CA3023460C - Inhibiteurs de cdk4/6 pour le traitement des maladies hyper-proliferatives
- Google Patents
Inhibiteurs de cdk4/6 pour le traitement des maladies hyper-proliferatives
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Publication number
CA3023460C
CA3023460CCA3023460ACA3023460ACA3023460CCA 3023460 CCA3023460 CCA 3023460CCA 3023460 ACA3023460 ACA 3023460ACA 3023460 ACA3023460 ACA 3023460ACA 3023460 CCA3023460 CCA 3023460C
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CA
Canada
Prior art keywords
compound
pharmaceutically acceptable
acceptable salt
alkyl
amino
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application filed by Fochon Pharmaceuticals LtdfiledCriticalFochon Pharmaceuticals Ltd
Priority claimed from PCT/CN2017/083162external-prioritypatent/WO2017193872A1/fr
Publication of CA3023460A1publicationCriticalpatent/CA3023460A1/fr
Application grantedgrantedCritical
Publication of CA3023460CpublicationCriticalpatent/CA3023460C/fr
Il est décrit des inhibiteurs de CDK4 et/ou CDK6. Les composés - comme l’exemple 5 affiché ici - peuvent être utiles pour le traitement de maladies hyperprolifératives comme le cancer ou l’inflammation. (voir l’exemple 5)
CA3023460A2016-05-072017-05-05Inhibiteurs de cdk4/6 pour le traitement des maladies hyper-proliferatives
ActiveCA3023460C
(fr)
Composés de (2-azabicyclo [3.1.0] hexan-2-yl) pyrazolo [1, 5-a] pyrimidine et imidazo [1, 2-b] pyridazine substitués en tant qu'inhibiteurs de kinases trk