CA3051475A1 - Immunodosage a base de particules magnetiques et ses procedes d'utilisation - Google Patents

Immunodosage a base de particules magnetiques et ses procedes d'utilisation Download PDF

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Publication number
CA3051475A1
CA3051475A1 CA3051475A CA3051475A CA3051475A1 CA 3051475 A1 CA3051475 A1 CA 3051475A1 CA 3051475 A CA3051475 A CA 3051475A CA 3051475 A CA3051475 A CA 3051475A CA 3051475 A1 CA3051475 A1 CA 3051475A1
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Canada
Prior art keywords
reporter
sample
analyte
interest
biomarker
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Pending
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CA3051475A
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English (en)
Inventor
Andrew Ward
Arun Richard Chandrasekaran
Daniel Chen
Christopher Blanchard
Padric GARDEN
Bradley DEMARCO
Joshua Forman
Mounir A. Koussa
Lisa CALDWELL
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Vital Biosciences Inc
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Vital Biosciences Inc
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Application filed by Vital Biosciences Inc filed Critical Vital Biosciences Inc
Publication of CA3051475A1 publication Critical patent/CA3051475A1/fr
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553—Metal or metal coated

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Inorganic Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

L'invention concerne, en partie, des procédés, des dosages et des kits améliorés pour détecter des analytes dans des échantillons biologiques à l'aide de particules magnétiques. Le procédé comprend des étapes de mise en contact d'un échantillon avec un conjugué magnétique constitué d'une particule magnétique et d'un fragment de capture conçu pour se lier à l'analyte d'intérêt dans l'échantillon ; mise en contact de l'échantillon avec un conjugué rapporteur constitué d'un rapporteur et d'un fragment se liant au rapporteur conçu pour se lier à l'analyte d'intérêt dans l'échantillon ; liaison de l'analyte d'intérêt avec le fragment de capture et le fragment se liant au rapporteur ; séparation de l'analyte d'intérêt de l'échantillon par application d'un champ magnétique à la chambre d'analyse ; et détection de la présence, de l'absence ou du niveau de l'analyte d'intérêt par détection du rapporteur.
CA3051475A 2017-01-26 2018-01-26 Immunodosage a base de particules magnetiques et ses procedes d'utilisation Pending CA3051475A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762450623P 2017-01-26 2017-01-26
US62/450,623 2017-01-26
US201762544393P 2017-08-11 2017-08-11
US62/544,393 2017-08-11
PCT/US2018/015440 WO2018140719A1 (fr) 2017-01-26 2018-01-26 Immunodosage à base de particules magnétiques et ses procédés d'utilisation

Publications (1)

Publication Number Publication Date
CA3051475A1 true CA3051475A1 (fr) 2018-08-02

Family

ID=62978769

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3051475A Pending CA3051475A1 (fr) 2017-01-26 2018-01-26 Immunodosage a base de particules magnetiques et ses procedes d'utilisation

Country Status (4)

Country Link
EP (1) EP3574309A4 (fr)
CN (1) CN110462383A (fr)
CA (1) CA3051475A1 (fr)
WO (1) WO2018140719A1 (fr)

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CN114739986A (zh) * 2022-04-22 2022-07-12 东南大学 TiO2纳米花负载CdTe量子点的电化学发光免疫传感器及其制备方法和应用
CN116134151A (zh) * 2020-08-07 2023-05-16 维塔生物科技公司 多重分析物检测
EP4193148A4 (fr) * 2020-08-07 2024-11-06 Vital Biosciences Inc. Modulation cinétique pour la détection d'analyte magnétique

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CN112823048A (zh) * 2018-07-27 2021-05-18 维拉维斯公司 消除和富集的方法
KR102138192B1 (ko) * 2018-12-28 2020-07-27 (주)프로테옴텍 다수 개의 검사선을 구비한 임신진단용 면역크로마토그래피 스트립 및 이를 포함하는 임신진단키트
US12007388B2 (en) * 2019-08-22 2024-06-11 The Hong Kong University Of Science And Technology System for single-molecule isolation for cell populations and single cells, and methods and uses thereof
CN110618265B (zh) * 2019-09-12 2023-04-18 广东省药品检验所（广东省药品质量研究所、广东省口岸药品检验所） 一种沙丁胺醇的可视化检测方法
CN111024938B (zh) * 2019-11-27 2023-05-26 武汉市农业科学院 一种病原微生物快速检测方法
GB202006800D0 (en) * 2020-05-07 2020-06-24 Cambridge Entpr Ltd Carrier system and method
GB202019024D0 (en) * 2020-12-02 2021-01-13 Paraytec Ltd Diagnostic testing
CN112710858A (zh) * 2020-12-15 2021-04-27 深圳天辰医疗科技有限公司 试剂盒及其制备方法和应用
CN112526121B (zh) * 2020-12-18 2022-11-18 深圳普门科技股份有限公司 血清淀粉样蛋白a检测试剂盒及其检测系统
CN112748096B (zh) * 2020-12-29 2022-03-18 山西大学 一种磺胺二甲氧嘧啶的室温磷光检测方法及应用
CN112763484B (zh) * 2021-01-27 2022-05-03 南京医科大学 一种基于比色生物传感器检测谷胱甘肽和/或过氧化氢的方法
CN113373156A (zh) * 2021-06-30 2021-09-10 四川携光生物技术有限公司 自身免疫性脑炎相关的nmdar重组蛋白、其编码序列、制法和应用
CN114152741B (zh) * 2021-11-18 2022-08-19 上海北昂医药科技股份有限公司 一种提高有效微珠比例的dELISA样品及其制备与检测方法
CN113960313B (zh) * 2021-12-22 2022-04-12 上海思路迪医学检验所有限公司 一种外泌体alk融合蛋白磁免疫化学发光检测试剂盒
CN114706023A (zh) * 2022-06-06 2022-07-05 中国科学技术大学 生物分子相互作用的磁学检测方法
WO2024102748A1 (fr) * 2022-11-07 2024-05-16 Kephera Diagnostics, Llc Méthodes, instruments de diagnostic et kits de détection de maladies
CN115815588B (zh) * 2022-11-30 2024-06-28 山东省淡水渔业研究院（山东省淡水渔业监测中心） 基于纳米钯/多层空心球状Pd/CuO@NiO检测水产品中孔雀石绿的方法
WO2024175169A1 (fr) * 2023-02-20 2024-08-29 STILLER, Olaf Procédé permettant de détecter directement la présence d'une substance de test
CN116392591B (zh) * 2023-04-06 2025-08-08 暨南大学 基于硒化钼的磁性纳米捕捉系统制备方法和应用
CN118441163B (zh) * 2024-04-16 2025-12-19 江西理工大学 一种从废旧钕铁硼磁体中回收镓的方法
CN119375196A (zh) * 2024-10-29 2025-01-28 福建省妇幼保健院 一种基于核壳结构上转换纳米粒子检测microRNA的方法
CN120009554A (zh) * 2025-04-21 2025-05-16 天津市肿瘤医院（天津医科大学肿瘤医院） 一种用于ProGRP检测的免疫平台及制备方法和应用
CN121276065B (zh) * 2025-12-02 2026-03-31 湖北大学 一种基于尿液合成dna检测aki的生物传感器及应用

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116134151A (zh) * 2020-08-07 2023-05-16 维塔生物科技公司 多重分析物检测
EP4193147A4 (fr) * 2020-08-07 2024-10-23 Vital Biosciences Inc. Détection d'analyte multiplexée
EP4193148A4 (fr) * 2020-08-07 2024-11-06 Vital Biosciences Inc. Modulation cinétique pour la détection d'analyte magnétique
CN114739986A (zh) * 2022-04-22 2022-07-12 东南大学 TiO2纳米花负载CdTe量子点的电化学发光免疫传感器及其制备方法和应用
CN114739986B (zh) * 2022-04-22 2025-03-21 东南大学 TiO2纳米花负载CdTe量子点的电化学发光免疫传感器及其制备方法和应用

Also Published As

Publication number Publication date
EP3574309A1 (fr) 2019-12-04
EP3574309A4 (fr) 2020-11-11
CN110462383A (zh) 2019-11-15
WO2018140719A1 (fr) 2018-08-02

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