CA2981365C - Imidazolonylquinoleines et leur utilisation comme inhibiteurs des kinases atm - Google Patents

Imidazolonylquinoleines et leur utilisation comme inhibiteurs des kinases atm

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Publication number
CA2981365C
CA2981365C CA2981365A CA2981365A CA2981365C CA 2981365 C CA2981365 C CA 2981365C CA 2981365 A CA2981365 A CA 2981365A CA 2981365 A CA2981365 A CA 2981365A CA 2981365 C CA2981365 C CA 2981365C
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Canada
Prior art keywords
pyrazol
methyl
methoxy
fluoro
methy1
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CA2981365A
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English (en)
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CA2981365A1 (fr
Inventor
Thomas Fuchss
Kai Schiemann
Original Assignee
Merck Patent GmbH
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Priority claimed from PCT/EP2016/000542 external-priority patent/WO2016155884A1/fr
Publication of CA2981365A1 publication Critical patent/CA2981365A1/fr
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Publication of CA2981365C publication Critical patent/CA2981365C/fr
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Abstract

Il est décrit des composés de formule (I), par exemple des composés de formule (IV) : (voir la formule IV). Les composés sont des inhibiteurs de la kinase d’ataxie-télangiectasie mutée et peuvent être utilisés, entre autres, pour traiter le cancer.
CA2981365A 2015-04-02 2016-03-31 Imidazolonylquinoleines et leur utilisation comme inhibiteurs des kinases atm Active CA2981365C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15000968.6 2015-04-02
EP15000968 2015-04-02
PCT/EP2016/000542 WO2016155884A1 (fr) 2015-04-02 2016-03-31 Imidazolonylquinoléines et leur utilisation comme inhibiteurs des kinases atm

Publications (2)

Publication Number Publication Date
CA2981365A1 CA2981365A1 (fr) 2016-10-06
CA2981365C true CA2981365C (fr) 2026-01-13

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