CA3063889C - Therapie electromagnetique pulsee et par ultrasons pour stimuler des proteines de choc thermique ciblees et faciliter une reparation de proteine - Google Patents

Therapie electromagnetique pulsee et par ultrasons pour stimuler des proteines de choc thermique ciblees et faciliter une reparation de proteine Download PDF

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Publication number
CA3063889C
CA3063889C CA3063889A CA3063889A CA3063889C CA 3063889 C CA3063889 C CA 3063889C CA 3063889 A CA3063889 A CA 3063889A CA 3063889 A CA3063889 A CA 3063889A CA 3063889 C CA3063889 C CA 3063889C
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Prior art keywords
tissue
para
laser light
laser
heat shock
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CA3063889A1 (fr
Inventor
Jeffrey K. LUTTRULL
Benjamin W. L. Margolis
David B. Chang
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Ojai Retinal Technology LLC
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Ojai Retinal Technology LLC
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Priority claimed from US14/607,959 external-priority patent/US9168174B2/en
Priority claimed from US14/922,885 external-priority patent/US9427602B2/en
Application filed by Ojai Retinal Technology LLC filed Critical Ojai Retinal Technology LLC
Publication of CA3063889A1 publication Critical patent/CA3063889A1/fr
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/0625Warming the body, e.g. hyperthermia treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/067Radiation therapy using light using laser light
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B18/1492Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B2018/2065Multiwave; Wavelength mixing, e.g. using four or more wavelengths
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/063Radiation therapy using light comprising light transmitting means, e.g. optical fibres
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0635Radiation therapy using light characterised by the body area to be irradiated
    • A61N2005/0642Irradiating part of the body at a certain distance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0658Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0661Radiation therapy using light characterised by the wavelength of light used ultraviolet
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N2007/0043Ultrasound therapy intra-cavitary
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0601Apparatus for use inside the body
    • A61N5/0603Apparatus for use inside the body for treatment of body cavities

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Diabetes (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Laser Surgery Devices (AREA)
  • Radiation-Therapy Devices (AREA)
  • Surgical Instruments (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Il est décrit un système et un procédé pour stimuler lactivation de protéines de choc thermique et faciliter une réparation de protéine dans des cellules et des tissus de façon à tirer profit de la nature de correction et de restauration de lactivation ou production de protéine de choc thermique accrue et de la facilitation de réparation de protéine, tout en nendommageant pas les cellules et tissus. Ce procédé consiste à traiter une zone cible spécifiée avec une source de rayonnement ultrasonore ou électromagnétique qui est pulsée et appliquée ou concentrée sur au moins une petite zone de façon à obtenir laugmentation de température nécessaire ou contraindre suffisamment les cellules et tissus pour stimuler la production ou activation de protéine de choc thermiques et faciliter une réparation de protéine, tout en permettant à la température de diminuer suffisamment rapidement pour ne pas endommager ou détruire le tissu traité.
CA3063889A 2015-01-28 2015-11-16 Therapie electromagnetique pulsee et par ultrasons pour stimuler des proteines de choc thermique ciblees et faciliter une reparation de proteine Active CA3063889C (fr)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US14/607,959 US9168174B2 (en) 2012-05-25 2015-01-28 Process for restoring responsiveness to medication in tissue of living organisms
US14/607,959 2015-01-28
US201562153616P 2015-04-28 2015-04-28
US62/153,616 2015-04-28
US14/922,885 2015-10-26
US14/922,885 US9427602B2 (en) 2012-05-25 2015-10-26 Pulsating electromagnetic and ultrasound therapy for stimulating targeted heat shock proteins and facilitating protein repair
CA2972416A CA2972416C (fr) 2015-01-28 2015-11-16 Therapie electromagnetique pulsee et par ultrasons pour stimuler des proteines de choc thermique ciblees et faciliter une reparation de proteine

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA2972416A Division CA2972416C (fr) 2015-01-28 2015-11-16 Therapie electromagnetique pulsee et par ultrasons pour stimuler des proteines de choc thermique ciblees et faciliter une reparation de proteine

Publications (2)

Publication Number Publication Date
CA3063889A1 CA3063889A1 (fr) 2016-08-04
CA3063889C true CA3063889C (fr) 2023-03-14

Family

ID=56544130

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2972416A Active CA2972416C (fr) 2015-01-28 2015-11-16 Therapie electromagnetique pulsee et par ultrasons pour stimuler des proteines de choc thermique ciblees et faciliter une reparation de proteine
CA3063889A Active CA3063889C (fr) 2015-01-28 2015-11-16 Therapie electromagnetique pulsee et par ultrasons pour stimuler des proteines de choc thermique ciblees et faciliter une reparation de proteine

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CA2972416A Active CA2972416C (fr) 2015-01-28 2015-11-16 Therapie electromagnetique pulsee et par ultrasons pour stimuler des proteines de choc thermique ciblees et faciliter une reparation de proteine

Country Status (8)

Country Link
EP (1) EP3250139A4 (fr)
JP (2) JP6480588B2 (fr)
CN (1) CN107205768B (fr)
AU (1) AU2015380411B2 (fr)
BR (1) BR112017016288A2 (fr)
CA (2) CA2972416C (fr)
SG (1) SG11201705677WA (fr)
WO (1) WO2016122752A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3030483A1 (fr) * 2016-08-09 2018-02-15 Ojai Retinal Technology, Llc Processus destine a fournir une therapie protectrice pour des tissus ou de fluides biologiques
CN110582238A (zh) * 2017-05-01 2019-12-17 奥哈伊视网膜技术有限责任公司 用于治疗近视的系统及方法
CN111343936B (zh) * 2017-11-15 2024-03-22 奥哈伊视网膜技术有限责任公司 利用能量治疗生物组织的方法及系统
JP2021521955A (ja) * 2018-04-24 2021-08-30 セントレ ナショナル デ ラ リシェルシェ サイエンティフィック(セ・エン・エル・エス) マイクロ波誘導型熱プロファイルを使用して生体組織及び細胞に影響を与えるための発生装置及び方法
CN110681059A (zh) * 2019-09-28 2020-01-14 复旦大学 一种颈椎病光疗设备
CN112494135A (zh) * 2020-11-20 2021-03-16 毕勇 一种支气管哮喘的激光热成形治疗装置

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5348002A (en) * 1992-04-23 1994-09-20 Sirraya, Inc. Method and apparatus for material analysis
WO2000023147A1 (fr) * 1998-10-20 2000-04-27 Dornier Medtech Holding International Gmbh Therapie thermique assortie d'une protection des tissus
JP2001104334A (ja) * 1999-10-08 2001-04-17 Olympus Optical Co Ltd 医療用システム
GB0422525D0 (en) * 2004-10-11 2004-11-10 Luebcke Peter Dermatological compositions and methods
JP2008109954A (ja) * 2006-10-27 2008-05-15 Matsushita Electric Works Ltd カプセル型撮像装置
EP2207595A4 (fr) * 2007-10-19 2012-10-24 Lockheed Corp Système et procédé de conditionnement de tissu animal par rayon laser
CA2706563C (fr) * 2007-11-21 2018-08-21 Focus Surgery, Inc. Methode de diagnostic et de traitement de tumeurs par ultrasons focalises a haute intensite
US8141557B2 (en) * 2008-10-22 2012-03-27 Peyman Gholam A Method of oscillatory thermotherapy of biological tissue
US10219947B2 (en) * 2012-05-25 2019-03-05 Ojai Retinal Technology, Llc System and process for retina phototherapy
KR102036646B1 (ko) * 2012-09-10 2019-10-25 더말 포토닉스 코포레이션 피부과 결함들을 치료하기 위한 시스템들 및 방법들
US9333371B2 (en) * 2012-11-01 2016-05-10 Seminex Corporation Variable intensity laser treatments of the skin

Also Published As

Publication number Publication date
EP3250139A4 (fr) 2018-06-27
JP2018503434A (ja) 2018-02-08
JP2019108334A (ja) 2019-07-04
EP3250139A1 (fr) 2017-12-06
CA2972416C (fr) 2020-01-14
SG11201705677WA (en) 2017-08-30
BR112017016288A2 (pt) 2018-03-27
JP6778772B2 (ja) 2020-11-04
CA2972416A1 (fr) 2016-08-04
CA3063889A1 (fr) 2016-08-04
AU2015380411A1 (en) 2017-07-20
WO2016122752A1 (fr) 2016-08-04
CN107205768A (zh) 2017-09-26
JP6480588B2 (ja) 2019-03-13
AU2015380411B2 (en) 2019-03-14
CN107205768B (zh) 2020-06-16

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