CA3024281C - Intermediaires pour la synthese de derives de l'acide biliaire, en particulier de l'acide obeticholique - Google Patents

Intermediaires pour la synthese de derives de l'acide biliaire, en particulier de l'acide obeticholique

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Publication number
CA3024281C
CA3024281C CA3024281A CA3024281A CA3024281C CA 3024281 C CA3024281 C CA 3024281C CA 3024281 A CA3024281 A CA 3024281A CA 3024281 A CA3024281 A CA 3024281A CA 3024281 C CA3024281 C CA 3024281C
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Canada
Prior art keywords
compound
general formula
group
alkyl
compounds
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
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CA3024281A
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English (en)
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CA3024281A1 (fr
Inventor
Alexander Charles Weymouth-Wilson
Zofia KOMSTA
Laura WALLIS
Timothy Evans
Ieuan DAVIES
Carl OTTER
Rhys BATCHELOR
Original Assignee
Nzp Uk Ltd
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Priority claimed from GBGB1608777.7A external-priority patent/GB201608777D0/en
Application filed by Nzp Uk Ltd filed Critical Nzp Uk Ltd
Publication of CA3024281A1 publication Critical patent/CA3024281A1/fr
Application granted granted Critical
Publication of CA3024281C publication Critical patent/CA3024281C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Abstract

La présente invention concerne des composés de formule (I), dans lesquels R1,R2, R3, R4, R5, R6 et Y sont tels que définis ici. Les composés sont des intermédiaires dans la synthèse des acides biliaires synthétiques qui sont utiles dans le traitement d'affections tels qu'une maladie du foie.
CA3024281A 2016-05-18 2017-05-18 Intermediaires pour la synthese de derives de l'acide biliaire, en particulier de l'acide obeticholique Active CA3024281C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1608777.7 2016-05-18
GBGB1608777.7A GB201608777D0 (en) 2016-05-18 2016-05-18 Compounds
PCT/GB2017/051385 WO2017199033A1 (fr) 2016-05-18 2017-05-18 Intermédiaires pour la synthèse de dérivés de l'acide biliaire, en particulier de l'acide obéticholique

Publications (2)

Publication Number Publication Date
CA3024281A1 CA3024281A1 (fr) 2017-11-23
CA3024281C true CA3024281C (fr) 2025-12-30

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