CA2996386C - Procede ameliore pour fabriquer de la fucoxanthine et/ou des polysaccharides a partir de microalgues - Google Patents

Procede ameliore pour fabriquer de la fucoxanthine et/ou des polysaccharides a partir de microalgues Download PDF

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Publication number
CA2996386C
CA2996386C CA2996386A CA2996386A CA2996386C CA 2996386 C CA2996386 C CA 2996386C CA 2996386 A CA2996386 A CA 2996386A CA 2996386 A CA2996386 A CA 2996386A CA 2996386 C CA2996386 C CA 2996386C
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fucoxanthin
microalgae
extraction
polysaccharides
rich
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CA2996386A1 (fr
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Oran Ayalon
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Algahealth (ah) Ltd
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Algahealth (ah) Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/04—Solvent extraction of solutions which are liquid
    • B01D11/0403—Solvent extraction of solutions which are liquid with a supercritical fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/04—Solvent extraction of solutions which are liquid
    • B01D11/0492—Applications, solvents used
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/16—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by esterified hydroxyl radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/02—Separating microorganisms from their culture media
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12—Unicellular algae; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Botany (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Molecular Biology (AREA)
  • Psychiatry (AREA)
  • Analytical Chemistry (AREA)

Abstract

La présente invention concerne un procédé de production de fucoxanthine et/ou de polysaccharides à partir de microalgues, et l'utilisation de fucoxanthine purifiée obtenue par ce procédé, dans des produits pharmaceutiques, cosmétiques, nutraceutiques, et dans des compositions alimentaires.
CA2996386A 2015-08-28 2016-08-23 Procede ameliore pour fabriquer de la fucoxanthine et/ou des polysaccharides a partir de microalgues Active CA2996386C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562211094P 2015-08-28 2015-08-28
US62/211,094 2015-08-28
PCT/IL2016/050917 WO2017037692A1 (fr) 2015-08-28 2016-08-23 Procédé amélioré pour fabriquer de la fucoxanthine et/ou des polysaccharides à partir de microalgues

Publications (2)

Publication Number Publication Date
CA2996386A1 CA2996386A1 (fr) 2017-03-09
CA2996386C true CA2996386C (fr) 2023-10-03

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CA2996386A Active CA2996386C (fr) 2015-08-28 2016-08-23 Procede ameliore pour fabriquer de la fucoxanthine et/ou des polysaccharides a partir de microalgues

Country Status (9)

Country Link
US (1) US11197843B2 (fr)
EP (1) EP3340976A4 (fr)
JP (1) JP6931930B2 (fr)
KR (1) KR102626965B1 (fr)
CN (1) CN108024988A (fr)
AU (1) AU2016314624B2 (fr)
CA (1) CA2996386C (fr)
MX (1) MX389515B (fr)
WO (1) WO2017037692A1 (fr)

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CN107951812A (zh) * 2017-12-18 2018-04-24 丁玉琴 一种爽肤水及其制备方法
KR102546266B1 (ko) * 2018-06-08 2023-06-22 파이코일바이오텍코리아 (주) 미세조류로부터 특정 고분자다당류를 선택적으로 수득하기 위한 방법
CN109566393A (zh) * 2018-12-14 2019-04-05 浙江海洋大学 用于提取多糖的海藻的培养方法
KR102249424B1 (ko) * 2019-09-19 2021-05-07 훠리스트 주식회사 미세조류 심바이오디니움 속으로부터 추출된 유효성분을 함유하는 자외선 차단용 조성물 및 그 제조방법
CN112972452B (zh) * 2021-03-05 2022-10-11 中国海洋大学 岩藻黄素、岩藻黄醇在提升人体dha及epa含量制品中的应用
KR102882605B1 (ko) * 2022-04-26 2025-11-06 주식회사 마이크로알지에스크어스 니츠시아 에스피 유래 푸코잔틴 함유 추출물을 활성성분으로 함유하는 간세포 보호용 조성물 및 이의 생산방법
KR102882611B1 (ko) * 2022-04-27 2025-11-06 주식회사 마이크로알지에스크어스 케토세로스 그라실리스 유래 푸코잔틴 함유 추출물을 활성성분으로 함유하는 간세포 보호용 조성물 및 이의 생산방법
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KR102882609B1 (ko) * 2022-04-27 2025-11-06 주식회사 마이크로알지에스크어스 페오닥틸럼 트리코뉴튬 유래 푸코잔틴 함유 추출물을 활성성분으로 함유하는 간세포 보호용 조성물 및 이의 생산방법
KR102882613B1 (ko) * 2022-04-27 2025-11-06 주식회사 마이크로알지에스크어스 아이소크라이시스 갈바나 유래 푸코잔틴 함유 추출물을 활성성분으로 함유하는 간세포 보호용 조성물 및 이의 생산방법
CN115011641B (zh) * 2022-05-25 2024-06-25 重庆理工大学 一种通过壳聚糖强化微藻产油与固碳的方法
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Publication number Publication date
AU2016314624A1 (en) 2018-03-15
KR102626965B1 (ko) 2024-01-18
NZ740062A (en) 2024-07-05
WO2017037692A1 (fr) 2017-03-09
JP6931930B2 (ja) 2021-09-08
US11197843B2 (en) 2021-12-14
KR20180043342A (ko) 2018-04-27
JP2019506133A (ja) 2019-03-07
EP3340976A1 (fr) 2018-07-04
MX389515B (es) 2025-03-20
CA2996386A1 (fr) 2017-03-09
US20200230098A1 (en) 2020-07-23
MX2018002318A (es) 2018-08-15
CN108024988A (zh) 2018-05-11
AU2016314624B2 (en) 2021-03-04
EP3340976A4 (fr) 2019-04-17

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