CA2682994A1 - Heterocyclic compounds with affinity to muscarinic receptors - Google Patents
Heterocyclic compounds with affinity to muscarinic receptors Download PDFInfo
- Publication number
- CA2682994A1 CA2682994A1 CA002682994A CA2682994A CA2682994A1 CA 2682994 A1 CA2682994 A1 CA 2682994A1 CA 002682994 A CA002682994 A CA 002682994A CA 2682994 A CA2682994 A CA 2682994A CA 2682994 A1 CA2682994 A1 CA 2682994A1
- Authority
- CA
- Canada
- Prior art keywords
- pyrazol
- compound
- tetrahydro
- methylpyridine
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Psychiatry (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91358407P | 2007-04-24 | 2007-04-24 | |
| EP07106814.2 | 2007-04-24 | ||
| EP07106814 | 2007-04-24 | ||
| US60/913,584 | 2007-04-24 | ||
| PCT/EP2008/054897 WO2008129054A2 (en) | 2007-04-24 | 2008-04-23 | Heterocyclic compounds with affinity to muscarinic receptors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2682994A1 true CA2682994A1 (en) | 2008-10-30 |
Family
ID=38510408
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002682994A Abandoned CA2682994A1 (en) | 2007-04-24 | 2008-04-23 | Heterocyclic compounds with affinity to muscarinic receptors |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP2150543A2 (de) |
| JP (1) | JP2010525020A (de) |
| CN (1) | CN101939311A (de) |
| AU (1) | AU2008240704A1 (de) |
| CA (1) | CA2682994A1 (de) |
| MX (1) | MX2009011499A (de) |
| RU (1) | RU2446166C2 (de) |
| WO (1) | WO2008129054A2 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8084473B2 (en) | 2007-04-24 | 2011-12-27 | Solvay Pharmaceuticals B.V. | Heterocyclic compounds with affinity to muscarinic receptors |
| CN102459175A (zh) * | 2009-05-07 | 2012-05-16 | 托蓝特医药公司 | 用于治疗糖尿病的哌啶衍生物 |
| JP5996532B2 (ja) | 2010-07-15 | 2016-09-21 | バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ ＧｍｂＨ | 有害生物防除剤としての新規複素環式化合物 |
| CA2880326A1 (en) * | 2012-10-26 | 2014-05-01 | F. Hoffmann-La Roche Ag | 3,4-disubstituted 1 h-pyrazole and 4,5-disubstituted thiazole inhibitors of syk cap |
| AR121893A1 (es) | 2020-04-22 | 2022-07-20 | Sumitomo Chemical Co | Compuesto de fenilo y método para controlar enfermedades vegetales |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL83275A (en) * | 1986-09-08 | 1994-02-27 | Novo Nordisk As | Substituted 1, 2, 4- oxadiazolyl piperidine compounds, their preparation and pharmaceutical compositions containing them |
| GB8714789D0 (en) * | 1987-06-24 | 1987-07-29 | Lundbeck & Co As H | Heterocyclic compounds |
| IL88156A (en) * | 1987-11-13 | 1997-02-18 | Novo Nordisk As | Azacyclic compounds their preparation and pharmaceutical compositions containing them |
| WO1999062885A1 (en) * | 1998-06-05 | 1999-12-09 | Boehringer Ingelheim Pharmaceuticals, Inc. | Substituted 1-(4-aminophenyl)pyrazoles and their use as anti-inflammatory agents |
| CN1571787A (zh) * | 2001-10-17 | 2005-01-26 | Ucb公司 | 奎宁环衍生物、制备它们的方法和它们作为m2和/或m3毒蕈碱受体抑制剂的用途 |
| US6861440B2 (en) * | 2001-10-26 | 2005-03-01 | Hoffmann-La Roche Inc. | DPP IV inhibitors |
| WO2006070198A1 (en) * | 2004-12-30 | 2006-07-06 | Astex Therapeutics Limited | Pyrazole derivatives as that modulate the activity of cdk, gsk and aurora kinases |
-
2008
- 2008-04-23 AU AU2008240704A patent/AU2008240704A1/en not_active Abandoned
- 2008-04-23 RU RU2009143353/04A patent/RU2446166C2/ru not_active IP Right Cessation
- 2008-04-23 CA CA002682994A patent/CA2682994A1/en not_active Abandoned
- 2008-04-23 EP EP08759382A patent/EP2150543A2/de not_active Withdrawn
- 2008-04-23 JP JP2010504671A patent/JP2010525020A/ja not_active Withdrawn
- 2008-04-23 MX MX2009011499A patent/MX2009011499A/es not_active Application Discontinuation
- 2008-04-23 CN CN2008800165261A patent/CN101939311A/zh active Pending
- 2008-04-23 WO PCT/EP2008/054897 patent/WO2008129054A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU2008240704A1 (en) | 2008-10-30 |
| WO2008129054A2 (en) | 2008-10-30 |
| WO2008129054A3 (en) | 2009-02-05 |
| RU2446166C2 (ru) | 2012-03-27 |
| EP2150543A2 (de) | 2010-02-10 |
| JP2010525020A (ja) | 2010-07-22 |
| RU2009143353A (ru) | 2011-05-27 |
| CN101939311A (zh) | 2011-01-05 |
| MX2009011499A (es) | 2009-11-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Dead |
Effective date: 20140423 |