CA2857043C - Composition a base de silicone pour le traitement de la peau - Google Patents

Composition a base de silicone pour le traitement de la peau Download PDF

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Publication number
CA2857043C
CA2857043C CA2857043A CA2857043A CA2857043C CA 2857043 C CA2857043 C CA 2857043C CA 2857043 A CA2857043 A CA 2857043A CA 2857043 A CA2857043 A CA 2857043A CA 2857043 C CA2857043 C CA 2857043C
Authority
CA
Canada
Prior art keywords
silicone
based gel
approximately
active ingredient
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2857043A
Other languages
English (en)
Other versions
CA2857043A1 (fr
Inventor
Jay Richard Ii Ray
Charles D. Hodge
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CMPD Licensing LLC
Original Assignee
CMPD Licensing LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CMPD Licensing LLC filed Critical CMPD Licensing LLC
Publication of CA2857043A1 publication Critical patent/CA2857043A1/fr
Application granted granted Critical
Publication of CA2857043C publication Critical patent/CA2857043C/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/695Silicon compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA2857043A 2011-12-27 2012-12-27 Composition a base de silicone pour le traitement de la peau Expired - Fee Related CA2857043C (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201113337614A 2011-12-27 2011-12-27
US13/337,614 2011-12-27
US13/564,467 US9592241B2 (en) 2011-12-27 2012-08-01 Silicone-based composition for skin treatment
US13/564,467 2012-08-01
PCT/US2012/071818 WO2013101929A1 (fr) 2011-12-27 2012-12-27 Composition à base de silicone pour le traitement de la peau

Publications (2)

Publication Number Publication Date
CA2857043A1 CA2857043A1 (fr) 2013-07-04
CA2857043C true CA2857043C (fr) 2016-01-05

Family

ID=48655158

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2857043A Expired - Fee Related CA2857043C (fr) 2011-12-27 2012-12-27 Composition a base de silicone pour le traitement de la peau

Country Status (5)

Country Link
US (4) US9592241B2 (fr)
EP (1) EP2797593A4 (fr)
AU (1) AU2012362398A1 (fr)
CA (1) CA2857043C (fr)
WO (1) WO2013101929A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9592241B2 (en) 2011-12-27 2017-03-14 Cmpd Licensing, Llc Silicone-based composition for skin treatment
WO2015081007A1 (fr) * 2013-11-26 2015-06-04 Humco Holding Group, Inc. Compositions de gel de silicone (silogel) transdermiques et procédés de préparation
US9511034B1 (en) 2013-12-09 2016-12-06 Bio-Silicote, Inc. Method for applying a skin treatment
US11446236B2 (en) 2015-08-05 2022-09-20 Cmpd Licensing, Llc Topical antimicrobial compositions and methods of formulating the same
US11793783B2 (en) 2015-08-05 2023-10-24 Cmpd Licensing, Llc Compositions and methods for treating an infection
US11684567B2 (en) 2015-08-05 2023-06-27 Cmpd Licensing, Llc Compositions and methods for treating an infection
CN108403623A (zh) * 2018-05-29 2018-08-17 南京华开生物科技有限公司 硅酮疤痕凝胶
WO2020178005A1 (fr) * 2019-03-01 2020-09-10 Wasserman Medic AB Nouvelles compositions et leur utilisation
WO2022119428A1 (fr) * 2020-12-04 2022-06-09 Laboratorios Silanes S.A. De C.V. Combinaison pharmaceutique d'un corticostéroïde et d'un antihistaminique pour le traitement et la régulation du composant inflammatoire de processus allergiques

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6472165B1 (en) * 1999-08-03 2002-10-29 Arzneimittelwerk Dresden Gmbh Modulatory binding site in potassium channels for screening and finding new active ingredients
GB0007140D0 (en) 1999-09-27 2000-05-17 Dow Corning Sa Scar treatment composition
US10179159B2 (en) * 1999-10-22 2019-01-15 Scott Wepfer Topical anesthetic formulation
US6337076B1 (en) 1999-11-17 2002-01-08 Sg Licensing Corporation Method and composition for the treatment of scars
US6673363B2 (en) * 1999-12-16 2004-01-06 Dermatrends, Inc. Transdermal and topical administration of local anesthetic agents using basic enhancers
US20050014729A1 (en) 2003-07-16 2005-01-20 Pharmacia Corporation Method for the treatment or prevention of dermatological disorders with a cyclooxygenase-2 inhibitor alone and in combination with a dermatological treatment agent and compositions therewith
US20050267258A1 (en) * 2004-05-26 2005-12-01 Rajaraman Suresh K Evaporable silicone carriers for cosmetics, cleaning and care product compositions
US20060013866A1 (en) * 2004-07-16 2006-01-19 Carter Stephen G Transdermal drug delivery formulations with optimal amounts of vasodilators therein
US8557287B2 (en) 2004-08-06 2013-10-15 Jeff S. Schleuning Silicone gel composition and dispenser therefor
US20080153786A1 (en) * 2006-05-22 2008-06-26 Galderma S.A. Controlled release of drugs into/through the skin
US20110046532A1 (en) 2006-01-30 2011-02-24 Sanjeev Kaila composition including a silicone-based polymer and a method of treating skin disorders using the composition
CA2644311C (fr) 2006-03-01 2012-07-10 Tristrata, Inc. Compositions et procedes pour le traitement topique de troubles dermatologiques repondants au goudron
TW200932292A (en) 2007-09-30 2009-08-01 Valeant Pharmaceuticals Int Silicone gel-based compositions for wound healing and scar reduction
WO2010036937A1 (fr) 2008-09-27 2010-04-01 Taraxos Inc. Formulations topiques pour le traitement d’une neuropathie
US20100322875A1 (en) 2009-06-18 2010-12-23 Advanced Bio-Technologies, Inc. Silicone scar treatment preparation
WO2011022652A1 (fr) 2009-08-21 2011-02-24 Novan, Inc. Gels topiques
US9592241B2 (en) 2011-12-27 2017-03-14 Cmpd Licensing, Llc Silicone-based composition for skin treatment

Also Published As

Publication number Publication date
US20170182167A1 (en) 2017-06-29
EP2797593A4 (fr) 2014-12-17
US9271989B2 (en) 2016-03-01
CA2857043A1 (fr) 2013-07-04
US10064949B2 (en) 2018-09-04
US20190060464A1 (en) 2019-02-28
US9592241B2 (en) 2017-03-14
EP2797593A1 (fr) 2014-11-05
US10660962B2 (en) 2020-05-26
US20150182538A1 (en) 2015-07-02
WO2013101929A1 (fr) 2013-07-04
AU2012362398A1 (en) 2014-08-21
US20130165420A1 (en) 2013-06-27

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20140526

MKLA Lapsed

Effective date: 20171227