CA2874761A1 - Compositions et procedes pour une detection et un traitement non invasifs de cellules hypoxiques in vivo - Google Patents

Compositions et procedes pour une detection et un traitement non invasifs de cellules hypoxiques in vivo Download PDF

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Publication number
CA2874761A1
CA2874761A1 CA2874761A CA2874761A CA2874761A1 CA 2874761 A1 CA2874761 A1 CA 2874761A1 CA 2874761 A CA2874761 A CA 2874761A CA 2874761 A CA2874761 A CA 2874761A CA 2874761 A1 CA2874761 A1 CA 2874761A1
Authority
CA
Canada
Prior art keywords
hypoxia
compound
hypoxic
microbubble
targeting agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2874761A
Other languages
English (en)
Inventor
Nathan A. KOONCE
Robert Griffin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BioVentures LLC
Original Assignee
University of Arkansas at Little Rock
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Arkansas at Little Rock filed Critical University of Arkansas at Little Rock
Publication of CA2874761A1 publication Critical patent/CA2874761A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasonic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasonic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0028—Disruption, e.g. by heat or ultrasounds, sonophysical or sonochemical activation, e.g. thermosensitive or heat-sensitive liposomes, disruption of calculi with a medicinal preparation and ultrasounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasonic imaging preparations
    • A61K49/221—Echographic preparations; Ultrasonic imaging preparations characterised by the targeting agent or modifying agent linked to the acoustically-active agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1203—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules in a form not provided for by groups A61K51/1206 - A61K51/1296, e.g. cells, cell fragments, viruses, virus capsides, ghosts, red blood cells, viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N7/02—Localised ultrasound hyperthermia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0039—Ultrasound therapy using microbubbles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/70—Mechanisms involved in disease identification
    • G01N2800/7038—Hypoxia

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Acoustics & Sound (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Dispersion Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2874761A 2012-06-14 2013-06-14 Compositions et procedes pour une detection et un traitement non invasifs de cellules hypoxiques in vivo Abandoned CA2874761A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261659832P 2012-06-14 2012-06-14
US61/659,832 2012-06-14
PCT/US2013/045867 WO2013188755A2 (fr) 2012-06-14 2013-06-14 Compositions et procédés pour une détection et un traitement non invasifs de cellules hypoxiques in vivo

Publications (1)

Publication Number Publication Date
CA2874761A1 true CA2874761A1 (fr) 2013-12-19

Family

ID=49758909

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2874761A Abandoned CA2874761A1 (fr) 2012-06-14 2013-06-14 Compositions et procedes pour une detection et un traitement non invasifs de cellules hypoxiques in vivo

Country Status (6)

Country Link
US (1) US20150141875A1 (fr)
EP (1) EP2877212A4 (fr)
AU (1) AU2013274093A1 (fr)
CA (1) CA2874761A1 (fr)
HK (1) HK1210024A1 (fr)
WO (1) WO2013188755A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210353249A1 (en) * 2020-05-12 2021-11-18 Acoustiic Inc. Detection and treatment of tumors using ultrasound

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6331289B1 (en) * 1996-10-28 2001-12-18 Nycomed Imaging As Targeted diagnostic/therapeutic agents having more than one different vectors
US20070036722A1 (en) * 1996-10-28 2007-02-15 Pal Rongved Separation processes
US7067111B1 (en) * 1999-10-25 2006-06-27 Board Of Regents, University Of Texas System Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging
DE10119522A1 (de) * 2001-04-20 2002-12-05 Innovacell Biotechnologie Gmbh Herstellung und Anwendung einer Suspensionszusammensetzung mit einem Ultraschall-Kontrastmittel
ATE466596T1 (de) * 2004-01-20 2010-05-15 Sunnybrook & Womens College Hochfrequenz-ultraschall-darstellung mit kontrastmitteln
US20090060842A1 (en) * 2007-09-03 2009-03-05 Jens Fehre Method for diagnosis and treatment of prostatitis
EP2200652B1 (fr) * 2007-09-27 2018-03-21 Children's Medical Center Corporation Microbulles et procédés de livraison d'oxygène
EP2130553A1 (fr) * 2008-06-05 2009-12-09 Nanobiotix Nanoparticules inorganiques de haute densité pour détruire des cellules in-vivo

Also Published As

Publication number Publication date
US20150141875A1 (en) 2015-05-21
AU2013274093A1 (en) 2014-12-18
HK1210024A1 (en) 2016-04-15
EP2877212A4 (fr) 2016-04-27
WO2013188755A3 (fr) 2014-02-06
EP2877212A2 (fr) 2015-06-03
WO2013188755A2 (fr) 2013-12-19

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20190614