CA2919948A1 - Nouvelles quinazolones en tant qu'inhibiteurs de bromodomaine - Google Patents

Nouvelles quinazolones en tant qu'inhibiteurs de bromodomaine Download PDF

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CA2919948A1
CA2919948A1 CA2919948A CA2919948A CA2919948A1 CA 2919948 A1 CA2919948 A1 CA 2919948A1 CA 2919948 A CA2919948 A CA 2919948A CA 2919948 A CA2919948 A CA 2919948A CA 2919948 A1 CA2919948 A1 CA 2919948A1
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amino
compound
cancer
disease
dimethoxy
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CA2919948A
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CA2919948C (fr
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John Frederick Quinn
Vladimir Khlebnikov
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Zenith Epigenetics Ltd
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Zenith Capital Corp
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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CA2919948A 2013-07-31 2014-07-30 Nouvelles quinazolones en tant qu'inhibiteurs de bromodomaine Expired - Fee Related CA2919948C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361860403P 2013-07-31 2013-07-31
US61/860,403 2013-07-31
PCT/IB2014/002510 WO2015015318A2 (fr) 2013-07-31 2014-07-30 Nouvelles quinazolones en tant qu'inhibiteurs de bromodomaine

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CA2919948A1 true CA2919948A1 (fr) 2015-02-05
CA2919948C CA2919948C (fr) 2020-07-21

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CA2919948A Expired - Fee Related CA2919948C (fr) 2013-07-31 2014-07-30 Nouvelles quinazolones en tant qu'inhibiteurs de bromodomaine

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US (2) US9855271B2 (fr)
EP (1) EP3027604B1 (fr)
JP (1) JP6542212B2 (fr)
KR (1) KR20160038008A (fr)
CN (1) CN105593224B (fr)
AU (1) AU2014298051B2 (fr)
CA (1) CA2919948C (fr)
EA (1) EA201690087A1 (fr)
IL (1) IL243479B (fr)
WO (1) WO2015015318A2 (fr)

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AU2014298051B2 (en) 2018-11-15
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AU2014298051A1 (en) 2016-01-28
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HK1218547A1 (en) 2017-02-24
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