CA2546391A1 - Procedes de modelisation de toxicologie moleculaire - Google Patents

Procedes de modelisation de toxicologie moleculaire Download PDF

Info

Publication number
CA2546391A1
CA2546391A1 CA002546391A CA2546391A CA2546391A1 CA 2546391 A1 CA2546391 A1 CA 2546391A1 CA 002546391 A CA002546391 A CA 002546391A CA 2546391 A CA2546391 A CA 2546391A CA 2546391 A1 CA2546391 A1 CA 2546391A1
Authority
CA
Canada
Prior art keywords
gene
score
toxicity
data
model
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002546391A
Other languages
English (en)
Inventor
James C. Diggans
Michael Elashoff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ocimum Biosolutions Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2003/037556 external-priority patent/WO2004048598A2/fr
Application filed by Individual filed Critical Individual
Publication of CA2546391A1 publication Critical patent/CA2546391A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Theoretical Computer Science (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biotechnology (AREA)
  • Evolutionary Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA002546391A 2003-11-24 2004-11-24 Procedes de modelisation de toxicologie moleculaire Abandoned CA2546391A1 (fr)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
USPCT/US2003/037556 2003-11-24
PCT/US2003/037556 WO2004048598A2 (fr) 2002-11-22 2003-11-24 Modelage nephrotoxicologique moleculaire
US55498104P 2004-03-22 2004-03-22
US60/554,981 2004-03-22
US61383104P 2004-09-29 2004-09-29
US60/613,831 2004-09-29
PCT/US2004/039593 WO2005052181A2 (fr) 2003-11-24 2004-11-24 Procedes de modelisation de toxicologie moleculaire

Publications (1)

Publication Number Publication Date
CA2546391A1 true CA2546391A1 (fr) 2005-06-09

Family

ID=34637018

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002546391A Abandoned CA2546391A1 (fr) 2003-11-24 2004-11-24 Procedes de modelisation de toxicologie moleculaire

Country Status (4)

Country Link
EP (1) EP1697873A4 (fr)
JP (1) JP2007535305A (fr)
CA (1) CA2546391A1 (fr)
WO (1) WO2005052181A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111989574A (zh) * 2018-04-06 2020-11-24 勃林格殷格翰维特梅迪卡有限公司 用于确定分析物的方法和分析系统

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2891278B1 (fr) * 2005-09-23 2008-07-04 Vigilent Technologies Sarl Procede pour determiner l'etat d'un ensemble de cellules et systeme pour la mise en oeuvre dudit procede
WO2009083030A1 (fr) * 2007-12-27 2009-07-09 Vereniging Voor Christelijk Hoger Onderwijs Méthode de prédiction de l'effet toxique d'un composé
EP2754075A2 (fr) * 2011-09-09 2014-07-16 Philip Morris Products S.a.s. Systèmes et procédés d'évaluation d'activités biologiques basée sur un réseau
JP6313757B2 (ja) 2012-06-21 2018-04-18 フィリップ モリス プロダクツ エス アー 統合デュアルアンサンブルおよび一般化シミュレーテッドアニーリング技法を用いてバイオマーカシグネチャを生成するためのシステムおよび方法
CA2877429C (fr) 2012-06-21 2020-11-03 Philip Morris Products S.A. Systemes et procedes pour generer des signatures de biomarqueurs avec correction de biais et prediction de classe integrees
CN113496072B (zh) * 2020-03-22 2024-07-02 杭州环特生物科技股份有限公司 用于安全性评价的斑马鱼转换人用剂量的换算方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6132969A (en) * 1998-06-19 2000-10-17 Rosetta Inpharmatics, Inc. Methods for testing biological network models
KR100865664B1 (ko) * 2000-06-14 2008-10-29 비스타겐 인코포레이티드 간 줄기 세포를 사용하는 독성 타이핑
CA2414421A1 (fr) * 2000-07-31 2002-02-07 Gene Logic, Inc. Modelisation en toxicologie moleculaire
US20030154032A1 (en) * 2000-12-15 2003-08-14 Pittman Debra D. Methods and compositions for diagnosing and treating rheumatoid arthritis
US7993907B2 (en) * 2001-05-08 2011-08-09 Mowycal Lending, Llc Biochips and method of screening using drug induced gene and protein expression profiling
CA2446853A1 (fr) * 2001-05-15 2002-11-21 Psychogenics Inc. Systemes et procedes de controle informatique du comportement
CA2478640A1 (fr) * 2002-03-13 2003-09-18 F. Hoffmann-La Roche Ag Procede pour selectionner des facteurs determinant la sensibilite a des medicaments et procede pour predire la sensibilite a des medicaments a partir des facteurs ainsi selectionnes

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111989574A (zh) * 2018-04-06 2020-11-24 勃林格殷格翰维特梅迪卡有限公司 用于确定分析物的方法和分析系统

Also Published As

Publication number Publication date
JP2007535305A (ja) 2007-12-06
EP1697873A2 (fr) 2006-09-06
WO2005052181A3 (fr) 2006-04-27
EP1697873A4 (fr) 2008-01-23
WO2005052181A2 (fr) 2005-06-09

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Legal Events

Date Code Title Description
FZDE Discontinued