CA2937047A1 - Methodes d'ionisation de panaches laser par ionisation chimique a pression atmospherique - Google Patents
Methodes d'ionisation de panaches laser par ionisation chimique a pression atmospherique Download PDFInfo
- Publication number
- CA2937047A1 CA2937047A1 CA2937047A CA2937047A CA2937047A1 CA 2937047 A1 CA2937047 A1 CA 2937047A1 CA 2937047 A CA2937047 A CA 2937047A CA 2937047 A CA2937047 A CA 2937047A CA 2937047 A1 CA2937047 A1 CA 2937047A1
- Authority
- CA
- Canada
- Prior art keywords
- gas
- molecules
- gas jet
- system described
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000000065 atmospheric pressure chemical ionisation Methods 0.000 title claims abstract description 13
- 238000000034 method Methods 0.000 title claims abstract description 9
- 239000002019 doping agent Substances 0.000 claims abstract description 8
- 239000002184 metal Substances 0.000 claims description 9
- 239000000203 mixture Substances 0.000 claims description 4
- 238000000608 laser ablation Methods 0.000 claims description 3
- 238000004949 mass spectrometry Methods 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 2
- 239000007789 gas Substances 0.000 claims 13
- 239000012491 analyte Substances 0.000 claims 5
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 claims 3
- 238000002679 ablation Methods 0.000 claims 1
- 229910052756 noble gas Inorganic materials 0.000 claims 1
- 238000003795 desorption Methods 0.000 description 4
- 150000002500 ions Chemical class 0.000 description 4
- 238000013461 design Methods 0.000 description 2
- 238000000752 ionisation method Methods 0.000 description 2
- 239000011159 matrix material Substances 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 238000012631 diagnostic technique Methods 0.000 description 1
- 230000005672 electromagnetic field Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
- H01J49/0459—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for solid samples
- H01J49/0463—Desorption by laser or particle beam, followed by ionisation as a separate step
Landscapes
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Electron Tubes For Measurement (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA2937047A CA2937047A1 (fr) | 2016-07-25 | 2016-07-25 | Methodes d'ionisation de panaches laser par ionisation chimique a pression atmospherique |
| US16/338,286 US11583182B2 (en) | 2016-07-22 | 2017-07-24 | Method for multimodal tissue imaging based on resonance Raman effect on metal based MRI contrast agents and method for ionizing laser plumes through atmospheric pressure chemical ionization |
| GB1902539.4A GB2570055B (en) | 2016-07-22 | 2017-07-24 | Method for multimodal tissue imaging based on resonance Raman effect on metal based MRI contrast agents and method for ionizing laser plumes |
| PCT/CA2017/050887 WO2018014140A1 (fr) | 2016-07-22 | 2017-07-24 | Procédé d'imagerie de tissu multimodale basé sur l'effet raman de résonance sur des agents de contraste d'irm à base de métal et procédé d'ionisation de panaches laser par ionisation chimique à pression atmosphérique |
| CA2991191A CA2991191C (fr) | 2016-07-22 | 2017-07-24 | Procede d'imagerie de tissu multimodale base sur l'effet raman de resonance sur des agents de contraste d'irm a base de metal et procede d'ionisation de panaches laser par ionisation chimique a pression atmospherique |
| US18/083,443 US20230329558A1 (en) | 2016-07-22 | 2022-12-16 | Method for multimodal tissue imaging based on resonance raman effect on metal based mri contrast agents and method for ionizing laser plumes through atmospheric pressure chemical ionization |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA2937047A CA2937047A1 (fr) | 2016-07-25 | 2016-07-25 | Methodes d'ionisation de panaches laser par ionisation chimique a pression atmospherique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2937047A1 true CA2937047A1 (fr) | 2018-01-25 |
Family
ID=61008583
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2937047A Abandoned CA2937047A1 (fr) | 2016-07-22 | 2016-07-25 | Methodes d'ionisation de panaches laser par ionisation chimique a pression atmospherique |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2937047A1 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN119208123A (zh) * | 2024-09-20 | 2024-12-27 | 华中科技大学 | 飞秒激光辅助的化学电离方法 |
-
2016
- 2016-07-25 CA CA2937047A patent/CA2937047A1/fr not_active Abandoned
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN119208123A (zh) * | 2024-09-20 | 2024-12-27 | 华中科技大学 | 飞秒激光辅助的化学电离方法 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Dead |
Effective date: 20190725 |