CA3059773C - Composes et methodes de traitement d'infections bacteriennes - Google Patents

Composes et methodes de traitement d'infections bacteriennes

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Publication number
CA3059773C
CA3059773C CA3059773A CA3059773A CA3059773C CA 3059773 C CA3059773 C CA 3059773C CA 3059773 A CA3059773 A CA 3059773A CA 3059773 A CA3059773 A CA 3059773A CA 3059773 C CA3059773 C CA 3059773C
Authority
CA
Canada
Prior art keywords
alkyl
mmol
int
oxo
methanopyrazolo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3059773A
Other languages
English (en)
Other versions
CA3059773A1 (fr
Inventor
Janelle Comita-Prevoir
Thomas Francois Durand-Reville
Satenig Guler
Jan Romero
Mark Sylvester
Ruben Tommasi
Camilo Velez-Vega
Xiaoyun Wu
Jing Zhang
Original Assignee
Entasis Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Entasis Therapeutics Inc filed Critical Entasis Therapeutics Inc
Priority claimed from PCT/US2018/031593 external-priority patent/WO2018208769A1/fr
Publication of CA3059773A1 publication Critical patent/CA3059773A1/fr
Application granted granted Critical
Publication of CA3059773C publication Critical patent/CA3059773C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Abstract

La présente invention concerne des composés représentés par la formule (I) ou un sel pharmaceutiquement acceptable de ceux-ci. Dans cette formule, X, Y, R4, R5, et R6 sont tels que définis dans la description. La présente invention concerne également des compositions pharmaceutiques comprenant les composés de formule (I).
CA3059773A 2017-05-08 2018-05-08 Composes et methodes de traitement d'infections bacteriennes Active CA3059773C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762502867P 2017-05-08 2017-05-08
US62/502,867 2017-05-08
PCT/US2018/031593 WO2018208769A1 (fr) 2017-05-08 2018-05-08 Composés et méthodes de traitement d'infections bactériennes

Publications (2)

Publication Number Publication Date
CA3059773A1 CA3059773A1 (fr) 2018-11-15
CA3059773C true CA3059773C (fr) 2025-09-16

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