CA3049834C - Inhibiteurs selectifs de hdac6, leur methode de preparation et leur application - Google Patents

Inhibiteurs selectifs de hdac6, leur methode de preparation et leur application

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Publication number
CA3049834C
CA3049834C CA3049834A CA3049834A CA3049834C CA 3049834 C CA3049834 C CA 3049834C CA 3049834 A CA3049834 A CA 3049834A CA 3049834 A CA3049834 A CA 3049834A CA 3049834 C CA3049834 C CA 3049834C
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CA
Canada
Prior art keywords
compound
img
pharmaceutically acceptable
group
acceptable salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3049834A
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English (en)
Other versions
CA3049834A1 (fr
Inventor
Hao Wu
Changqing WEI
Qiang Guo
Guifen Zhang
Bin Liu
Yonggang LIAO
Yao Xiao
Shuhui Chen
Original Assignee
CStone Pharmaceuticals Shanghai Co Ltd
CStone Pharmaceuticals Suzhou Co Ltd
CStone Pharmaceuticals
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Application filed by CStone Pharmaceuticals Shanghai Co Ltd, CStone Pharmaceuticals Suzhou Co Ltd, CStone Pharmaceuticals filed Critical CStone Pharmaceuticals Shanghai Co Ltd
Priority claimed from PCT/CN2018/072088 external-priority patent/WO2018130155A1/fr
Publication of CA3049834A1 publication Critical patent/CA3049834A1/fr
Application granted granted Critical
Publication of CA3049834C publication Critical patent/CA3049834C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Abstract

L'invention concerne des composés servant d'inhibiteurs sélectifs de l'histone désacétylase 6 (HDAC6), et leurs applications dans la préparation de médicaments pour le traitement de maladies associées à HDAC6. En particulier, l'invention porte sur un composé représenté par la formule (I) et sur un sel pharmaceutiquement acceptable de celui-ci.
CA3049834A 2017-01-10 2018-01-10 Inhibiteurs selectifs de hdac6, leur methode de preparation et leur application Active CA3049834C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201710017287.2 2017-01-10
CN201710017287 2017-01-10
PCT/CN2018/072088 WO2018130155A1 (fr) 2017-01-10 2018-01-10 Inhibiteurs sélectifs de hdac6, leur méthode de préparation et leur application

Publications (2)

Publication Number Publication Date
CA3049834A1 CA3049834A1 (fr) 2018-07-19
CA3049834C true CA3049834C (fr) 2025-12-09

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