CA2718802C - Acides nucleiques recombinants comportant des regions d'ad6 - Google Patents

Acides nucleiques recombinants comportant des regions d'ad6 Download PDF

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Publication number
CA2718802C
CA2718802C CA2718802A CA2718802A CA2718802C CA 2718802 C CA2718802 C CA 2718802C CA 2718802 A CA2718802 A CA 2718802A CA 2718802 A CA2718802 A CA 2718802A CA 2718802 C CA2718802 C CA 2718802C
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CA
Canada
Prior art keywords
region
base pair
seq
hcv
adenovirus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA2718802A
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English (en)
Other versions
CA2718802A1 (fr
Inventor
David C. Kaslow
Andrew J. Bett
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Merck Sharp and Dohme LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp and Dohme LLC filed Critical Merck Sharp and Dohme LLC
Priority claimed from CA2461380A external-priority patent/CA2461380C/fr
Publication of CA2718802A1 publication Critical patent/CA2718802A1/fr
Application granted granted Critical
Publication of CA2718802C publication Critical patent/CA2718802C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention a trait à des vecteurs Ad6 et un acide nucléique codant un polypeptide Met-NS3-NS4A-NS4B-NS5A-NS5B contenant une zone ARN polymérase ARN dépendante NS5B inactive. L'acide nucléique est particulièrement utile comme composant d'un adénovecteur ou vaccin plasmidique d'ADN fournissant une vaste gamme d'antigènes pour produire, contre le VHC, une réponse immunitaire à médiation cellulaire spécifique au VHC.
CA2718802A 2001-10-11 2002-10-10 Acides nucleiques recombinants comportant des regions d'ad6 Expired - Lifetime CA2718802C (fr)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US32865501P 2001-10-11 2001-10-11
US60/328,655 2001-10-11
US36377402P 2002-03-13 2002-03-13
US60/363,774 2002-03-13
CA2461380A CA2461380C (fr) 2001-10-11 2002-10-10 Vaccin contre le virus de l'hepatite c
PCT/US2002/032512 WO2003031588A2 (fr) 2001-10-11 2002-10-10 Vaccin contre le virus de l'hepatite c

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA2461380A Division CA2461380C (fr) 2001-10-11 2002-10-10 Vaccin contre le virus de l'hepatite c

Publications (2)

Publication Number Publication Date
CA2718802A1 CA2718802A1 (fr) 2003-04-17
CA2718802C true CA2718802C (fr) 2013-11-26

Family

ID=42828996

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2718802A Expired - Lifetime CA2718802C (fr) 2001-10-11 2002-10-10 Acides nucleiques recombinants comportant des regions d'ad6

Country Status (2)

Country Link
CA (1) CA2718802C (fr)
SI (1) SI1436397T1 (fr)

Also Published As

Publication number Publication date
CA2718802A1 (fr) 2003-04-17
SI1436397T1 (sl) 2010-09-30

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Legal Events

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EEER Examination request
MKEX Expiry

Effective date: 20221011

MKEX Expiry

Effective date: 20221011