CA3010013C - Compositions et methodes de recherche de mutations dans le cancer de la thyroide - Google Patents

Compositions et methodes de recherche de mutations dans le cancer de la thyroide

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Publication number
CA3010013C
CA3010013C CA3010013A CA3010013A CA3010013C CA 3010013 C CA3010013 C CA 3010013C CA 3010013 A CA3010013 A CA 3010013A CA 3010013 A CA3010013 A CA 3010013A CA 3010013 C CA3010013 C CA 3010013C
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Canada
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exon
amplicons
braf
ret
thada
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CA3010013A
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English (en)
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CA3010013A1 (fr
Inventor
Shih-Min Cheng
Joseph J. CATANESE
Andrew Grupe
Feras Hantash
Frederic M. WALDMAN
Kevin Qu
Original Assignee
Quest Diagnostics Investments LLC
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Priority claimed from PCT/US2016/069478 external-priority patent/WO2017117523A1/fr
Publication of CA3010013A1 publication Critical patent/CA3010013A1/fr
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Publication of CA3010013C publication Critical patent/CA3010013C/fr
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Abstract

La présente invention concerne des méthodes pour déterminer si un patient ayant des nodules thyroïdiens avec cytologie indéterminée tirera profit d'une chirurgie diagnostique, par exemple, une lobectomie.<i /> Ces méthodes sont fondées sur le dépistage de nodules thyroïdiens chez un patient et sur la détection de modifications dans des séquences d'acide nucléique cibles correspondant à un ensemble spécifique de gènes associés au cancer. L'invention concerne également des nécessaires destinés à être utilisés pour la mise en pratique de ces méthodes.
CA3010013A 2015-12-31 2016-12-30 Compositions et methodes de recherche de mutations dans le cancer de la thyroide Active CA3010013C (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562273783P 2015-12-31 2015-12-31
US62/273,783 2015-12-31
US201662439572P 2016-12-28 2016-12-28
US62/439,572 2016-12-28
PCT/US2016/069478 WO2017117523A1 (fr) 2015-12-31 2016-12-30 Compositions et méthodes de recherche de mutations dans le cancer de la thyroïde

Publications (2)

Publication Number Publication Date
CA3010013A1 CA3010013A1 (fr) 2017-07-06
CA3010013C true CA3010013C (fr) 2025-09-09

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