CA2683754A1 - Traitement du syndrome de down au moyen d'antagonistes des recepteurs des benzodiazepines - Google Patents
Traitement du syndrome de down au moyen d'antagonistes des recepteurs des benzodiazepines Download PDFInfo
- Publication number
- CA2683754A1 CA2683754A1 CA002683754A CA2683754A CA2683754A1 CA 2683754 A1 CA2683754 A1 CA 2683754A1 CA 002683754 A CA002683754 A CA 002683754A CA 2683754 A CA2683754 A CA 2683754A CA 2683754 A1 CA2683754 A1 CA 2683754A1
- Authority
- CA
- Canada
- Prior art keywords
- composition
- benzodiazepine
- active pharmaceutical
- pharmaceutical ingredient
- flumazenil
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
- A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91125407P | 2007-04-11 | 2007-04-11 | |
| US60/911,254 | 2007-04-11 | ||
| PCT/US2008/060133 WO2008128116A1 (fr) | 2007-04-11 | 2008-04-11 | Traitement du syndrome de down au moyen d'antagonistes des récepteurs des benzodiazépines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2683754A1 true CA2683754A1 (fr) | 2008-10-23 |
Family
ID=39864354
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002683754A Abandoned CA2683754A1 (fr) | 2007-04-11 | 2008-04-11 | Traitement du syndrome de down au moyen d'antagonistes des recepteurs des benzodiazepines |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP2146576A4 (fr) |
| JP (1) | JP2010523716A (fr) |
| AU (1) | AU2008240148B2 (fr) |
| CA (1) | CA2683754A1 (fr) |
| WO (1) | WO2008128116A1 (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2678320B1 (fr) | 2011-02-23 | 2018-09-19 | Coeruleus Ltd. | Complexes de flumazénil, compositions les comprenant et leurs utilisations |
| US20220354807A1 (en) * | 2019-09-30 | 2022-11-10 | Xiamen University | Use of valeric acid derivative in treatment of down's syndrome |
| GB202413915D0 (en) * | 2024-09-20 | 2024-11-06 | Fitabeo Therapeutics Ltd | treatment of drug use |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6297256B1 (en) * | 1999-06-15 | 2001-10-02 | Neurogen Corporation | Aryl and heteroaryl substituted pyridino derivatives GABA brain receptor ligands |
| WO2005012306A2 (fr) * | 2003-07-25 | 2005-02-10 | Neurogen Corporation | Imidazo-pyrimidines et triazolo-pyrimidines: ligands de recepteur de benzodiazepine |
| JP2009507081A (ja) * | 2005-09-07 | 2009-02-19 | ブレインセルス，インコーポレイティド | ＨＤａｃ阻害による神経発生の調整 |
-
2008
- 2008-04-11 EP EP08745691A patent/EP2146576A4/fr not_active Withdrawn
- 2008-04-11 CA CA002683754A patent/CA2683754A1/fr not_active Abandoned
- 2008-04-11 AU AU2008240148A patent/AU2008240148B2/en not_active Expired - Fee Related
- 2008-04-11 JP JP2010503256A patent/JP2010523716A/ja active Pending
- 2008-04-11 WO PCT/US2008/060133 patent/WO2008128116A1/fr not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP2146576A1 (fr) | 2010-01-27 |
| JP2010523716A (ja) | 2010-07-15 |
| EP2146576A4 (fr) | 2013-01-16 |
| AU2008240148A1 (en) | 2008-10-23 |
| AU2008240148B2 (en) | 2012-09-27 |
| WO2008128116A1 (fr) | 2008-10-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Dead |
Effective date: 20130805 |