CA2892012A1 - Mutations dans des solanacees modulant l'architecture de la pousse et ameliorant les phenotypes associes au rendement - Google Patents

Mutations dans des solanacees modulant l'architecture de la pousse et ameliorant les phenotypes associes au rendement Download PDF

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Publication number
CA2892012A1
CA2892012A1 CA2892012A CA2892012A CA2892012A1 CA 2892012 A1 CA2892012 A1 CA 2892012A1 CA 2892012 A CA2892012 A CA 2892012A CA 2892012 A CA2892012 A CA 2892012A CA 2892012 A1 CA2892012 A1 CA 2892012A1
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Prior art keywords
mutant
altered
genetically
gene
seq
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Pending
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CA2892012A
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English (en)
Inventor
Zachary Lippman
Soon-Ju PARK
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Cold Spring Harbor Laboratory
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Cold Spring Harbor Laboratory
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Priority claimed from US13/799,831 external-priority patent/US9732352B2/en
Application filed by Cold Spring Harbor Laboratory filed Critical Cold Spring Harbor Laboratory
Publication of CA2892012A1 publication Critical patent/CA2892012A1/fr
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8262Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield involving plant development
    • C12N15/827Flower development or morphology, e.g. flowering promoting factor [FPF]
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01HNEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H5/00Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
    • A01H5/08Fruits
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Botany (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Environmental Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne des solanacées génétiquement modifiées, des compositions associées aux solanacées,et des procédés d'élaboration de ces solanacées.
CA2892012A 2012-11-20 2013-11-19 Mutations dans des solanacees modulant l'architecture de la pousse et ameliorant les phenotypes associes au rendement Pending CA2892012A1 (fr)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201261728654P 2012-11-20 2012-11-20
US61/728,654 2012-11-20
US13/799,831 2013-03-13
US13/799,831 US9732352B2 (en) 2012-11-20 2013-03-13 Mutations in Solanaceae plants that modulate shoot architecture and enhance yield-related phenotypes
US201361869052P 2013-08-22 2013-08-22
US61/869,052 2013-08-22
PCT/US2013/070825 WO2014081730A1 (fr) 2012-11-20 2013-11-19 Mutations dans des solanacées modulant l'architecture de la pousse et améliorant les phénotypes associés au rendement

Publications (1)

Publication Number Publication Date
CA2892012A1 true CA2892012A1 (fr) 2014-05-30

Family

ID=50776499

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2892012A Pending CA2892012A1 (fr) 2012-11-20 2013-11-19 Mutations dans des solanacees modulant l'architecture de la pousse et ameliorant les phenotypes associes au rendement

Country Status (3)

Country Link
EP (1) EP2922960A4 (fr)
CA (1) CA2892012A1 (fr)
WO (1) WO2014081730A1 (fr)

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US10323236B2 (en) 2011-07-22 2019-06-18 President And Fellows Of Harvard College Evaluation and improvement of nuclease cleavage specificity
US9732352B2 (en) 2012-11-20 2017-08-15 Cold Spring Harbor Laboratory Mutations in Solanaceae plants that modulate shoot architecture and enhance yield-related phenotypes
US9163284B2 (en) 2013-08-09 2015-10-20 President And Fellows Of Harvard College Methods for identifying a target site of a Cas9 nuclease
US9228207B2 (en) 2013-09-06 2016-01-05 President And Fellows Of Harvard College Switchable gRNAs comprising aptamers
US9526784B2 (en) 2013-09-06 2016-12-27 President And Fellows Of Harvard College Delivery system for functional nucleases
US9322037B2 (en) 2013-09-06 2016-04-26 President And Fellows Of Harvard College Cas9-FokI fusion proteins and uses thereof
CN106459995B (zh) 2013-11-07 2020-02-21 爱迪塔斯医药有限公司 使用统治型gRNA的CRISPR相关方法和组合物
US20150165054A1 (en) 2013-12-12 2015-06-18 President And Fellows Of Harvard College Methods for correcting caspase-9 point mutations
US10077453B2 (en) 2014-07-30 2018-09-18 President And Fellows Of Harvard College CAS9 proteins including ligand-dependent inteins
IL310721B2 (en) 2015-10-23 2025-11-01 Harvard College Nucleobase editors and uses thereof
EP3443104A4 (fr) * 2016-04-11 2019-11-27 Cold Spring Harbor Laboratory Jeu d'outils de la voie des substances florigènes
CN110214183A (zh) 2016-08-03 2019-09-06 哈佛大学的校长及成员们 腺苷核碱基编辑器及其用途
WO2018031683A1 (fr) 2016-08-09 2018-02-15 President And Fellows Of Harvard College Protéines de fusion cas9-recombinase programmables et utilisations associées
US11542509B2 (en) 2016-08-24 2023-01-03 President And Fellows Of Harvard College Incorporation of unnatural amino acids into proteins using base editing
KR102622411B1 (ko) 2016-10-14 2024-01-10 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 핵염기 에디터의 aav 전달
KR102606956B1 (ko) * 2016-12-20 2023-11-29 필립모리스 프로덕츠 에스.에이. 개화까지의 시간이 단축된 식물
WO2018119359A1 (fr) 2016-12-23 2018-06-28 President And Fellows Of Harvard College Édition du gène récepteur ccr5 pour protéger contre l'infection par le vih
EP3592853A1 (fr) 2017-03-09 2020-01-15 President and Fellows of Harvard College Suppression de la douleur par édition de gène
US12390514B2 (en) 2017-03-09 2025-08-19 President And Fellows Of Harvard College Cancer vaccine
US11542496B2 (en) 2017-03-10 2023-01-03 President And Fellows Of Harvard College Cytosine to guanine base editor
KR20240116572A (ko) 2017-03-23 2024-07-29 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 핵산 프로그램가능한 dna 결합 단백질을 포함하는 핵염기 편집제
US11560566B2 (en) 2017-05-12 2023-01-24 President And Fellows Of Harvard College Aptazyme-embedded guide RNAs for use with CRISPR-Cas9 in genome editing and transcriptional activation
US20220002740A2 (en) * 2017-05-17 2022-01-06 Cold Spring Harbor Laboratory Mutations in mads-box genes and uses thereof
CN111801345A (zh) 2017-07-28 2020-10-20 哈佛大学的校长及成员们 使用噬菌体辅助连续进化(pace)的进化碱基编辑器的方法和组合物
EP3676376B1 (fr) 2017-08-30 2025-01-15 President and Fellows of Harvard College Éditeurs de bases à haut rendement comprenant une gam
KR20250107288A (ko) 2017-10-16 2025-07-11 더 브로드 인스티튜트, 인코퍼레이티드 아데노신 염기 편집제의 용도
US12406749B2 (en) 2017-12-15 2025-09-02 The Broad Institute, Inc. Systems and methods for predicting repair outcomes in genetic engineering
US12157760B2 (en) 2018-05-23 2024-12-03 The Broad Institute, Inc. Base editors and uses thereof
US12522807B2 (en) 2018-07-09 2026-01-13 The Broad Institute, Inc. RNA programmable epigenetic RNA modifiers and uses thereof
WO2020092453A1 (fr) 2018-10-29 2020-05-07 The Broad Institute, Inc. Éditeurs de nucléobases comprenant geocas9 et utilisations associées
US12351837B2 (en) 2019-01-23 2025-07-08 The Broad Institute, Inc. Supernegatively charged proteins and uses thereof
WO2020191233A1 (fr) 2019-03-19 2020-09-24 The Broad Institute, Inc. Procédés et compositions pour l'édition de séquences nucléotidiques
US12473543B2 (en) 2019-04-17 2025-11-18 The Broad Institute, Inc. Adenine base editors with reduced off-target effects
US12435330B2 (en) 2019-10-10 2025-10-07 The Broad Institute, Inc. Methods and compositions for prime editing RNA
IL297761A (en) 2020-05-08 2022-12-01 Broad Inst Inc Methods and compositions for simultaneously editing two helices of a designated double-helix nucleotide sequence

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BRPI0721895A2 (pt) * 2007-08-10 2014-04-08 Enza Zaden Beheer Bv Seqüência promotora de sp3d, constructo genético, método para provisão de plantas da família solanaceae possuindo um índice simpodial reduzido, método para aumento de rendimento de safra em uma planta da família solanaceae, planta, sementes e/ou outras partes de plantas, e planta da família solanaceae
BRPI0920872B1 (pt) * 2008-10-06 2018-06-19 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Polinucleotídeo isolado que codifica uma proteína de sft mutante e método para produzir uma planta híbrida

Also Published As

Publication number Publication date
WO2014081730A1 (fr) 2014-05-30
EP2922960A1 (fr) 2015-09-30
EP2922960A4 (fr) 2016-06-29

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