CA2608189A1 - Administration a faible dose d'une composition topique - Google Patents

Administration a faible dose d'une composition topique Download PDF

Info

Publication number: CA2608189A1
Authority: CA; Canada
Prior art keywords: individual; composition; testosterone; active ingredient; delivery
Prior art date: 2005-05-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA002608189A

Other languages

English (en)

Inventor

Thomas Chan

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Macrochem Corp

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-05-11

Filing date

2006-05-04

Publication date

2006-11-23

2006-05-04 Application filed by Individual filed Critical Individual

2006-11-23 Publication of CA2608189A1 publication Critical patent/CA2608189A1/fr

Status Abandoned legal-status Critical Current

Links

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PHTUQLWOUWZIMZ-GZTJUZNOSA-N trans-dothiepin Chemical compound C1SC2=CC=CC=C2C(=C/CCN(C)C)/C2=CC=CC=C21 PHTUQLWOUWZIMZ-GZTJUZNOSA-N 0.000 description 1
229960003741 tranylcypromine Drugs 0.000 description 1
238000011269 treatment regimen Methods 0.000 description 1
229960001332 trenbolone acetate Drugs 0.000 description 1
229960005294 triamcinolone Drugs 0.000 description 1
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229960002117 triamcinolone acetonide Drugs 0.000 description 1
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229960004221 triamcinolone hexacetonide Drugs 0.000 description 1
229960001288 triamterene Drugs 0.000 description 1
CYRMSUTZVYGINF-UHFFFAOYSA-N trichlorofluoromethane Chemical compound FC(Cl)(Cl)Cl CYRMSUTZVYGINF-UHFFFAOYSA-N 0.000 description 1
229940029284 trichlorofluoromethane Drugs 0.000 description 1
239000003029 tricyclic antidepressant agent Substances 0.000 description 1
ZIBGPFATKBEMQZ-UHFFFAOYSA-N triethylene glycol Chemical compound OCCOCCOCCO ZIBGPFATKBEMQZ-UHFFFAOYSA-N 0.000 description 1
229950000451 triflumidate Drugs 0.000 description 1
ZEWQUBUPAILYHI-UHFFFAOYSA-N trifluoperazine Chemical compound C1CN(C)CCN1CCCN1C2=CC(C(F)(F)F)=CC=C2SC2=CC=CC=C21 ZEWQUBUPAILYHI-UHFFFAOYSA-N 0.000 description 1
229960002324 trifluoperazine Drugs 0.000 description 1
229960001032 trihexyphenidyl Drugs 0.000 description 1
QDWJJTJNXAKQKD-UHFFFAOYSA-N trihexyphenidyl hydrochloride Chemical compound Cl.C1CCCCC1C(C=1C=CC=CC=1)(O)CCN1CCCCC1 QDWJJTJNXAKQKD-UHFFFAOYSA-N 0.000 description 1
229940035722 triiodothyronine Drugs 0.000 description 1
CHQOEHPMXSHGCL-UHFFFAOYSA-N trimethaphan Chemical compound C12C[S+]3CCCC3C2N(CC=2C=CC=CC=2)C(=O)N1CC1=CC=CC=C1 CHQOEHPMXSHGCL-UHFFFAOYSA-N 0.000 description 1
229940035742 trimethaphan Drugs 0.000 description 1
IEDVJHCEMCRBQM-UHFFFAOYSA-N trimethoprim Chemical compound COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 IEDVJHCEMCRBQM-UHFFFAOYSA-N 0.000 description 1
229960001082 trimethoprim Drugs 0.000 description 1
229960002431 trimipramine Drugs 0.000 description 1
ZSCDBOWYZJWBIY-UHFFFAOYSA-N trimipramine Chemical compound C1CC2=CC=CC=C2N(CC(CN(C)C)C)C2=CC=CC=C21 ZSCDBOWYZJWBIY-UHFFFAOYSA-N 0.000 description 1
UXQDWARBDDDTKG-UHFFFAOYSA-N tromantadine Chemical compound C1C(C2)CC3CC2CC1(NC(=O)COCCN(C)C)C3 UXQDWARBDDDTKG-UHFFFAOYSA-N 0.000 description 1
229960000832 tromantadine Drugs 0.000 description 1
JFJZZMVDLULRGK-URLMMPGGSA-O tubocurarine Chemical compound C([C@H]1[N+](C)(C)CCC=2C=C(C(=C(OC3=CC=C(C=C3)C[C@H]3C=4C=C(C(=CC=4CCN3C)OC)O3)C=21)O)OC)C1=CC=C(O)C3=C1 JFJZZMVDLULRGK-URLMMPGGSA-O 0.000 description 1
229960001844 tubocurarine Drugs 0.000 description 1
WMPQMBUXZHMEFZ-YJPJVVPASA-N turosteride Chemical compound CN([C@@H]1CC2)C(=O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H](C(=O)N(C(C)C)C(=O)NC(C)C)[C@@]2(C)CC1 WMPQMBUXZHMEFZ-YJPJVVPASA-N 0.000 description 1
229950007816 turosteride Drugs 0.000 description 1
125000005314 unsaturated fatty acid group Chemical group 0.000 description 1
210000002229 urogenital system Anatomy 0.000 description 1
210000004291 uterus Anatomy 0.000 description 1
MSRILKIQRXUYCT-UHFFFAOYSA-M valproate semisodium Chemical compound [Na+].CCCC(C(O)=O)CCC.CCCC(C([O-])=O)CCC MSRILKIQRXUYCT-UHFFFAOYSA-M 0.000 description 1
229960000604 valproic acid Drugs 0.000 description 1
229960003165 vancomycin Drugs 0.000 description 1
MYPYJXKWCTUITO-UHFFFAOYSA-N vancomycin Natural products O1C(C(=C2)Cl)=CC=C2C(O)C(C(NC(C2=CC(O)=CC(O)=C2C=2C(O)=CC=C3C=2)C(O)=O)=O)NC(=O)C3NC(=O)C2NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC(C)C)NC)C(O)C(C=C3Cl)=CC=C3OC3=CC2=CC1=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1 MYPYJXKWCTUITO-UHFFFAOYSA-N 0.000 description 1
MYPYJXKWCTUITO-LYRMYLQWSA-O vancomycin(1+) Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C([O-])=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)[NH2+]C)[C@H]1C[C@](C)([NH3+])[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-O 0.000 description 1
229940124549 vasodilator Drugs 0.000 description 1
239000003071 vasodilator agent Substances 0.000 description 1
BGSZAXLLHYERSY-XQIGCQGXSA-N vecuronium Chemical compound N1([C@@H]2[C@@H](OC(C)=O)C[C@@H]3CC[C@H]4[C@@H]5C[C@@H]([C@@H]([C@]5(CC[C@@H]4[C@@]3(C)C2)C)OC(=O)C)[N+]2(C)CCCCC2)CCCCC1 BGSZAXLLHYERSY-XQIGCQGXSA-N 0.000 description 1
229960003819 vecuronium Drugs 0.000 description 1
239000008158 vegetable oil Substances 0.000 description 1
235000013311 vegetables Nutrition 0.000 description 1
229960001722 verapamil Drugs 0.000 description 1
235000019160 vitamin B3 Nutrition 0.000 description 1
239000011708 vitamin B3 Substances 0.000 description 1
239000008307 w/o/w-emulsion Substances 0.000 description 1
229960005080 warfarin Drugs 0.000 description 1
PJVWKTKQMONHTI-UHFFFAOYSA-N warfarin Chemical compound OC=1C2=CC=CC=C2OC(=O)C=1C(CC(=O)C)C1=CC=CC=C1 PJVWKTKQMONHTI-UHFFFAOYSA-N 0.000 description 1
235000019386 wax ester Nutrition 0.000 description 1
230000003442 weekly effect Effects 0.000 description 1
239000013585 weight reducing agent Substances 0.000 description 1
239000000230 xanthan gum Substances 0.000 description 1
229920001285 xanthan gum Polymers 0.000 description 1
235000010493 xanthan gum Nutrition 0.000 description 1
229940082509 xanthan gum Drugs 0.000 description 1
229940118318 xanthinol Drugs 0.000 description 1
229960000523 zalcitabine Drugs 0.000 description 1
229960002300 zeranol Drugs 0.000 description 1
HBOMLICNUCNMMY-XLPZGREQSA-N zidovudine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 HBOMLICNUCNMMY-XLPZGREQSA-N 0.000 description 1
229960002555 zidovudine Drugs 0.000 description 1
QUEDXNHFTDJVIY-UHFFFAOYSA-N γ-tocopherol Chemical class OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 QUEDXNHFTDJVIY-UHFFFAOYSA-N 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Endocrinology (AREA)
Neurology (AREA)
Nutrition Science (AREA)
Dermatology (AREA)
Diabetes (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Gynecology & Obstetrics (AREA)
Reproductive Health (AREA)
Oil, Petroleum & Natural Gas (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

CA002608189A 2005-05-11 2006-05-04 Administration a faible dose d'une composition topique Abandoned CA2608189A1 (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US67967305P	2005-05-11	2005-05-11
US60/679,673		2005-05-11
PCT/US2006/016831 WO2006124275A2 (fr)	2005-05-11	2006-05-04	Administration a faible dose d'une composition topique

Publications (1)

Publication Number	Publication Date
CA2608189A1 true CA2608189A1 (fr)	2006-11-23

Family

ID=37431780

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002608189A Abandoned CA2608189A1 (fr)	2005-05-11	2006-05-04	Administration a faible dose d'une composition topique

Country Status (7)

Country	Link
EP (1)	EP1879593A2 (fr)
JP (1)	JP2009504566A (fr)
AU (1)	AU2006247934A1 (fr)
CA (1)	CA2608189A1 (fr)
MX (1)	MX2007013912A (fr)
TW (1)	TW200722092A (fr)
WO (1)	WO2006124275A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP6863832B2 (ja) *	2016-07-21	2021-04-21	日清ファルマ株式会社	筋萎縮抑制用組成物
US20230041289A1 (en) *	2021-08-05	2023-02-09	Innovus Pharmaceuticals, Inc.	Compositions and methods for enhancing or treating female sexual response

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4861764A (en) *	1986-11-17	1989-08-29	Macro Chem. Corp.	Percutaneous absorption enhancers, compositions containing same and method of use
US5849729A (en) *	1995-12-26	1998-12-15	Hershey Foods Corporation	Use of hydrolyzed cocoa butter for percutaneous absorption

2006
- 2006-05-04 MX MX2007013912A patent/MX2007013912A/es not_active Application Discontinuation
- 2006-05-04 WO PCT/US2006/016831 patent/WO2006124275A2/fr not_active Ceased
- 2006-05-04 EP EP06758933A patent/EP1879593A2/fr not_active Withdrawn
- 2006-05-04 JP JP2008511171A patent/JP2009504566A/ja active Pending
- 2006-05-04 AU AU2006247934A patent/AU2006247934A1/en not_active Abandoned
- 2006-05-04 CA CA002608189A patent/CA2608189A1/fr not_active Abandoned
- 2006-05-05 TW TW095116143A patent/TW200722092A/zh unknown

Also Published As

Publication number	Publication date
EP1879593A2 (fr)	2008-01-23
AU2006247934A1 (en)	2006-11-23
JP2009504566A (ja)	2009-02-05
WO2006124275A3 (fr)	2009-04-09
TW200722092A (en)	2007-06-16
MX2007013912A (es)	2008-03-25
WO2006124275A2 (fr)	2006-11-23

Legal Events

Date	Code	Title	Description
2010-05-04	FZDE	Dead

Publication	Publication Date	Title
US9180194B2 (en)	2015-11-10	Method and composition for transdermal drug delivery
US6299900B1 (en)	2001-10-09	Dermal penetration enhancers and drug delivery systems involving same
US20070190019A1 (en)	2007-08-16	Compositions and methods for topical administration
WO2009036311A1 (fr)	2009-03-19	Compositions pharmaceutiques transdermiques sans alcool
WO2005056103A1 (fr)	2005-06-23	Methode de traitement d'un effet indesirable suite a la liberation d'un medicament au niveau transdermique ou topique
CA2610708C (fr)	2013-10-08	Methode et composition pour l'administration transdermique d'un medicament
CA2608189A1 (fr)	2006-11-23	Administration a faible dose d'une composition topique
AU2011202787B2 (en)	2013-02-21	Method and composition for transdermal drug delivery
AU2006254742B2 (en)	2011-03-10	Method and composition for transdermal drug delivery
HK1115300B (en)	2017-09-15	Method and composition for testosterone transdermal delivery
HK1115300A (en)	2008-11-28	Method and composition for testosterone transdermal delivery