CA2841499C - Compositions et methodes pour prevenir les infections sternales de blessures - Google Patents

Compositions et methodes pour prevenir les infections sternales de blessures Download PDF

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Publication number
CA2841499C
CA2841499C CA2841499A CA2841499A CA2841499C CA 2841499 C CA2841499 C CA 2841499C CA 2841499 A CA2841499 A CA 2841499A CA 2841499 A CA2841499 A CA 2841499A CA 2841499 C CA2841499 C CA 2841499C
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CA
Canada
Prior art keywords
tyrosine
polymer
acid
polymers
poly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2841499A
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English (en)
Other versions
CA2841499A1 (fr
Inventor
Raman Bahulekar
Arikha Moses
Fatima Buevich
Satish Pulapura
William C. McJames
Original Assignee
Medtronic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medtronic Inc filed Critical Medtronic Inc
Publication of CA2841499A1 publication Critical patent/CA2841499A1/fr
Application granted granted Critical
Publication of CA2841499C publication Critical patent/CA2841499C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/0066—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0019—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/009—Materials resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Linvention porte généralement sur des compositions et des méthodes servant à prévenir les infections de blessures sternales comme la médiastinite. Dans certaines réalisations, linvention fournit une composition antimicrobienne comprenant au moins un polymère biorésorbable, comme un polyestéramide dérivé de tyrosine, et au moins un agent antimicrobien, dans lequel la composition est adaptée pour être appliquée de manière topique à une perforation sophagienne chez un sujet ou sur un site dincision de sternotomie médiane chez un sujet, et dans laquelle au moins un agent antimicrobien est présent dans une quantité efficace pour empêcher le développement de la médiastinite chez le sujet.
CA2841499A 2009-06-01 2010-06-01 Compositions et methodes pour prevenir les infections sternales de blessures Active CA2841499C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US46074309P 2009-06-01 2009-06-01
US61/460,743 2009-06-01
CA2764134A CA2764134C (fr) 2009-06-01 2010-06-01 Compositions et methodes pour prevenir les infections sternales de blessures

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA2764134A Division CA2764134C (fr) 2009-06-01 2010-06-01 Compositions et methodes pour prevenir les infections sternales de blessures

Publications (2)

Publication Number Publication Date
CA2841499A1 CA2841499A1 (fr) 2010-12-09
CA2841499C true CA2841499C (fr) 2016-07-26

Family

ID=46578667

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2841499A Active CA2841499C (fr) 2009-06-01 2010-06-01 Compositions et methodes pour prevenir les infections sternales de blessures
CA2764134A Active CA2764134C (fr) 2009-06-01 2010-06-01 Compositions et methodes pour prevenir les infections sternales de blessures

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2764134A Active CA2764134C (fr) 2009-06-01 2010-06-01 Compositions et methodes pour prevenir les infections sternales de blessures

Country Status (2)

Country Link
AU (1) AU2010256750B2 (fr)
CA (2) CA2841499C (fr)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8795242B2 (en) * 1994-05-13 2014-08-05 Kensey Nash Corporation Resorbable polymeric device for localized drug delivery
MX2008010126A (es) * 2006-02-08 2010-02-22 Tyrx Pharma Inc Protesis de malla temporalmente rigidizadas.
US8591531B2 (en) * 2006-02-08 2013-11-26 Tyrx, Inc. Mesh pouches for implantable medical devices
CA2664682C (fr) * 2006-10-17 2012-12-04 Reva Medical, Inc. Monomeres et polymeres n-substitues
WO2008157777A1 (fr) * 2007-06-21 2008-12-24 Tyrx Pharma, Inc. Chaînes latérales d'ester de phényle permettant d'accroître la capacité de résorption des polymères

Also Published As

Publication number Publication date
CA2764134A1 (fr) 2010-12-09
AU2010256750B2 (en) 2015-03-05
CA2841499A1 (fr) 2010-12-09
CA2764134C (fr) 2014-04-15
AU2010256750A1 (en) 2012-01-19

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