CA3066953A1 - Anticorps monoclonaux humains specifiques de cd33 et leurs procedes d'utilisation - Google Patents

Anticorps monoclonaux humains specifiques de cd33 et leurs procedes d'utilisation Download PDF

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Publication number
CA3066953A1
CA3066953A1 CA3066953A CA3066953A CA3066953A1 CA 3066953 A1 CA3066953 A1 CA 3066953A1 CA 3066953 A CA3066953 A CA 3066953A CA 3066953 A CA3066953 A CA 3066953A CA 3066953 A1 CA3066953 A1 CA 3066953A1
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CA
Canada
Prior art keywords
seq
antibody
antigen
domain
binding fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA3066953A
Other languages
English (en)
Inventor
Dimiter S. Dimitrov
Weizao Chen
Zhongyu Zhu
Rimas J. ORENTAS
Boro Dropulic
Dina SCHNEIDER
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lentigen Technology Inc
US Department of Health and Human Services
Original Assignee
Lentigen Technology Inc
US Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lentigen Technology Inc, US Department of Health and Human Services filed Critical Lentigen Technology Inc
Publication of CA3066953A1 publication Critical patent/CA3066953A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

L'invention concerne des anticorps monoclonaux humains qui se lient spécifiquement à CD33. L'invention concerne également des conjugués d'anticorps qui comprennent les anticorps monoclonaux spécifiques de CD33 (ou des fragments de liaison à l'antigène). L'invention concerne en outre des procédés de détection, de diagnostic et de traitement du cancer positif à CD33.
CA3066953A 2017-06-30 2018-06-29 Anticorps monoclonaux humains specifiques de cd33 et leurs procedes d'utilisation Abandoned CA3066953A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762527165P 2017-06-30 2017-06-30
US62/527,165 2017-06-30
PCT/US2018/040257 WO2019006280A1 (fr) 2017-06-30 2018-06-29 Anticorps monoclonaux humains spécifiques de cd33 et leurs procédés d'utilisation

Publications (1)

Publication Number Publication Date
CA3066953A1 true CA3066953A1 (fr) 2019-01-03

Family

ID=62976328

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3066953A Abandoned CA3066953A1 (fr) 2017-06-30 2018-06-29 Anticorps monoclonaux humains specifiques de cd33 et leurs procedes d'utilisation

Country Status (2)

Country Link
CA (1) CA3066953A1 (fr)
WO (1) WO2019006280A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2021013416A (es) 2019-05-04 2021-12-10 Inhibrx Inc Polipeptidos de union al antigeno cd33 y sus usos.
CN116368154A (zh) 2020-10-08 2023-06-30 阿菲姆德股份有限公司 三特异性结合剂
AU2022320948A1 (en) 2021-07-30 2024-01-18 Affimed Gmbh Duplexbodies
JP2024543822A (ja) 2021-11-03 2024-11-26 アフィメド ゲーエムベーハー 二重特異性ｃｄ１６ａバインダー
US20240173425A1 (en) * 2022-06-22 2024-05-30 Eli Lilly And Company Human cd33 antibodies and glucocorticoid conjugates
WO2024196877A1 (fr) * 2023-03-22 2024-09-26 University Of Florida Research Foundation, Incorporated Anticorps monoclonaux de lapin ciblant des antigènes de leucémie myéloïde aiguë
WO2025202213A1 (fr) 2024-03-26 2025-10-02 Institut National de la Santé et de la Recherche Médicale Nanoparticule lipidique chargée d'agent antitumoral et fonctionnalisée pour cibler des cellules immosuppressives
WO2026055461A1 (fr) * 2024-09-05 2026-03-12 Aperture Therapeutics, Inc. Conjugués anticorps-oligonucléotide comprenant un agent polynucléotidique antisens conjugué à un anticorps cd33, et leurs procédés d'utilisation
CN121673409A (zh) * 2024-09-12 2026-03-17 安诺柏德生物医药科技(苏州)有限公司 靶向人cd33的人源化抗体及其应用

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20220301