CA2747154C - Immunocytokines pour therapie tumorale avec agents chimiotherapiques - Google Patents
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- CA2747154C CA2747154C CA2747154A CA2747154A CA2747154C CA 2747154 C CA2747154 C CA 2747154C CA 2747154 A CA2747154 A CA 2747154A CA 2747154 A CA2747154 A CA 2747154A CA 2747154 C CA2747154 C CA 2747154C
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- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
- A61K47/6865—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from skin, nerves or brain cancer cell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13948408P | 2008-12-19 | 2008-12-19 | |
| US61/139,484 | 2008-12-19 | ||
| PCT/EP2009/008920 WO2010078916A1 (fr) | 2008-12-19 | 2009-12-14 | Immunocytokines pour thérapie tumorale avec agents chimiothérapiques |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2747154A1 CA2747154A1 (fr) | 2010-07-15 |
| CA2747154C true CA2747154C (fr) | 2015-11-10 |
Family
ID=42154562
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2747154A Expired - Fee Related CA2747154C (fr) | 2008-12-19 | 2009-12-14 | Immunocytokines pour therapie tumorale avec agents chimiotherapiques |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US8580267B2 (fr) |
| EP (1) | EP2373343B1 (fr) |
| CA (1) | CA2747154C (fr) |
| WO (1) | WO2010078916A1 (fr) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120107270A1 (en) * | 2009-06-30 | 2012-05-03 | Manuela Kaspar | Immunocytokines In Combination With Anti-ErbB Antibodies For The Treatment Of Cancer |
| WO2012041451A1 (fr) | 2010-09-29 | 2012-04-05 | Philogen S.P.A. | Liant à base de thiazolidine pour la conjugaison de médicaments à des anticorps |
| EP2718457A4 (fr) * | 2011-06-06 | 2014-12-24 | Immungene Inc | Molécules de fusion génétiquement modifiées ligand élément tnfsf-anticorps |
| US9549981B2 (en) * | 2011-07-19 | 2017-01-24 | Philogen S.P.A. | Sequential antibody therapy |
| WO2014023329A1 (fr) * | 2012-08-06 | 2014-02-13 | Life And Brain Gmbh | Niclosamide et ses dérivés destinés à être utilisés dans le traitement de tumeurs solides |
| WO2014078522A1 (fr) | 2012-11-14 | 2014-05-22 | Ohio State Innovation Foundation | Matières et procédés utiles pour le traitement du glioblastome |
| EP3047024B1 (fr) | 2013-09-20 | 2019-04-24 | University Of Virginia Patent Foundation | Compositions et méthodes destinées à traiter les maladies et les troubles auto-immuns et inflammatoires |
| WO2015114166A2 (fr) * | 2014-02-03 | 2015-08-06 | Philochem Ag | Conjugués médicamenteux ciblés |
| US10906963B2 (en) | 2016-04-15 | 2021-02-02 | Philogen S.P.A | Non-glycosylated anti-tenascin antibody |
| GB201621806D0 (en) | 2016-12-21 | 2017-02-01 | Philogen Spa | Immunocytokines with progressive activation mechanism |
| WO2019014600A1 (fr) * | 2017-07-13 | 2019-01-17 | Plex Pharmaceuticals, Inc. | Traitement d'association pour le traitement du cancer |
| WO2019139987A1 (fr) | 2018-01-09 | 2019-07-18 | Elstar Therapeutics, Inc. | Constructions de liaison à la calréticuline et lymphocytes t modifiés pour le traitement de maladies |
| TWI844524B (zh) * | 2018-02-09 | 2024-06-11 | 義大利商費洛根公司 | 靶向edb之il-12組合物 |
| US12152073B2 (en) | 2018-03-14 | 2024-11-26 | Marengo Therapeutics, Inc. | Multifunctional molecules that bind to calreticulin and uses thereof |
| WO2020010250A2 (fr) | 2018-07-03 | 2020-01-09 | Elstar Therapeutics, Inc. | Molécules d'anticorps anti-tcr et leurs utilisations |
| AU2020226893B2 (en) | 2019-02-21 | 2025-02-27 | Marengo Therapeutics, Inc. | Multifunctional molecules that bind to T cell related cancer cells and uses thereof |
| GB2597851B (en) | 2019-02-21 | 2024-05-29 | Marengo Therapeutics Inc | Antibody molecules that bind to NKP30 and uses thereof |
| AU2020416273A1 (en) | 2020-01-03 | 2022-07-28 | Marengo Therapeutics, Inc. | Anti-TCR antibody molecules and uses thereof |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| JPS61134325A (ja) | 1984-12-04 | 1986-06-21 | Teijin Ltd | ハイブリツド抗体遺伝子の発現方法 |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| JP3720353B2 (ja) | 1992-12-04 | 2005-11-24 | メディカル リサーチ カウンシル | 多価および多重特異性の結合タンパク質、それらの製造および使用 |
| PT1257297E (pt) | 2000-02-24 | 2006-12-29 | Philogen Spa | Composições e método para tratamento da angiogénese em lesões patológicas |
| NZ527173A (en) * | 2000-12-29 | 2006-03-31 | Savient Pharmaceuticals Inc | Specific human antibodies for selective cancer therapy |
| GB0209896D0 (en) | 2002-04-30 | 2002-06-05 | Molmed Spa | Conjugate |
| KR20050059001A (ko) * | 2002-07-01 | 2005-06-17 | 사비언트 파마슈티컬즈 인코퍼레이티드 | 치료적 처리를 위한 조성물 및 방법 |
| US20060024722A1 (en) | 2004-07-30 | 2006-02-02 | Mark Fischer-Colbrie | Samples for detection of oncofetal fibronectin and uses thereof |
| PL1817345T3 (pl) | 2004-11-09 | 2009-10-30 | Philogen Spa | Przeciwciała przeciwko tenascynie-C |
| US20090298195A1 (en) | 2005-01-05 | 2009-12-03 | F-Star Biotechnologische Forschungs-Und Entwicklun Gseges M.B.H. | Synthetic immunoglobulin domains with binding properties engineered in regions of the molecule different from the complementarity determining regions |
| KR101281208B1 (ko) | 2005-05-11 | 2013-07-26 | 필로겐 에스.피.에이. | 피브로넥틴 ｅｄ-ｂ에 대한 항체 ｌ１９ 및 인터루킨１２의 융합 단백질 |
| KR20090008467A (ko) * | 2006-05-08 | 2009-01-21 | 필로겐 에스.피.에이. | 치료용의 항체표적 사이토카인 |
| US9209965B2 (en) | 2014-01-14 | 2015-12-08 | Microsemi Semiconductor Ulc | Network interface with clock recovery module on line card |
-
2009
- 2009-12-14 US US13/139,655 patent/US8580267B2/en not_active Expired - Fee Related
- 2009-12-14 EP EP09795702.1A patent/EP2373343B1/fr not_active Not-in-force
- 2009-12-14 CA CA2747154A patent/CA2747154C/fr not_active Expired - Fee Related
- 2009-12-14 WO PCT/EP2009/008920 patent/WO2010078916A1/fr not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US20110250170A1 (en) | 2011-10-13 |
| US8580267B2 (en) | 2013-11-12 |
| EP2373343B1 (fr) | 2015-02-11 |
| EP2373343A1 (fr) | 2011-10-12 |
| WO2010078916A4 (fr) | 2010-09-10 |
| WO2010078916A1 (fr) | 2010-07-15 |
| CA2747154A1 (fr) | 2010-07-15 |
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| EEER | Examination request |
Effective date: 20141208 |
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| MKLA | Lapsed |
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