CA3042004C - Composes de benzenesulfonamide et leur utilisation en tant qu'agents therapeutiques - Google Patents

Composes de benzenesulfonamide et leur utilisation en tant qu'agents therapeutiques

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Publication number
CA3042004C
CA3042004C CA3042004A CA3042004A CA3042004C CA 3042004 C CA3042004 C CA 3042004C CA 3042004 A CA3042004 A CA 3042004A CA 3042004 A CA3042004 A CA 3042004A CA 3042004 C CA3042004 C CA 3042004C
Authority
CA
Canada
Prior art keywords
amino
benzenesulfonamide
difluoro
thiazol
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3042004A
Other languages
English (en)
Other versions
CA3042004A1 (fr
Inventor
David Earl Bogucki
Sultan Chowdhury
Qi Jia
Alla Yurevna Zenova
Jean-Christophe Andrez
Michael Scott Wilson
Christoph Martin Dehnhardt
Thilo Focken
Michael Edward GRIMWOOD
Shannon Marie Decker
Kristen Nicole Burford
Charles Jay Cohen
Robert Joseph Devita
James Roy Empfield
Syed Abid Hasan
Jr. Johnson James Philip
Original Assignee
Xenon Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xenon Pharmaceuticals Inc filed Critical Xenon Pharmaceuticals Inc
Priority claimed from PCT/US2017/033666 external-priority patent/WO2018106284A1/fr
Publication of CA3042004A1 publication Critical patent/CA3042004A1/fr
Application granted granted Critical
Publication of CA3042004C publication Critical patent/CA3042004C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Abstract

La présente invention concerne des composés benzènesulfonamides, tels que des stéréoisomères, des énantiomères, des tautomères de ceux-ci ou leurs mélanges, ou leurs sels, solvates ou promédicaments pharmaceutiquement acceptables, pour traiter des maladies ou des affections associées aux canaux sodiques sensibles à la tension, telles que l'épilepsie.
CA3042004A 2016-12-09 2017-05-19 Composes de benzenesulfonamide et leur utilisation en tant qu'agents therapeutiques Active CA3042004C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662432169P 2016-12-09 2016-12-09
US62/432,169 2016-12-09
PCT/US2017/033666 WO2018106284A1 (fr) 2016-12-09 2017-05-19 Composés de benzènesulfonamide et leur utilisation en tant qu'agents thérapeutiques

Publications (2)

Publication Number Publication Date
CA3042004A1 CA3042004A1 (fr) 2018-06-14
CA3042004C true CA3042004C (fr) 2025-10-07

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