CA3017603C - Procedes d'expansion et d'activation de lymphocytes t
- Google Patents
Procedes d'expansion et d'activation de lymphocytes t
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Publication number
CA3017603C
CA3017603CCA3017603ACA3017603ACA3017603CCA 3017603 CCA3017603 CCA 3017603CCA 3017603 ACA3017603 ACA 3017603ACA 3017603 ACA3017603 ACA 3017603ACA 3017603 CCA3017603 CCA 3017603C
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CA
Canada
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cells
baff
cell
activated
population
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Application filed by Wisconsin Alumni Research FoundationfiledCriticalWisconsin Alumni Research Foundation
Priority claimed from PCT/US2017/022260external-prioritypatent/WO2017160806A1/fr
Publication of CA3017603A1publicationCriticalpatent/CA3017603A1/fr
Application grantedgrantedCritical
Publication of CA3017603CpublicationCriticalpatent/CA3017603C/fr
La présente invention concerne des procédés, des cellules et des compositions pour préparer des populations de lymphocytes T et des compositions pour une thérapie cellulaire adoptive. En particulier, l'invention concerne des procédés d'expansion et d'activation efficaces de populations de lymphocytes T pour l'ingénierie génétique et des immunothérapies de lymphocytes T adoptives. L'invention concerne également des cellules et des compositions produites selon les procédés et leurs procédés d'utilisation.
CA3017603A2016-03-142017-03-14Procedes d'expansion et d'activation de lymphocytes t
ActiveCA3017603C
(fr)
Exogenous IFN‐γ ex vivo shapes the alloreactive T‐cell repertoire by inhibition of Th17 responses and generation of functional Foxp3+ regulatory T cells
The role of the immune system in the immunopathogenesis of autoimmune diseases and the therapeutic modulation of autoimmune reaction by tolerogenic dendritic cells
In vitro characterisation and expansion of human regulatory T cells for their in vivo application in the induction of tolerance in haematopoietic stem cell and solid organ transplantation