CA2767614C - Schemas posologiques de l'acide fusidique pour le traitement d'infections bacteriennes - Google Patents

Schemas posologiques de l'acide fusidique pour le traitement d'infections bacteriennes Download PDF

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Publication number
CA2767614C
CA2767614C CA2767614A CA2767614A CA2767614C CA 2767614 C CA2767614 C CA 2767614C CA 2767614 A CA2767614 A CA 2767614A CA 2767614 A CA2767614 A CA 2767614A CA 2767614 C CA2767614 C CA 2767614C
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dose
administered
hours
administration
formulated
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CA2767614A1 (fr
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Ronald Jones
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Arrevus Inc
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Cempra Pharmaceuticals Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention concerne de nouveaux schémas posologiques pour le traitement et la prévention d?infections bactériennes à l?aide d?acide fusidique. Il a été découvert que l?utilisation d?une dose de charge élevée d?acide fusidique, suivie de doses d?entretien modérées du médicament, prévient le développement de souches de bactéries résistant au médicament, augmente le spectre efficace du médicament, et évite les nausées et vomissements associés à un traitement prolongé avec des quantités élevées du médicament.
CA2767614A 2009-07-13 2009-07-13 Schemas posologiques de l'acide fusidique pour le traitement d'infections bacteriennes Active CA2767614C (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2009/050353 WO2011008193A1 (fr) 2009-07-13 2009-07-13 Schémas posologiques de l’acide fusidique pour le traitement d’infections bactériennes

Publications (2)

Publication Number Publication Date
CA2767614A1 CA2767614A1 (fr) 2011-01-20
CA2767614C true CA2767614C (fr) 2019-01-15

Family

ID=43449613

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2767614A Active CA2767614C (fr) 2009-07-13 2009-07-13 Schemas posologiques de l'acide fusidique pour le traitement d'infections bacteriennes

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CA (1) CA2767614C (fr)
WO (1) WO2011008193A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1638549A4 (fr) 2003-03-10 2011-06-15 Optimer Pharmaceuticals Inc Nouveaux agents antibacteriens
CA2703475A1 (fr) 2007-10-25 2009-04-30 Cempra Pharmaceuticals, Inc. Procede pour la preparation d'agents antibacteriens macrolides
US8796232B2 (en) 2008-10-24 2014-08-05 Cempra Pharmaceuticals, Inc. Methods for treating resistant diseases using triazole containing macrolides
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
JP5914335B2 (ja) 2009-09-10 2016-05-11 センプラ ファーマシューティカルズ，インコーポレイテッド マラリア、結核、及びｍａｃ病の治療方法
WO2011146829A1 (fr) 2010-05-20 2011-11-24 Cempra Pharmaceuticals, Inc. Procédés de préparation de macrolides et de kétolides et d'intermédiaires de ceux-ci
JP6042334B2 (ja) 2010-09-10 2016-12-14 センプラ ファーマシューティカルズ，インコーポレイテッド 疾患治療のための水素結合形成フルオロケトライド
CN104470527B (zh) 2012-03-27 2019-05-28 森普拉制药公司 用于施用大环内酯抗生素的肠胃外制剂
RU2015138796A (ru) 2013-03-14 2017-04-19 Семпра Фармасьютикалс, Инк. Способы и составы для лечения респираторных заболеваний
WO2014145210A1 (fr) 2013-03-15 2014-09-18 Cempra Pharmaceuticals, Inc. Procédés convergents de préparation d'agents antibactériens macrolides
US9345717B2 (en) 2013-09-25 2016-05-24 Zavante Therapeutics, Inc. Method for improving drug treatments in mammals
CN116650399B (zh) * 2023-04-13 2025-09-05 福元药业有限公司 一种夫西地酸乳膏及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1115417T3 (da) * 1998-09-25 2006-07-31 Cubist Pharm Inc Anvendelse af daptomycin
US6991807B2 (en) * 2000-02-24 2006-01-31 Advancis Pharmaceutical, Corp. Antibiotic composition

Also Published As

Publication number Publication date
CA2767614A1 (fr) 2011-01-20
WO2011008193A1 (fr) 2011-01-20

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