CA2986796C - Anticorps anti-ntb-a ainsi que compositions et procedes associes - Google Patents

Anticorps anti-ntb-a ainsi que compositions et procedes associes

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Publication number
CA2986796C
CA2986796C CA2986796A CA2986796A CA2986796C CA 2986796 C CA2986796 C CA 2986796C CA 2986796 A CA2986796 A CA 2986796A CA 2986796 A CA2986796 A CA 2986796A CA 2986796 C CA2986796 C CA 2986796C
Authority
CA
Canada
Prior art keywords
antibody
ntb
drug conjugate
solvate
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2986796A
Other languages
English (en)
Other versions
CA2986796A1 (fr
Inventor
Timothy Lewis
Lori Westendorf
Django Sussman
Che-Leung Law
Original Assignee
Seagen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seagen Inc filed Critical Seagen Inc
Priority claimed from PCT/US2016/040307 external-priority patent/WO2017004330A1/fr
Publication of CA2986796A1 publication Critical patent/CA2986796A1/fr
Application granted granted Critical
Publication of CA2986796C publication Critical patent/CA2986796C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Abstract

La présente invention concerne des anticorps, y compris des conjugués anticorps-médicament qui se lient spécifiquement au NTB-A. L'invention concerne également des procédés d'utilisation des anticorps anti-NTB-A pour détecter ou moduler l'activité (<i />par exemple inhiber la prolifération) d'une cellule exprimant le NTB-A, ainsi que pour diagnostiquer ou traiter des maladies ou des affections (<i />par exemple le cancer) associées aux cellules exprimant le NTB-A, comme le myélome multiple, le lymphome non hodgkinien et la leucémie myéloïde aiguë.
CA2986796A 2015-06-30 2016-06-30 Anticorps anti-ntb-a ainsi que compositions et procedes associes Active CA2986796C (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562186596P 2015-06-30 2015-06-30
US62/186,596 2015-06-30
US201662321849P 2016-04-13 2016-04-13
US62/321,849 2016-04-13
PCT/US2016/040307 WO2017004330A1 (fr) 2015-06-30 2016-06-30 Anticorps anti-ntb-a ainsi que compositions et procédés associés

Publications (2)

Publication Number Publication Date
CA2986796A1 CA2986796A1 (fr) 2017-01-05
CA2986796C true CA2986796C (fr) 2025-09-23

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