CA2633515C - Compositions et procedes pour le traitement dermique de la douleur - Google Patents

Compositions et procedes pour le traitement dermique de la douleur Download PDF

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Publication number
CA2633515C
CA2633515C CA2633515A CA2633515A CA2633515C CA 2633515 C CA2633515 C CA 2633515C CA 2633515 A CA2633515 A CA 2633515A CA 2633515 A CA2633515 A CA 2633515A CA 2633515 C CA2633515 C CA 2633515C
Authority
CA
Canada
Prior art keywords
formulation
volatile solvent
pain
drug
solvent system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2633515A
Other languages
English (en)
Other versions
CA2633515A1 (fr
Inventor
Jie Zhang
Sanjay Sharma
Kevin S. Warner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nuvo Research Inc
Original Assignee
ZARS Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ZARS Pharma Inc filed Critical ZARS Pharma Inc
Priority to CA2747845A priority Critical patent/CA2747845C/fr
Publication of CA2633515A1 publication Critical patent/CA2633515A1/fr
Application granted granted Critical
Publication of CA2633515C publication Critical patent/CA2633515C/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2633515A 2005-12-14 2006-12-14 Compositions et procedes pour le traitement dermique de la douleur Expired - Fee Related CA2633515C (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2747845A CA2747845C (fr) 2005-12-14 2006-12-14 Compositions et procedes pour le traitement dermique de la douleur

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US75063705P 2005-12-14 2005-12-14
US75051905P 2005-12-14 2005-12-14
US75068305P 2005-12-14 2005-12-14
US60/750,683 2005-12-14
US60/750,637 2005-12-14
US60/750,519 2005-12-14
PCT/US2006/047926 WO2007070679A2 (fr) 2005-12-14 2006-12-14 Compositions et procedes pour le traitement dermique de la douleur

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2747845A Division CA2747845C (fr) 2005-12-14 2006-12-14 Compositions et procedes pour le traitement dermique de la douleur

Publications (2)

Publication Number Publication Date
CA2633515A1 CA2633515A1 (fr) 2007-06-21
CA2633515C true CA2633515C (fr) 2011-10-18

Family

ID=38163542

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2633515A Expired - Fee Related CA2633515C (fr) 2005-12-14 2006-12-14 Compositions et procedes pour le traitement dermique de la douleur

Country Status (5)

Country Link
EP (1) EP1959931A4 (fr)
JP (1) JP2009524586A (fr)
AU (1) AU2006326018B2 (fr)
CA (1) CA2633515C (fr)
WO (1) WO2007070679A2 (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8907153B2 (en) 2004-06-07 2014-12-09 Nuvo Research Inc. Adhesive peel-forming formulations for dermal delivery of drugs and methods of using the same
US8741332B2 (en) 2004-06-07 2014-06-03 Nuvo Research Inc. Compositions and methods for dermally treating neuropathic pain
US8741333B2 (en) 2004-06-07 2014-06-03 Nuvo Research Inc. Compositions and methods for treating dermatitis or psoriasis
US9283177B2 (en) * 2007-01-16 2016-03-15 Juventio, Llc Topical anesthetic for rapid local anesthesia and method of applying a topical anesthetic
WO2008089242A1 (fr) 2007-01-16 2008-07-24 Dermworx, Incorporated Anesthésique topique pour anesthésie locale rapide et méthode d'application d'un anesthésique topique
CN101970427A (zh) 2008-02-29 2011-02-09 Vm生物医药公司 治疗疼痛症状及其它失调的方法
CA2730787A1 (fr) * 2008-07-16 2010-01-21 David M. Cohen Systeme d'apport de medicament topique
US9012477B2 (en) * 2009-01-06 2015-04-21 Nuvo Research Inc. Method of treating neuropathic pain
US20110086913A1 (en) * 2009-04-01 2011-04-14 Jie Zhang Methods for treating myofascial, muscle, and/or back pain
CN102427792A (zh) 2009-05-04 2012-04-25 扎斯制药公司 治疗与神经瘤、神经卡压及其他病况相关联的疼痛的方法
US9186334B2 (en) 2009-05-04 2015-11-17 Nuvo Research Inc. Heat assisted lidocaine and tetracaine for transdermal analgesia
CN102834096A (zh) 2010-01-14 2012-12-19 卢福研究公司 用于疼痛控制的固态成型局部麻醉制剂
US20130324502A1 (en) 2011-02-10 2013-12-05 Moberg Pharma Ab Novel formulations for dermal, transdermal and mucosal use 1
BR112013028802B1 (pt) 2011-05-10 2021-10-26 Itochu Chemical Frontier Corporation Curativo adesivo não-aquoso
ES3034911T3 (en) 2011-05-10 2025-08-26 Itochu Chemical Frontier Corp Non-aqueous patch
US11786455B2 (en) 2011-05-10 2023-10-17 Itochu Chemical Frontier Corporation Non-aqueous patch
CN103533927A (zh) * 2011-05-26 2014-01-22 诺瓦提斯公司 用于生理学活性成分经皮给药的组合物
CN102302418B (zh) * 2011-09-21 2013-01-23 韩褆 节水型多功能洗手消毒液
LT2823815T (lt) 2011-09-27 2018-08-27 Itochu Chemical Frontier Corporation Nevandeninis pleistras
CN103142458B (zh) * 2013-01-22 2015-09-09 莱普德制药有限公司 无成瘾性镇痛缓释递药系统的组方与制备方法
GB201317718D0 (en) * 2013-10-07 2013-11-20 Buzzz Pharmaceuticals Ltd Novel formulation
JP6209749B2 (ja) * 2015-12-10 2017-10-11 伊藤忠ケミカルフロンティア株式会社 非水性貼付剤
US11141387B2 (en) 2017-01-05 2021-10-12 Medrx Co., Ltd. Memantine-containing transdermally absorbable liquid
EP3720417B1 (fr) 2017-12-04 2023-11-01 Johnson & Johnson Consumer Inc. Composition d'émulsion topique contenant un médicament anti-inflammatoire non stéroïdien
WO2022167359A1 (fr) * 2021-02-02 2022-08-11 DuPont Nutrition USA, Inc. Composition de gel aqueux comprenant une éthylcellulose

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPN814496A0 (en) * 1996-02-19 1996-03-14 Monash University Dermal penetration enhancer
US20040018241A1 (en) * 1997-09-26 2004-01-29 Noven Pharmaceuticals, Inc. Bioadhesive compositions and methods for topical administration of active agents
IL135258A0 (en) * 1997-09-26 2001-05-20 Noven Pharma Bioadhesive compositions and methods for topical administration of active agents
US6528086B2 (en) * 1999-09-28 2003-03-04 Zars, Inc. Methods and apparatus for drug delivery involving phase changing formulations
AUPQ419099A0 (en) * 1999-11-23 1999-12-16 Ko, Thomas Sai Ying Novel compositions and methods
US6432415B1 (en) * 1999-12-17 2002-08-13 Axrix Laboratories, Inc. Pharmaceutical gel and aerosol formulations and methods to administer the same to skin and mucosal surfaces

Also Published As

Publication number Publication date
EP1959931A2 (fr) 2008-08-27
EP1959931A4 (fr) 2012-08-22
WO2007070679A2 (fr) 2007-06-21
WO2007070679A3 (fr) 2009-01-08
AU2006326018A1 (en) 2007-06-21
AU2006326018B2 (en) 2013-04-18
JP2009524586A (ja) 2009-07-02
CA2633515A1 (fr) 2007-06-21

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20161214