CA3017753A1 - Procedes et systemes de traitement et d'analyse de dosages multiples - Google Patents

Procedes et systemes de traitement et d'analyse de dosages multiples Download PDF

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Publication number
CA3017753A1
CA3017753A1 CA3017753A CA3017753A CA3017753A1 CA 3017753 A1 CA3017753 A1 CA 3017753A1 CA 3017753 A CA3017753 A CA 3017753A CA 3017753 A CA3017753 A CA 3017753A CA 3017753 A1 CA3017753 A1 CA 3017753A1
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CA
Canada
Prior art keywords
nucleic acid
assay
sample
target nucleic
different target
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA3017753A
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English (en)
Other versions
CA3017753C (fr
Inventor
Frank PAWLOWSKI
Joseph P. Skinner
Jack Kessler
Sonal Sadaria NANA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Molecular Inc
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Abbott Molecular Inc
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Application filed by Abbott Molecular Inc filed Critical Abbott Molecular Inc
Publication of CA3017753A1 publication Critical patent/CA3017753A1/fr
Application granted granted Critical
Publication of CA3017753C publication Critical patent/CA3017753C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • B01L9/523—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for multisample carriers, e.g. used for microtitration plates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178—Special arrangements of analysers
    • G01N2035/00326—Analysers with modular structure
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

La présente invention concerne des procédés de traitement de dosages multiples et d'analyse de dosages multiples. Un tel traitement de dosages multiples et une telle analyse de dosages multiples concernent la détection automatisée d'acides nucléiques cibles, par exemple tels qu'ils sont effectués dans le contexte clinique à des fins de diagnostic. L'invention concerne également des protocoles de synchronisation d'essais classiques dérivés de divers protocoles individuels d'amplification et d'analyse des acides nucléiques et modifiés pour éviter un conflit de ressource. La présente invention concerne également des systèmes et des dispositifs pour mettre en uvre les procédés de l'invention.
CA3017753A 2016-03-15 2017-03-15 Procedes et systemes de traitement et d'analyse de dosages multiples Active CA3017753C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662308625P 2016-03-15 2016-03-15
US62/308,625 2016-03-15
PCT/US2017/022502 WO2017160979A1 (fr) 2016-03-15 2017-03-15 Procédés et systèmes de traitement et d'analyse de dosages multiples

Publications (2)

Publication Number Publication Date
CA3017753A1 true CA3017753A1 (fr) 2017-09-21
CA3017753C CA3017753C (fr) 2023-08-01

Family

ID=59851943

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3017753A Active CA3017753C (fr) 2016-03-15 2017-03-15 Procedes et systemes de traitement et d'analyse de dosages multiples

Country Status (7)

Country Link
US (3) US11104962B2 (fr)
EP (2) EP4095257B1 (fr)
JP (3) JP7450336B2 (fr)
CN (1) CN109477131B (fr)
CA (1) CA3017753C (fr)
ES (2) ES3041372T3 (fr)
WO (1) WO2017160979A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017160980A1 (fr) 2016-03-15 2017-09-21 Abbott Laboratories Dispositifs, systèmes et procédés de traitement d'échantillons
ES3041372T3 (en) * 2016-03-15 2025-11-11 Abbott Molecular Inc Systems of multi-assay processing and analysis
CN109477849B (zh) 2016-03-15 2022-10-21 雅培分子公司 自动分析系统和方法
US20170266668A1 (en) 2016-03-15 2017-09-21 Abbott Laboratories Nucleic Acid Amplification and Detection Devices, Systems and Methods
EP3731959B1 (fr) 2017-12-29 2025-10-08 Clear Labs, Inc. Dispositif automatisé d'amorçage et de chargement de bibliothèque
CN111826463A (zh) * 2019-12-31 2020-10-27 深圳市人民医院 用于五种重要节肢/啮齿媒介传播病毒检测的引物探针组合、试剂盒及其应用

Family Cites Families (24)

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DE3175603D1 (en) * 1981-08-06 1987-01-02 Toyo Rubber Chemical Ind Co Method for manufacturing low density rubber foamed body
EP1499872B1 (fr) * 2002-04-26 2015-11-18 Ventana Medical Systems, Inc. Appareil automatise pour pathologie moleculaire a porte-lames fixes
AU2003900810A0 (en) * 2003-02-24 2003-03-13 Vision Biosystems Limited Method of scheduling
AU2005299590B2 (en) * 2004-10-27 2010-09-16 Cepheid Closed-system multi-stage nucleic acid amplification reactions
WO2007002580A2 (fr) * 2005-06-23 2007-01-04 Bioveris Corporation Dispositif de detection et procedes associes a ce dispositif
US8883509B2 (en) * 2007-07-10 2014-11-11 Ventana Medical Systems, Inc. Apparatus and method for biological sample processing
WO2010036287A1 (fr) * 2008-09-24 2010-04-01 Pacific Biosciences Of California, Inc. Détection intermittente durant des réactions analytiques
GB0818609D0 (en) * 2008-10-10 2008-11-19 Univ Hull apparatus and method
EP2752668A3 (fr) 2010-07-23 2014-10-15 Beckman Coulter, Inc. Système ou procédé comprenant des unités analytiques
WO2012092259A1 (fr) * 2010-12-27 2012-07-05 Ibis Biosciences, Inc. Quantification d'échantillons ayant des titres élevés par pcr numérique
CN103534360A (zh) * 2011-03-18 2014-01-22 伯乐生命医学产品有限公司 借助对信号的组合使用进行的多重数字分析
ES2769028T3 (es) * 2011-04-15 2020-06-24 Becton Dickinson Co Termociclador microfluídico de barrido en tiempo real
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KR101481054B1 (ko) * 2011-11-15 2015-01-14 한국기계연구원 핵산 자동 분석 장치
JP6087138B2 (ja) 2012-12-28 2017-03-01 株式会社日立ハイテクノロジーズ 遺伝子検査装置、遺伝子検査方法及びプログラム
EP3547181B1 (fr) * 2013-07-25 2023-01-11 Labrador Diagnostics LLC Systèmes et procédés pour un laboratoire clinique réparti
AU2015239720B2 (en) 2014-03-31 2019-07-11 Ventana Medical Systems, Inc. Automated specimen processing systems and multistep processing of microscope slides
LU92552B1 (de) * 2014-09-22 2016-03-23 Glycotope Gmbh Verfahren zum nachweis von nukleinsäuren in proben mit biologischem material
WO2017160980A1 (fr) 2016-03-15 2017-09-21 Abbott Laboratories Dispositifs, systèmes et procédés de traitement d'échantillons
JP6894453B2 (ja) 2016-03-15 2021-06-30 アボット モレキュラー インク． 試料調製カートリッジ及びその使用方法
ES3041372T3 (en) * 2016-03-15 2025-11-11 Abbott Molecular Inc Systems of multi-assay processing and analysis
CN109477849B (zh) * 2016-03-15 2022-10-21 雅培分子公司 自动分析系统和方法
US20170266668A1 (en) 2016-03-15 2017-09-21 Abbott Laboratories Nucleic Acid Amplification and Detection Devices, Systems and Methods
WO2017161058A1 (fr) 2016-03-15 2017-09-21 Abbott Laboratories Systèmes d'enceinte de réaction et procédés et systèmes pour les utiliser

Also Published As

Publication number Publication date
US20170335408A1 (en) 2017-11-23
JP2019512264A (ja) 2019-05-16
JP2024138269A (ja) 2024-10-08
ES2923792T3 (es) 2022-09-30
WO2017160979A1 (fr) 2017-09-21
US11104962B2 (en) 2021-08-31
CN109477131B (zh) 2022-08-16
EP3430169B1 (fr) 2022-06-22
JP7450336B2 (ja) 2024-03-15
EP4095257B1 (fr) 2025-07-30
EP3430169A4 (fr) 2019-10-30
US20250230509A1 (en) 2025-07-17
CA3017753C (fr) 2023-08-01
EP4095257A1 (fr) 2022-11-30
JP2022106827A (ja) 2022-07-20
JP7585256B2 (ja) 2024-11-18
EP3430169A1 (fr) 2019-01-23
CN109477131A (zh) 2019-03-15
US12241131B2 (en) 2025-03-04
ES3041372T3 (en) 2025-11-11
US20220010387A1 (en) 2022-01-13

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