CA2904973A1 - Biomarqueurs bases sur le rapport et leur procedes d'utilisation - Google Patents

Biomarqueurs bases sur le rapport et leur procedes d'utilisation Download PDF

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Publication number
CA2904973A1
CA2904973A1 CA2904973A CA2904973A CA2904973A1 CA 2904973 A1 CA2904973 A1 CA 2904973A1 CA 2904973 A CA2904973 A CA 2904973A CA 2904973 A CA2904973 A CA 2904973A CA 2904973 A1 CA2904973 A1 CA 2904973A1
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CA
Canada
Prior art keywords
cancer
cancer associated
sample
protein
proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2904973A
Other languages
English (en)
Inventor
Stephen M. Hewitt
Joon-Yong Chung
Udayan GUHA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Health and Human Services
Original Assignee
US Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/841,176 external-priority patent/US20130210648A1/en
Application filed by US Department of Health and Human Services filed Critical US Department of Health and Human Services
Publication of CA2904973A1 publication Critical patent/CA2904973A1/fr
Abandoned legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5755—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the uterine cervix, uterine corpus or endometrium

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La présente invention concerne des compositions, procédés, trousses pour l'identification de biomolécules (par exemple, des protéines et des acides nucléiques) exprimés dans un échantillon biologique qui sont associés à la présence, au développement, ou à la progression d'une maladie (tel que le cancer), ou plus généralement la détermination de l'étiologie ou de facteurs de risques associés à une maladie. Des types d'échantillons analysés par les procédés selon la présente invention comprennent, entre autres, des blocs tissulaires d'archives qui ont été préservés dans une solution de fixation, des échantillons de biopsie tissulaire, des micro-matrices d'ADN tissulaires, et analogues. Les procédés selon la présente invention effectuent une corrélation de profils d'expression de biomolécules avec divers types de maladies, et permettent la détermination de taux de survie relatifs; selon certains modes de réalisation, les procédés permettent la détermination de taux de survie pour un sujet atteint de cancer. Selon d'autres modes de réalisation, la présente invention concerne des procédés pour l'évaluation de régimes thérapeutiques pour le traitement, tel que le traitement du cancer.
CA2904973A 2013-03-15 2014-03-12 Biomarqueurs bases sur le rapport et leur procedes d'utilisation Abandoned CA2904973A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/841,176 2013-03-15
US13/841,176 US20130210648A1 (en) 2009-01-14 2013-03-15 Ratio based biomarkers and methods of use thereof
PCT/US2014/024936 WO2014151079A2 (fr) 2013-03-15 2014-03-12 Biomarqueurs basés sur le rapport et leur procédés d'utilisation

Publications (1)

Publication Number Publication Date
CA2904973A1 true CA2904973A1 (fr) 2014-09-25

Family

ID=50693967

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2904973A Abandoned CA2904973A1 (fr) 2013-03-15 2014-03-12 Biomarqueurs bases sur le rapport et leur procedes d'utilisation

Country Status (3)

Country Link
EP (1) EP2972374A2 (fr)
CA (1) CA2904973A1 (fr)
WO (1) WO2014151079A2 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11320436B2 (en) 2020-07-16 2022-05-03 Immunovia Ab Methods, arrays and uses thereof
US11525832B2 (en) 2007-03-27 2022-12-13 Immunovia Ab Protein signature/markers for the detection of adenocarcinoma

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3635746A4 (fr) * 2017-04-28 2021-02-17 University of Southern California Système et procédé de prédiction de temps de survie
CN119199123A (zh) * 2024-10-21 2024-12-27 浙江大学 基于gls2功能的生物标志物在肿瘤免疫治疗诊断中的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5866366A (en) 1997-07-01 1999-02-02 Smithkline Beecham Corporation gidB
US6969615B2 (en) 1999-07-26 2005-11-29 20/20 Genesystems, Inc. Methods, devices, arrays and kits for detecting and analyzing biomolecules
WO2003029480A2 (fr) 2001-08-31 2003-04-10 The Government Of The United States Of America, Asrepresented By The Secretary Of The Department Of Health And Human Services Mesures de plusieurs molecules au moyen d'un cryotest
US20130210648A1 (en) * 2009-01-14 2013-08-15 The United States of America, as Represented by the Secretary, Department of Health and Human Services Ratio based biomarkers and methods of use thereof
CA2749601C (fr) * 2009-01-14 2020-07-21 Stephen M. Hewitt Biomarqueurs bases sur des taux et methodes d'utilisation associees
JP4782854B2 (ja) * 2009-03-10 2011-09-28 ナショナル ヤン−ミン ユニバーシティ 癌患者の潜在的転移能、予後、又は全生存を予測する方法
TW201122480A (en) * 2009-10-26 2011-07-01 Abbott Lab Diagnostic methods for determining prognosis of non-small cell lung cancer
US20120052508A1 (en) * 2010-08-27 2012-03-01 Rutgers, The State University Of New Jersey Genetic markers and diagnostic methods for resistance of breast cancer to hormonal therapies

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11525832B2 (en) 2007-03-27 2022-12-13 Immunovia Ab Protein signature/markers for the detection of adenocarcinoma
US11320436B2 (en) 2020-07-16 2022-05-03 Immunovia Ab Methods, arrays and uses thereof

Also Published As

Publication number Publication date
WO2014151079A8 (fr) 2015-04-30
WO2014151079A2 (fr) 2014-09-25
WO2014151079A3 (fr) 2015-03-05
EP2972374A2 (fr) 2016-01-20

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20190307

FZDE Discontinued

Effective date: 20210913