CA3044877C - Composes de chelate de gadolinium a relaxivite elevee pour utilisation dans l'imagerie par resonance magnetique - Google Patents

Composes de chelate de gadolinium a relaxivite elevee pour utilisation dans l'imagerie par resonance magnetique

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Publication number
CA3044877C
CA3044877C CA3044877A CA3044877A CA3044877C CA 3044877 C CA3044877 C CA 3044877C CA 3044877 A CA3044877 A CA 3044877A CA 3044877 A CA3044877 A CA 3044877A CA 3044877 C CA3044877 C CA 3044877C
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CA
Canada
Prior art keywords
tetraazacyclododecan
carboxylatomethyl
acetyl
tris
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3044877A
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English (en)
Other versions
CA3044877A1 (fr
Inventor
Markus Berger
Jessica Lohrke
Christoph-Stephan Hilger
Gregor Jost
Thomas Frenzel
Olaf Panknin
Hubertus Pietsch
Original Assignee
Bayer Pharma AG
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Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Priority claimed from PCT/EP2017/080306 external-priority patent/WO2018096082A1/fr
Publication of CA3044877A1 publication Critical patent/CA3044877A1/fr
Application granted granted Critical
Publication of CA3044877C publication Critical patent/CA3044877C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Abstract

La présente invention concerne une nouvelle classe de complexes de chélate de gadolinium extracellulaires à relaxivité élevée. L'invention concerne également, des procédés de préparation desdits composés et l'utilisation de ces composés, en tant qu'agents de contraste pour IRM.
CA3044877A 2016-11-28 2017-11-24 Composes de chelate de gadolinium a relaxivite elevee pour utilisation dans l'imagerie par resonance magnetique Active CA3044877C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16200932 2016-11-28
EP16200932.8 2016-11-28
PCT/EP2017/080306 WO2018096082A1 (fr) 2016-11-28 2017-11-24 Composés de chélate de gadolinium à relaxivité élevée pour utilisation dans l'imagerie par résonance magnétique

Publications (2)

Publication Number Publication Date
CA3044877A1 CA3044877A1 (fr) 2018-05-31
CA3044877C true CA3044877C (fr) 2026-03-03

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