CA2974884C - Construction a epitopes multiples - Google Patents

Construction a epitopes multiples

Info

Publication number
CA2974884C
CA2974884C CA2974884A CA2974884A CA2974884C CA 2974884 C CA2974884 C CA 2974884C CA 2974884 A CA2974884 A CA 2974884A CA 2974884 A CA2974884 A CA 2974884A CA 2974884 C CA2974884 C CA 2974884C
Authority
CA
Canada
Prior art keywords
seq
construct according
mice
epitope
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2974884A
Other languages
English (en)
Other versions
CA2974884A1 (fr
Inventor
Vijay Kakkar
Xinjie Lu
Original Assignee
Thrombosis Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1501354.3A external-priority patent/GB201501354D0/en
Priority claimed from GBGB1510195.9A external-priority patent/GB201510195D0/en
Application filed by Thrombosis Research Institute filed Critical Thrombosis Research Institute
Priority claimed from PCT/GB2016/050150 external-priority patent/WO2016120596A1/fr
Publication of CA2974884A1 publication Critical patent/CA2974884A1/fr
Application granted granted Critical
Publication of CA2974884C publication Critical patent/CA2974884C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Abstract

L'invention concerne des constructions à épitopes multiples, des compositions immunogènes et de vaccin comprenant des molécules de recombinaison dans lesquelles sont insérés des épitopes multiples et différents provenant d'une variété d'antigènes, les déterminants antigéniques étant associés à différentes voies conduisant à l'athérosclérose. En particulier, l'invention concerne des compositions visant à déclencher une réponse immunitaire contre des antigènes et des agents pathogènes impliqués dans le développement de l'athérosclérose, l'invention concernant, entre autres, des procédés de traitement et/ou de prévention de cette maladie et des produits de protéine de recombinaison.
CA2974884A 2015-01-27 2016-01-25 Construction a epitopes multiples Active CA2974884C (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB1501354.4 2015-01-27
GBGB1501354.3A GB201501354D0 (en) 2015-01-27 2015-01-27 Multi-epitopic construct
GBGB1510195.9A GB201510195D0 (en) 2015-06-11 2015-06-11 Multi-epitopic construct
GB1510195.9 2015-06-11
PCT/GB2016/050150 WO2016120596A1 (fr) 2015-01-27 2016-01-25 Construction à épitopes multiples

Publications (2)

Publication Number Publication Date
CA2974884A1 CA2974884A1 (fr) 2016-08-04
CA2974884C true CA2974884C (fr) 2026-04-21

Family

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