CA2685214C - Forme posologique orale a liberation regulee amelioree - Google Patents
Forme posologique orale a liberation regulee amelioree Download PDFInfo
- Publication number
- CA2685214C CA2685214C CA2685214A CA2685214A CA2685214C CA 2685214 C CA2685214 C CA 2685214C CA 2685214 A CA2685214 A CA 2685214A CA 2685214 A CA2685214 A CA 2685214A CA 2685214 C CA2685214 C CA 2685214C
- Authority
- CA
- Canada
- Prior art keywords
- composition
- bupropion
- cellulose
- polymer
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- 230000005586 smoking cessation Effects 0.000 description 1
- 229940124535 smoking cessation aid Drugs 0.000 description 1
- 230000000391 smoking effect Effects 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 230000009747 swallowing Effects 0.000 description 1
- 230000001839 systemic circulation Effects 0.000 description 1
- 239000007916 tablet composition Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000012956 testing procedure Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 229960002622 triacetin Drugs 0.000 description 1
- WEAPVABOECTMGR-UHFFFAOYSA-N triethyl 2-acetyloxypropane-1,2,3-tricarboxylate Chemical compound CCOC(=O)CC(C(=O)OCC)(OC(C)=O)CC(=O)OCC WEAPVABOECTMGR-UHFFFAOYSA-N 0.000 description 1
- 239000001069 triethyl citrate Substances 0.000 description 1
- VMYFZRTXGLUXMZ-UHFFFAOYSA-N triethyl citrate Natural products CCOC(=O)C(O)(C(=O)OCC)C(=O)OCC VMYFZRTXGLUXMZ-UHFFFAOYSA-N 0.000 description 1
- 235000013769 triethyl citrate Nutrition 0.000 description 1
- 125000005591 trimellitate group Chemical group 0.000 description 1
- 229920003169 water-soluble polymer Polymers 0.000 description 1
- 230000004584 weight gain Effects 0.000 description 1
- 235000019786 weight gain Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Addiction (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
Abstract
Composition pharmaceutique conçue pour le dosage quotidien du bupropion, qui comprend (A) une forme à libération soutenue avec (i) une base de bupropion ou d'un sel acceptable du point de vue pharmaceutique ou un stéréoisomère de celui-ci et (ii) un composé à libération soutenue et (B) une forme à libération immédiate du bupropion ou d'un sel acceptable du point de vue pharmaceutique ou un stéréoisomère de celui-ci.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA2796884A CA2796884A1 (fr) | 2001-02-08 | 2002-02-08 | Forme posologique orale a liberation regulee amelioree |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26745601P | 2001-02-08 | 2001-02-08 | |
| US26745701P | 2001-02-08 | 2001-02-08 | |
| US60/267,456 | 2001-02-08 | ||
| US60/267,457 | 2001-02-08 | ||
| CA2433915A CA2433915C (fr) | 2001-02-08 | 2002-02-08 | Forme posologique orale a liberation regulee amelioree |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2433915A Division CA2433915C (fr) | 2001-02-08 | 2002-02-08 | Forme posologique orale a liberation regulee amelioree |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2796884A Division CA2796884A1 (fr) | 2001-02-08 | 2002-02-08 | Forme posologique orale a liberation regulee amelioree |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2685214A1 CA2685214A1 (fr) | 2002-08-15 |
| CA2685214C true CA2685214C (fr) | 2013-01-22 |
Family
ID=26952450
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2796884A Abandoned CA2796884A1 (fr) | 2001-02-08 | 2002-02-08 | Forme posologique orale a liberation regulee amelioree |
| CA2433915A Expired - Fee Related CA2433915C (fr) | 2001-02-08 | 2002-02-08 | Forme posologique orale a liberation regulee amelioree |
| CA2685214A Expired - Fee Related CA2685214C (fr) | 2001-02-08 | 2002-02-08 | Forme posologique orale a liberation regulee amelioree |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2796884A Abandoned CA2796884A1 (fr) | 2001-02-08 | 2002-02-08 | Forme posologique orale a liberation regulee amelioree |
| CA2433915A Expired - Fee Related CA2433915C (fr) | 2001-02-08 | 2002-02-08 | Forme posologique orale a liberation regulee amelioree |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP1357898A4 (fr) |
| CA (3) | CA2796884A1 (fr) |
| WO (1) | WO2002062299A2 (fr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8545880B2 (en) | 1999-02-26 | 2013-10-01 | Andrx Pharmaceuticals, Llc | Controlled release oral dosage form |
| CN1819821B (zh) | 2003-08-08 | 2010-10-13 | 拜奥维尔实验室国际股份有限公司 | 盐酸安非他酮的改良释放片剂 |
| CN101146521A (zh) * | 2005-03-14 | 2008-03-19 | 太阳医药高级研究有限公司 | 提供包含纤维素和甲基丙烯酸衍生物包衣的口服药物输送系统 |
| BRPI0719021A2 (pt) | 2006-11-21 | 2013-12-17 | Mcneil-Ppc, Inc. | Suspensões analgésicas de liberação modificada. |
| US9833510B2 (en) | 2007-06-12 | 2017-12-05 | Johnson & Johnson Consumer Inc. | Modified release solid or semi-solid dosage forms |
| KR20140069381A (ko) | 2009-06-02 | 2014-06-10 | 다우 글로벌 테크놀로지스 엘엘씨 | 서방출 투여형 |
| CN110200947A (zh) * | 2019-06-27 | 2019-09-06 | 深圳市泛谷药业股份有限公司 | 一种安非他酮肠溶缓释微丸胶囊及其制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0653935B1 (fr) * | 1992-08-05 | 2002-05-08 | F.H. FAULDING & CO. LIMITED | Composition pharmaceutique sous forme de granules |
| GB9217295D0 (en) * | 1992-08-14 | 1992-09-30 | Wellcome Found | Controlled released tablets |
| US6270805B1 (en) * | 1998-11-06 | 2001-08-07 | Andrx Pharmaceuticals, Inc. | Two pellet controlled release formulation for water soluble drugs which contains an alkaline metal stearate |
| US6210716B1 (en) * | 1999-02-26 | 2001-04-03 | Andrx Pharmaceuticals, Inc. | Controlled release bupropion formulation |
-
2002
- 2002-02-08 EP EP02723104A patent/EP1357898A4/fr not_active Withdrawn
- 2002-02-08 CA CA2796884A patent/CA2796884A1/fr not_active Abandoned
- 2002-02-08 CA CA2433915A patent/CA2433915C/fr not_active Expired - Fee Related
- 2002-02-08 WO PCT/US2002/003523 patent/WO2002062299A2/fr not_active Ceased
- 2002-02-08 CA CA2685214A patent/CA2685214C/fr not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2685214A1 (fr) | 2002-08-15 |
| WO2002062299A3 (fr) | 2003-04-24 |
| CA2433915C (fr) | 2010-04-20 |
| WO2002062299A2 (fr) | 2002-08-15 |
| CA2433915A1 (fr) | 2002-08-15 |
| EP1357898A4 (fr) | 2005-07-13 |
| EP1357898A2 (fr) | 2003-11-05 |
| CA2796884A1 (fr) | 2002-08-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20210831 |
|
| MKLA | Lapsed |
Effective date: 20200210 |