CA3028721C - Compositions et methodes pour administrer des agents biomacromoleculaires - Google Patents

Compositions et methodes pour administrer des agents biomacromoleculaires

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Publication number
CA3028721C
CA3028721C CA3028721A CA3028721A CA3028721C CA 3028721 C CA3028721 C CA 3028721C CA 3028721 A CA3028721 A CA 3028721A CA 3028721 A CA3028721 A CA 3028721A CA 3028721 C CA3028721 C CA 3028721C
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CA
Canada
Prior art keywords
seq
antigen
apolipoprotein
nanoparticle
peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3028721A
Other languages
English (en)
Other versions
CA3028721A1 (fr
Inventor
James J. Moon
Anna A. Schwendeman
Rui KUAI
Jutaek Nam
Original Assignee
University of Michigan System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Michigan System filed Critical University of Michigan System
Priority claimed from PCT/US2017/038333 external-priority patent/WO2017223085A2/fr
Publication of CA3028721A1 publication Critical patent/CA3028721A1/fr
Application granted granted Critical
Publication of CA3028721C publication Critical patent/CA3028721C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Abstract

La présente invention concerne des nanoparticules associées (par exemple, complexées, conjuguées, encapsulées, absorbées, adsorbées, mélangées) à des agents biomacromoléculaires conçus pour traiter, prévenir ou soulager divers types de troubles, ainsi que des procédés de synthèse de celles-ci. La présente invention concerne en particulier des compositions comprenant des nanoparticules (par exemple, des lipoprotéines synthétiques haute densité (sHDL)) associées (par exemple, complexées, conjuguées, encapsulées, absorbées, adsorbées, mélangées) à des agents biomacromoléculaires (par exemple, un acide nucléique, des peptides, des glycolipides, etc.), des procédés de synthèse desdites nanoparticules, ainsi que des systèmes et des méthodes faisant intervenir lesdites nanoparticules (par exemple, dans des réglages diagnostiques et/ou thérapeutiques).
CA3028721A 2016-06-20 2017-06-20 Compositions et methodes pour administrer des agents biomacromoleculaires Active CA3028721C (fr)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662352182P 2016-06-20 2016-06-20
US62/352,182 2016-06-20
US201662398330P 2016-09-22 2016-09-22
US62/398,330 2016-09-22
US201662436865P 2016-12-20 2016-12-20
US62/436,865 2016-12-20
PCT/US2017/038333 WO2017223085A2 (fr) 2016-06-20 2017-06-20 Compositions et méthodes pour administrer des agents biomacromoléculaires

Publications (2)

Publication Number Publication Date
CA3028721A1 CA3028721A1 (fr) 2017-12-28
CA3028721C true CA3028721C (fr) 2026-05-12

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