AU2002367976B2 (en) * | 2001-06-05 | 2007-06-21 | The Regents Of The University Of Michigan | Nanoemulsion vaccines |
-
2004
- 2004-06-03 CA CA2528095A patent/CA2528095C/fr not_active Expired - Lifetime
- 2004-06-03 WO PCT/US2004/017417 patent/WO2005027872A2/fr not_active Ceased
- 2004-06-03 AU AU2004273779A patent/AU2004273779B2/en not_active Expired
- 2004-06-03 EP EP04809431A patent/EP1633322A2/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005027872A2 (fr) | 2005-03-31 |
| WO2005027872A3 (fr) | 2006-03-09 |
| CA2528095A1 (fr) | 2005-03-31 |
| AU2004273779A2 (en) | 2005-03-31 |
| EP1633322A2 (fr) | 2006-03-15 |
| AU2004273779A1 (en) | 2005-03-31 |
| AU2004273779B2 (en) | 2009-10-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |