CA2616832A1 - Adaptateur d'alignement a utiliser avec un generateur de radio-isotopes et procedes d'utilisation dudit adaptateur d'alignement - Google Patents
Adaptateur d'alignement a utiliser avec un generateur de radio-isotopes et procedes d'utilisation dudit adaptateur d'alignement Download PDFInfo
- Publication number
- CA2616832A1 CA2616832A1 CA002616832A CA2616832A CA2616832A1 CA 2616832 A1 CA2616832 A1 CA 2616832A1 CA 002616832 A CA002616832 A CA 002616832A CA 2616832 A CA2616832 A CA 2616832A CA 2616832 A1 CA2616832 A1 CA 2616832A1
- Authority
- CA
- Canada
- Prior art keywords
- alignment
- passage
- container
- radioisotope generator
- adapter
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000000034 method Methods 0.000 title claims abstract description 24
- 238000010828 elution Methods 0.000 claims abstract description 109
- 229940121896 radiopharmaceutical Drugs 0.000 claims description 26
- 239000012217 radiopharmaceutical Substances 0.000 claims description 26
- 230000002799 radiopharmaceutical effect Effects 0.000 claims description 26
- 230000000153 supplemental effect Effects 0.000 claims description 23
- 239000012530 fluid Substances 0.000 claims description 21
- 230000005855 radiation Effects 0.000 claims description 21
- 230000002285 radioactive effect Effects 0.000 claims description 9
- 239000000463 material Substances 0.000 claims description 8
- 238000003860 storage Methods 0.000 claims description 3
- 230000008878 coupling Effects 0.000 claims 1
- 238000010168 coupling process Methods 0.000 claims 1
- 238000005859 coupling reaction Methods 0.000 claims 1
- 238000012512 characterization method Methods 0.000 abstract 1
- 238000003780 insertion Methods 0.000 description 17
- 230000037431 insertion Effects 0.000 description 17
- 238000009206 nuclear medicine Methods 0.000 description 17
- 238000003384 imaging method Methods 0.000 description 10
- 210000000056 organ Anatomy 0.000 description 10
- 230000008569 process Effects 0.000 description 10
- 239000003795 chemical substances by application Substances 0.000 description 9
- 239000012857 radioactive material Substances 0.000 description 9
- 238000013461 design Methods 0.000 description 7
- GKLVYJBZJHMRIY-OUBTZVSYSA-N Technetium-99 Chemical compound [99Tc] GKLVYJBZJHMRIY-OUBTZVSYSA-N 0.000 description 6
- 229940056501 technetium 99m Drugs 0.000 description 6
- 206010028980 Neoplasm Diseases 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 5
- 239000012141 concentrate Substances 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 230000007246 mechanism Effects 0.000 description 4
- ZOKXTWBITQBERF-AKLPVKDBSA-N Molybdenum Mo-99 Chemical compound [99Mo] ZOKXTWBITQBERF-AKLPVKDBSA-N 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 201000011510 cancer Diseases 0.000 description 3
- 238000009434 installation Methods 0.000 description 3
- 230000003993 interaction Effects 0.000 description 3
- 229950009740 molybdenum mo-99 Drugs 0.000 description 3
- 239000004033 plastic Substances 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- WFKWXMTUELFFGS-UHFFFAOYSA-N tungsten Chemical compound [W] WFKWXMTUELFFGS-UHFFFAOYSA-N 0.000 description 3
- 229910052721 tungsten Inorganic materials 0.000 description 3
- 239000010937 tungsten Substances 0.000 description 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000001575 pathological effect Effects 0.000 description 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 1
- -1 Indium-113m Chemical compound 0.000 description 1
- SIJNDWFHVBDXDY-IEOVAKBOSA-N [hydroxy(phosphono)methyl]phosphonic acid;technetium-99 Chemical compound [99Tc].OP(=O)(O)C(O)P(O)(O)=O SIJNDWFHVBDXDY-IEOVAKBOSA-N 0.000 description 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 229940127043 diagnostic radiopharmaceutical Drugs 0.000 description 1
- 238000010494 dissociation reaction Methods 0.000 description 1
- 230000005593 dissociations Effects 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 229910052740 iodine Inorganic materials 0.000 description 1
- 239000011630 iodine Substances 0.000 description 1
- 239000011133 lead Substances 0.000 description 1
- 239000006193 liquid solution Substances 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 230000013011 mating Effects 0.000 description 1
- 239000002991 molded plastic Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 230000006335 response to radiation Effects 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- CIOAGBVUUVVLOB-BJUDXGSMSA-N strontium-87 Chemical compound [87Sr] CIOAGBVUUVVLOB-BJUDXGSMSA-N 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000011287 therapeutic dose Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 210000001685 thyroid gland Anatomy 0.000 description 1
Classifications
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
- G21G4/00—Radioactive sources
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21F—PROTECTION AGAINST X-RADIATION, GAMMA RADIATION, CORPUSCULAR RADIATION OR PARTICLE BOMBARDMENT; TREATING RADIOACTIVELY CONTAMINATED MATERIAL; DECONTAMINATION ARRANGEMENTS THEREFOR
- G21F5/00—Transportable or portable shielded containers
- G21F5/015—Transportable or portable shielded containers for storing radioactive sources, e.g. source carriers for irradiation units; Radioisotope containers
Landscapes
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- High Energy & Nuclear Physics (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Radiation-Therapy Devices (AREA)
Abstract
La présente invention peut être caractérisée, entre autres, par le fait qu'elle concerne un adaptateur d'alignement qui peut être utilisé dans des procédures d'élution de radio-isotopes. Dans certains modes de réalisation, l'adaptateur d'alignement peut être utilisé au moins pour aider à aligner divers composants d'un système d'élution. Par exemple, dans certains modes de réalisation, l'adaptateur d'alignement peut être utilisé pour aider à aligner au moins d'une manière générale une ouverture définie dans un couvercle du système d'élution et une aiguille d'élution d'un générateur de radio-isotopes. Dans certains modes de réalisation, l'adaptateur d'alignement peut être utilisé pour aider à aligner au moins d'une manière générale un ensemble d'élution (par exemple un blindage d'élution abritant un flacon d'éluat) et une aiguille d'élution d'un générateur de radio-isotopes. En outre, dans certains modes de réalisation, l'adaptateur d'alignement peut être utilisé pour aider à aligner au moins d'une manière générale un récipient d'éluant (par exemple une bouteille d'éluant) et une aiguille d'un générateur de radio-isotopes.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70303605P | 2005-07-27 | 2005-07-27 | |
| US60/703,036 | 2005-07-27 | ||
| PCT/US2006/029057 WO2007016172A2 (fr) | 2005-07-27 | 2006-07-26 | Adaptateur d'alignement à utiliser avec un générateur de radio-isotopes et procédés d'utilisation dudit adaptateur d'alignement |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2616832A1 true CA2616832A1 (fr) | 2007-02-08 |
Family
ID=37607205
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002616832A Abandoned CA2616832A1 (fr) | 2005-07-27 | 2006-07-26 | Adaptateur d'alignement a utiliser avec un generateur de radio-isotopes et procedes d'utilisation dudit adaptateur d'alignement |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20080203318A1 (fr) |
| EP (1) | EP1913602A2 (fr) |
| JP (1) | JP2009503516A (fr) |
| CN (1) | CN101233582A (fr) |
| AU (1) | AU2006275887A1 (fr) |
| CA (1) | CA2616832A1 (fr) |
| IL (1) | IL188951A0 (fr) |
| WO (1) | WO2007016172A2 (fr) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101253577A (zh) * | 2005-08-29 | 2008-08-27 | 马林克罗特公司 | 用于将放射性同位素洗提到设置在放射性同位素发生器组件之外的容器的系统和方法 |
| CA2665193C (fr) * | 2006-10-06 | 2016-02-09 | Mallinckrodt Inc. | Systeme d'elution de radioisotopes a auto-alignement |
| US8317674B2 (en) | 2008-06-11 | 2012-11-27 | Bracco Diagnostics Inc. | Shielding assemblies for infusion systems |
| CA2724669C (fr) | 2008-06-11 | 2016-01-12 | Bracco Diagnostics Inc. | Configurations de structure en coffret pour systemes de perfusion |
| NZ597070A (en) * | 2009-05-13 | 2013-03-28 | Lantheus Medical Imaging Inc | Radionuclide generator designed to prevent excess liquid from being introduced during sterilisation |
| US9153350B2 (en) | 2011-01-19 | 2015-10-06 | Mallinckrodt Llc | Protective shroud for nuclear pharmacy generators |
| US8809804B2 (en) * | 2011-01-19 | 2014-08-19 | Mallinckrodt Llc | Holder and tool for radioisotope elution system |
| US8866104B2 (en) | 2011-01-19 | 2014-10-21 | Mallinckrodt Llc | Radioisotope elution system |
| RU2741629C2 (ru) | 2016-09-20 | 2021-01-28 | Бракко Дайэгностикс Инк. | Системы и способы производства, инфузионного ввода и контроля доставки радиоактивного изотопа |
| US12170153B2 (en) | 2018-03-28 | 2024-12-17 | Bracco Diagnostics Inc. | Systems and techniques for calibrating radioisotope delivery systems with a gamma detector |
| SG11202009326XA (en) | 2018-03-28 | 2020-10-29 | Bracco Diagnostics Inc | Early detection of radioisotope generator end life |
| CN115104159A (zh) | 2020-02-21 | 2022-09-23 | 布拉科诊断公司 | 放射性同位素发生器早期突破检测 |
| WO2022170600A1 (fr) * | 2021-02-10 | 2022-08-18 | 西安大医集团股份有限公司 | Cylindre de blindage de tube accélérateur, tête de traitement d'accélérateur et appareil de radiothérapie |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3446965A (en) * | 1966-08-10 | 1969-05-27 | Mallinckrodt Chemical Works | Generation and containerization of radioisotopes |
| US3535085A (en) * | 1967-08-07 | 1970-10-20 | Mallinckrodt Chemical Works | Closed system generation and containerization of radioisotopes |
| US3783291A (en) * | 1968-11-25 | 1974-01-01 | Squibb & Sons Inc | Sterile generator housing and support |
| US3655981A (en) * | 1968-11-29 | 1972-04-11 | Mallinckrodt Chemical Works | Closed system generation and containerization of radioisotopes for eluting a daughter radioisotope from a parent radioisotope |
| US3710118A (en) * | 1970-05-25 | 1973-01-09 | Mallinckrodt Chemical Works | Radioisotope generator |
| US3774035A (en) * | 1971-07-12 | 1973-11-20 | New England Nuclear Corp | Method and system for generating and collecting a radionuclide eluate |
| US3814941A (en) * | 1972-10-24 | 1974-06-04 | Squibb & Sons Inc | Loading syringe for use with radioactive solutions and other non-sterile solutions |
| US3801818A (en) * | 1972-10-24 | 1974-04-02 | Squibb & Sons Inc | Radioactive generator with permeable closure |
| US3920995A (en) * | 1973-05-04 | 1975-11-18 | Squibb & Sons Inc | Radioactive material generator |
| US3946238A (en) * | 1974-08-05 | 1976-03-23 | Chevron Research Company | Shielded radioisotope generator and method for using same |
| US4039835A (en) * | 1976-03-12 | 1977-08-02 | Colombetti Lelio G | Reloadable radioactive generator system |
| DE2712635C2 (de) * | 1977-03-23 | 1982-04-29 | Hoechst Ag, 6000 Frankfurt | Nuklidgenerator zur Herstellung von Radionukliden |
| US4160910A (en) * | 1977-06-20 | 1979-07-10 | Union Carbide Corporation | Rechargeable 99MO/99MTC generator system |
| US4206358A (en) * | 1977-10-19 | 1980-06-03 | Australian Atomic Energy Commission | Technetium-99 generators |
| DE2800496C2 (de) * | 1978-01-05 | 1987-02-12 | Chemische Fabrik von Heyden GmbH, 8000 München | Radionuklidgenerator |
| NL190345C (nl) * | 1978-10-20 | 1994-01-17 | Mallinckrodt Diagnostica Bv | Afscherminrichting voor een radioisotopen producerende generator. |
| NL7902342A (nl) * | 1979-03-26 | 1980-09-30 | Byk Mallinckrodt Cil Bv | Isotopengenerator. |
| FR2455334A1 (fr) * | 1979-04-24 | 1980-11-21 | Commissariat Energie Atomique | Procede de preparation d'une solution de gallium 68 sous forme ionique |
| US4296785A (en) * | 1979-07-09 | 1981-10-27 | Mallinckrodt, Inc. | System for generating and containerizing radioisotopes |
| DE8621529U1 (de) * | 1986-08-11 | 1986-10-30 | Von Heyden GmbH, 8000 München | Dosiervorrichtung für Radionuklidgeneratoren |
| US4833329A (en) * | 1987-11-20 | 1989-05-23 | Mallinckrodt, Inc. | System for generating and containerizing radioisotopes |
| US5109160A (en) * | 1990-10-12 | 1992-04-28 | E. I. Du Pont De Nemours And Company | Sterilizable radionuclide generator and method for sterilizing the same |
| JP3540497B2 (ja) * | 1995-04-20 | 2004-07-07 | 日本メジフィジックス株式会社 | 放射性物質用遮蔽部材の製造方法 |
| US6157036A (en) * | 1998-12-02 | 2000-12-05 | Cedars-Sinai Medical Center | System and method for automatically eluting and concentrating a radioisotope |
| GB2386742B (en) * | 2002-03-20 | 2004-02-11 | Amersham Plc | Radioisotope generator component support |
-
2006
- 2006-07-26 AU AU2006275887A patent/AU2006275887A1/en not_active Abandoned
- 2006-07-26 CA CA002616832A patent/CA2616832A1/fr not_active Abandoned
- 2006-07-26 US US11/995,721 patent/US20080203318A1/en not_active Abandoned
- 2006-07-26 CN CNA2006800275332A patent/CN101233582A/zh active Pending
- 2006-07-26 WO PCT/US2006/029057 patent/WO2007016172A2/fr not_active Ceased
- 2006-07-26 EP EP06788575A patent/EP1913602A2/fr not_active Withdrawn
- 2006-07-26 JP JP2008524114A patent/JP2009503516A/ja active Pending
-
2008
- 2008-01-22 IL IL188951A patent/IL188951A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2006275887A1 (en) | 2007-02-08 |
| WO2007016172A2 (fr) | 2007-02-08 |
| WO2007016172A3 (fr) | 2007-06-21 |
| JP2009503516A (ja) | 2009-01-29 |
| CN101233582A (zh) | 2008-07-30 |
| IL188951A0 (en) | 2008-04-13 |
| EP1913602A2 (fr) | 2008-04-23 |
| US20080203318A1 (en) | 2008-08-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued | ||
| FZDE | Discontinued |
Effective date: 20110726 |