CA2943348A1 - Compositions and methods for producing chemicals and derivatives thereof - Google Patents

Compositions and methods for producing chemicals and derivatives thereof Download PDF

Info

Publication number: CA2943348A1
Authority: CA; Canada
Prior art keywords: conversion; acid; ddg; fdca; glucose
Prior art date: 2014-03-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA2943348A

Other languages

English (en)

French (fr)

Inventor

Spiros Kambourakis

Benjamin M. GRIFFIN

Kevin V. Martin

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Viridos Inc

Original Assignee

Synthetic Genomics Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2014-03-21

Filing date

2015-03-20

Publication date

2015-09-24

2014-03-21 Priority claimed from US14/222,453 external-priority patent/US9528133B2/en

2015-03-20 Application filed by Synthetic Genomics Inc filed Critical Synthetic Genomics Inc

2015-09-24 Publication of CA2943348A1 publication Critical patent/CA2943348A1/en

Status Abandoned legal-status Critical Current

Links

238000000034 method Methods 0.000 title claims abstract description 162
239000000126 substance Substances 0.000 title claims abstract description 30
239000000203 mixture Substances 0.000 title description 13
238000006243 chemical reaction Methods 0.000 claims abstract description 346
CHTHALBTIRVDBM-UHFFFAOYSA-N furan-2,5-dicarboxylic acid Chemical compound OC(=O)C1=CC=C(C(O)=O)O1 CHTHALBTIRVDBM-UHFFFAOYSA-N 0.000 claims abstract description 229
230000002255 enzymatic effect Effects 0.000 claims abstract description 122
IZSRJDGCGRAUAR-MROZADKFSA-M 5-dehydro-D-gluconate Chemical compound OCC(=O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O IZSRJDGCGRAUAR-MROZADKFSA-M 0.000 claims abstract description 101
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims abstract description 91
239000000758 substrate Substances 0.000 claims abstract description 72
230000037361 pathway Effects 0.000 claims abstract description 66
239000008103 glucose Substances 0.000 claims abstract description 62
AEMOLEFTQBMNLQ-UHFFFAOYSA-N beta-D-galactopyranuronic acid Natural products OC1OC(C(O)=O)C(O)C(O)C1O AEMOLEFTQBMNLQ-UHFFFAOYSA-N 0.000 claims abstract description 59
AEMOLEFTQBMNLQ-BZINKQHNSA-N D-Guluronic Acid Chemical compound OC1O[C@H](C(O)=O)[C@H](O)[C@@H](O)[C@H]1O AEMOLEFTQBMNLQ-BZINKQHNSA-N 0.000 claims abstract description 58
239000002253 acid Substances 0.000 claims abstract description 53
AEMOLEFTQBMNLQ-CLQWQSTFSA-N l-iduronic acid Chemical compound O[C@H]1O[C@H](C(O)=O)[C@H](O)[C@@H](O)[C@@H]1O AEMOLEFTQBMNLQ-CLQWQSTFSA-N 0.000 claims abstract description 42
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YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 claims description 15
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RGHNJXZEOKUKBD-SQOUGZDYSA-M D-gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O RGHNJXZEOKUKBD-SQOUGZDYSA-M 0.000 description 17
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Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/58—Aldonic, ketoaldonic or saccharic acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/44—Polycarboxylic acids

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Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Life Sciences & Earth Sciences (AREA)
Wood Science & Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
Microbiology (AREA)
General Chemical & Material Sciences (AREA)
Biotechnology (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

CA2943348A 2014-03-21 2015-03-20 Compositions and methods for producing chemicals and derivatives thereof Abandoned CA2943348A1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US14/222,453 US9528133B2 (en)	2012-09-21	2014-03-21	Compositions and methods for producing chemicals and derivatives thereof
US14/222,453		2014-03-21
PCT/US2015/021848 WO2015143381A2 (en)	2014-03-21	2015-03-20	Compositions and methods for producing chemicals and derivatives thereof

Publications (1)

Publication Number	Publication Date
CA2943348A1 true CA2943348A1 (en)	2015-09-24

Family

ID=54145486

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA2943348A Abandoned CA2943348A1 (en)	2014-03-21	2015-03-20	Compositions and methods for producing chemicals and derivatives thereof

Country Status (7)

Country	Link
EP (1)	EP3119899A4 (de)
CN (1)	CN106414753A (de)
AU (1)	AU2015231000B2 (de)
BR (1)	BR112016021298A2 (de)
CA (1)	CA2943348A1 (de)
SG (1)	SG11201607745WA (de)
WO (1)	WO2015143381A2 (de)

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US10927363B2 (en)	2016-04-04	2021-02-23	Mie University	DNA sequence and expression vector for alginate lyase
CN107954959A (zh) *	2017-11-22	2018-04-24	南京工业大学	一种制备2,5-呋喃二甲酸及其前体物质的方法
CN109824630B (zh) *	2019-03-13	2020-08-04	浙江大学	一种甲酸供氢下木糖一锅法制备糠醇的方法
US20230272364A1 (en) *	2019-07-11	2023-08-31	Bp Corporation North America Inc.	Gluconate dehydratase enzymes and recombinant cells
CN113527374B (zh) *	2020-04-22	2025-12-02	中国科学院上海有机化学研究所	一种甘露糖醛酸寡糖的制备方法及其中间体
JP2024513175A (ja) *	2021-03-26	2024-03-22	アーチャー－ダニエルズ－ミッドランドカンパニー	酒石酸塩による阻害に耐性のある熱安定性ｄ－グルカル酸デヒドラターゼ
US12295919B2 (en)	2022-03-16	2025-05-13	Mie University	Methods of treatment and prevention using 4-deoxy-L-erythro-5-hexoseulose uronic acid

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US3184479A (en) *		1965-05-18		Process for the preparation of
JP2850515B2 (ja) *	1990-09-25	1999-01-27	東洋紡績株式会社	グルコースデヒドロゲナーゼおよびその製造法
AU2008249370B2 (en) *	2007-05-08	2013-09-05	Ensuiko Sugar Refining Co., Ltd.	Method for producing glucuronic acid by glucuronic acid fermentation
US8835147B2 (en) *	2008-04-04	2014-09-16	Massachusetts Institute Of Technology	Cellular production of glucaric acid through recombinant expression of uronate dehydrogenase and myo-inositol oxygenase
EP2281034B1 (de) *	2008-04-30	2015-10-21	DuPont Nutrition Biosciences ApS	Verfahren zur Verwendung von Pseudoglucanobacter saccharoketogenes Alcohol Dehydrogenase
FI20086236A0 (fi) *	2008-12-23	2008-12-23	Valtion Teknillinen	Heksuronihapon konversio heksarihapoksi
US8363666B2 (en) *	2010-02-22	2013-01-29	Cisco Technology, Inc.	Multiple network architecture providing for migration of devices
US9079844B2 (en) *	2012-04-04	2015-07-14	Stichting Dienst Landbouwkundig Onderzoek	Catalytic oxidation of uronic acids to aldaric acids
CN105026548B (zh) *	2012-06-04	2019-06-18	盐水港精糖株式会社	D-葡萄糖二酸生产菌及d-葡萄糖二酸的制造方法
BR112015006255A2 (pt) *	2012-09-21	2017-08-22	Synthetic Genomics Inc	Métodos para a produção de produtos químicos e derivados dos mesmos

2015
- 2015-03-20 CN CN201580021486.XA patent/CN106414753A/zh active Pending
- 2015-03-20 BR BR112016021298A patent/BR112016021298A2/pt not_active Application Discontinuation
- 2015-03-20 WO PCT/US2015/021848 patent/WO2015143381A2/en not_active Ceased
- 2015-03-20 EP EP15764217.4A patent/EP3119899A4/de not_active Withdrawn
- 2015-03-20 SG SG11201607745WA patent/SG11201607745WA/en unknown
- 2015-03-20 CA CA2943348A patent/CA2943348A1/en not_active Abandoned
- 2015-03-20 AU AU2015231000A patent/AU2015231000B2/en not_active Ceased

Also Published As

Publication number	Publication date
EP3119899A4 (de)	2017-11-29
WO2015143381A3 (en)	2015-11-12
AU2015231000A1 (en)	2016-10-13
AU2015231000B2 (en)	2017-10-26
EP3119899A2 (de)	2017-01-25
WO2015143381A2 (en)	2015-09-24
BR112016021298A2 (pt)	2017-10-03
SG11201607745WA (en)	2016-11-29
CN106414753A (zh)	2017-02-15

Legal Events

Date	Code	Title	Description
2020-11-07	FZDE	Discontinued	Effective date: 20200831

Publication	Publication Date	Title
US9506090B2 (en)	2016-11-29	Method for synthesizing FDCA and derivates thereof
US9528133B2 (en)	2016-12-27	Compositions and methods for producing chemicals and derivatives thereof
AU2015231000B2 (en)	2017-10-26	Compositions and methods for producing chemicals and derivatives thereof
JP5735493B2 (ja)	2015-06-17	アンブロキサンの生物触媒的生産
US20110151530A1 (en)	2011-06-23	Enzymatic production of 2-hydroxy-isobutyrate (2-hiba)
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