CA2587429C - 5-aminopyrazole derivatives as pesticidal compounds - Google Patents

5-aminopyrazole derivatives as pesticidal compounds Download PDF

Info

Publication number: CA2587429C
Authority: CA; Canada
Prior art keywords: alkyl; spp; formula; substituted; compound
Prior art date: 2004-12-07
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

CA2587429A

Other languages

English (en)

French (fr)

Other versions

CA2587429A1 (en

Inventor

Stefan Schnatterer

Michael Maier

Friederike Lochhaas

Werner Knauf

Karl Seeger

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Merial LLC

Original Assignee

Merial LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-12-07

Filing date

2005-12-02

Publication date

2013-03-05

2005-12-02 Application filed by Merial LLC filed Critical Merial LLC

2006-06-15 Publication of CA2587429A1 publication Critical patent/CA2587429A1/en

2013-03-05 Application granted granted Critical

2013-03-05 Publication of CA2587429C publication Critical patent/CA2587429C/en

2025-12-02 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

150000001875 compounds Chemical class 0.000 title claims description 175
230000000361 pesticidal effect Effects 0.000 title claims description 10
JVVRJMXHNUAPHW-UHFFFAOYSA-N 1h-pyrazol-5-amine Chemical class NC=1C=CNN=1 JVVRJMXHNUAPHW-UHFFFAOYSA-N 0.000 title abstract 2
239000000203 mixture Substances 0.000 claims abstract description 108
150000003839 salts Chemical class 0.000 claims abstract description 46
241000607479 Yersinia pestis Species 0.000 claims abstract description 42
238000000034 method Methods 0.000 claims abstract description 39
238000002360 preparation method Methods 0.000 claims abstract description 13
230000008569 process Effects 0.000 claims abstract description 10
-1 NR11R12 Proteins 0.000 claims description 114
125000004169 (C1-C6) alkyl group Chemical group 0.000 claims description 103
229910052736 halogen Inorganic materials 0.000 claims description 40
150000002367 halogens Chemical class 0.000 claims description 40
125000000475 sulfinyl group Chemical group [*:2]S([*:1])=O 0.000 claims description 32
125000000171 (C1-C6) haloalkyl group Chemical group 0.000 claims description 28
125000004178 (C1-C4) alkyl group Chemical group 0.000 claims description 24
125000004191 (C1-C6) alkoxy group Chemical group 0.000 claims description 21
229910052739 hydrogen Inorganic materials 0.000 claims description 21
239000001257 hydrogen Substances 0.000 claims description 21
125000004737 (C1-C6) haloalkoxy group Chemical group 0.000 claims description 20
125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 claims description 20
238000006243 chemical reaction Methods 0.000 claims description 20
239000002585 base Substances 0.000 claims description 19
125000000882 C2-C6 alkenyl group Chemical group 0.000 claims description 18
125000003601 C2-C6 alkynyl group Chemical group 0.000 claims description 18
101100134929 Gallus gallus COR9 gene Proteins 0.000 claims description 16
125000002485 formyl group Chemical group [H]C(*)=O 0.000 claims description 16
125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 15
239000003795 chemical substances by application Substances 0.000 claims description 14
125000000217 alkyl group Chemical group 0.000 claims description 13
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 13
239000004094 surface-active agent Substances 0.000 claims description 11
125000006583 (C1-C3) haloalkyl group Chemical group 0.000 claims description 10
125000006273 (C1-C3) alkyl group Chemical group 0.000 claims description 9
239000003814 drug Substances 0.000 claims description 9
125000000623 heterocyclic group Chemical group 0.000 claims description 9
239000002253 acid Substances 0.000 claims description 8
125000002252 acyl group Chemical group 0.000 claims description 8
229910002091 carbon monoxide Inorganic materials 0.000 claims description 8
CCGKOQOJPYTBIH-UHFFFAOYSA-N ethenone Chemical compound C=C=O CCGKOQOJPYTBIH-UHFFFAOYSA-N 0.000 claims description 8
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UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 6
229910052784 alkaline earth metal Inorganic materials 0.000 claims description 6
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125000006644 (C2-C6) haloalkynyl group Chemical group 0.000 claims description 5
230000010933 acylation Effects 0.000 claims description 5
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125000006413 ring segment Chemical group 0.000 claims description 4
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125000006650 (C2-C4) alkynyl group Chemical group 0.000 claims description 2
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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/44—Oxygen and nitrogen or sulfur and nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

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Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Tropical Medicine & Parasitology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

CA2587429A 2004-12-07 2005-12-02 5-aminopyrazole derivatives as pesticidal compounds Expired - Fee Related CA2587429C (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP04028940.7		2004-12-07
EP04028940		2004-12-07
PCT/EP2005/012903 WO2006061146A1 (en)	2004-12-07	2005-12-02	5-aminopyrazole derivatives as pesticidal compounds

Publications (2)

Publication Number	Publication Date
CA2587429A1 CA2587429A1 (en)	2006-06-15
CA2587429C true CA2587429C (en)	2013-03-05

Family

ID=34927673

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA2587429A Expired - Fee Related CA2587429C (en)	2004-12-07	2005-12-02	5-aminopyrazole derivatives as pesticidal compounds

Country Status (10)

Country	Link
US (1)	US7834003B2 (pt)
EP (1)	EP1828140B1 (pt)
JP (1)	JP5041536B2 (pt)
CN (1)	CN101133033B (pt)
AR (1)	AR052423A1 (pt)
BR (1)	BRPI0518593A2 (pt)
CA (1)	CA2587429C (pt)
ES (1)	ES2454690T3 (pt)
MX (1)	MX2007006715A (pt)
WO (1)	WO2006061146A1 (pt)

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ES2781828T3 (es)	2008-11-19	2020-09-08	Boehringer Ingelheim Animal Health Usa Inc	Composiciones que comprenden un aril pirazol y/o una formamidina, procedimientos y usos de las mismas
UA108641C2 (uk)	2010-04-02	2015-05-25		Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування
CN101836649B (zh) *	2010-05-07	2013-05-15	湖南化工研究院	N-苯基-5-取代氨基吡唑类化合物的制剂及应用
CN104023720B (zh)	2011-11-17	2016-10-26	梅里亚有限公司	包含芳基吡唑和取代咪唑的组合物，其方法和用途
EP2873110B1 (en)	2012-07-13	2016-12-21	Solvay Sa	Fluorinated carbonyl compounds comprising a triple bond, methods for their manufacture and uses thereof
WO2016069983A1 (en)	2014-10-31	2016-05-06	Merial, Inc.	Parasiticidal composition comprising fipronil
BR112018015752A2 (pt)	2016-02-01	2019-01-29	Bayer Animal Health Gmbh	receptor nicotínico de acetilcolina de rhipicephalus e controle de pragas que atua no mesmo
CN120136787A (zh) *	2023-12-13	2025-06-13	青岛清原化合物有限公司	一种吡唑取代的芳基硫化物类化合物及其应用

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US4631211A (en)	1985-03-25	1986-12-23	Scripps Clinic & Research Foundation	Means for sequential solid phase organic synthesis and methods using the same
GB8531485D0 (en)	1985-12-20	1986-02-05	May & Baker Ltd	Compositions of matter
GB8713768D0 (en)	1987-06-12	1987-07-15	May & Baker Ltd	Compositions of matter
DE3606476A1 (de) *	1986-02-28	1987-09-03	Bayer Ag	1-arylpyrazole
US5556873A (en) *	1993-02-24	1996-09-17	Rhone-Poulenc Inc.	Pesticidal 1-aryl-5-(substituted alkyl (thio) amido)pyrazoles
PT839810E (pt) *	1996-11-04	2003-01-31	Bayer Cropscience Sa	1-poliarilpirazois como pesticidas
BRPI0308189B1 (pt) *	2002-03-05	2015-12-29	Bayer Cropscience Sa	derivados de alquilaminopirazol 5-substituídos como pesticidas
MXPA05005900A (es) *	2002-12-03	2005-08-29	Bayer Cropscience Sa	Derivados plaguicidas de 1-aril-3-amidoxima-pirazoles.

2005
- 2005-12-02 MX MX2007006715A patent/MX2007006715A/es active IP Right Grant
- 2005-12-02 ES ES05814293.6T patent/ES2454690T3/es not_active Expired - Lifetime
- 2005-12-02 BR BRPI0518593-9A patent/BRPI0518593A2/pt not_active Application Discontinuation
- 2005-12-02 JP JP2007543786A patent/JP5041536B2/ja not_active Expired - Fee Related
- 2005-12-02 WO PCT/EP2005/012903 patent/WO2006061146A1/en not_active Ceased
- 2005-12-02 CN CN2005800477039A patent/CN101133033B/zh not_active Expired - Fee Related
- 2005-12-02 CA CA2587429A patent/CA2587429C/en not_active Expired - Fee Related
- 2005-12-02 EP EP05814293.6A patent/EP1828140B1/en not_active Expired - Lifetime
- 2005-12-07 AR ARP050105128A patent/AR052423A1/es unknown
2007
- 2007-06-07 US US11/759,386 patent/US7834003B2/en active Active

Also Published As

Publication number	Publication date
CA2587429A1 (en)	2006-06-15
WO2006061146A1 (en)	2006-06-15
EP1828140B1 (en)	2014-03-05
CN101133033A (zh)	2008-02-27
MX2007006715A (es)	2007-08-14
US20080132487A1 (en)	2008-06-05
ES2454690T3 (es)	2014-04-11
US7834003B2 (en)	2010-11-16
CN101133033B (zh)	2013-01-23
AR052423A1 (es)	2007-03-21
EP1828140A1 (en)	2007-09-05
BRPI0518593A2 (pt)	2008-11-25
JP2008522960A (ja)	2008-07-03
JP5041536B2 (ja)	2012-10-03

Legal Events

Date	Code	Title	Description
2010-11-16	EEER	Examination request
2017-01-14	MKLA	Lapsed	Effective date: 20161202

Publication	Publication Date	Title
US20080293824A1 (en)	2008-11-27	Pesticidal substituted piperidines
US20090082389A1 (en)	2009-03-26	Pesticidal substituted piperidines
US7834003B2 (en)	2010-11-16	5-aminopyrazole derivatives as pesticidal compounds
US7678797B2 (en)	2010-03-16	1-phenyl-3-piperazine-pyrazoles and pesticidal compositions of matter thereof
US8097732B2 (en)	2012-01-17	1-arylpyrazoles and their use as pesticide
US20080221109A1 (en)	2008-09-11	Pesticidal substituted thioethers
US7700639B2 (en)	2010-04-20	Chemical compounds, process for their preparation and use thereof