CA3058486C - Acides nucleiques p-ethoxy destines a inhiber bcl2 - Google Patents

Acides nucleiques p-ethoxy destines a inhiber bcl2

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Publication number
CA3058486C
CA3058486C CA3058486A CA3058486A CA3058486C CA 3058486 C CA3058486 C CA 3058486C CA 3058486 A CA3058486 A CA 3058486A CA 3058486 A CA3058486 A CA 3058486A CA 3058486 C CA3058486 C CA 3058486C
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CA
Canada
Prior art keywords
composition
oligonucleotides
cancer
population
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3058486A
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English (en)
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CA3058486A1 (fr
Inventor
Ana Tari ASHIZAWA
Peter Nielsen
Original Assignee
Bio Path Holdings Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Bio Path Holdings Inc filed Critical Bio Path Holdings Inc
Priority claimed from PCT/US2018/028267 external-priority patent/WO2018195253A1/fr
Publication of CA3058486A1 publication Critical patent/CA3058486A1/fr
Application granted granted Critical
Publication of CA3058486C publication Critical patent/CA3058486C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Abstract

L'invention concerne des systèmes d'administration améliorés pour oligonucléotides, ledit système d'administration comprenant un liposome contenant des phospholipides neutres et un oligonucléotide P-éthoxy qui cible un polynucléotide codant BCL2. L'invention concerne également des méthodes de traitement de patients au moyen desdits systèmes d'administration.
CA3058486A 2017-04-19 2018-04-19 Acides nucleiques p-ethoxy destines a inhiber bcl2 Active CA3058486C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762487302P 2017-04-19 2017-04-19
US62/487,302 2017-04-19
PCT/US2018/028267 WO2018195253A1 (fr) 2017-04-19 2018-04-19 Acides nucléiques p-éthoxy destinés à inhiber bcl2

Publications (2)

Publication Number Publication Date
CA3058486A1 CA3058486A1 (fr) 2018-10-25
CA3058486C true CA3058486C (fr) 2025-07-22

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