CA3068444C - Recepteurs antigeniques chimeriques vers l'antigene de maturation des lymphocytes b presentant des domaines humains - Google Patents

Recepteurs antigeniques chimeriques vers l'antigene de maturation des lymphocytes b presentant des domaines humains

Info

Publication number
CA3068444C
CA3068444C CA3068444A CA3068444A CA3068444C CA 3068444 C CA3068444 C CA 3068444C CA 3068444 A CA3068444 A CA 3068444A CA 3068444 A CA3068444 A CA 3068444A CA 3068444 C CA3068444 C CA 3068444C
Authority
CA
Canada
Prior art keywords
car
cells
cell
seq
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3068444A
Other languages
English (en)
Other versions
CA3068444A1 (fr
Inventor
James N. KOCHENDERFER
Norris Lam
Nathan Trinklein
Katherine E. Harris
Shelley Force Aldred
Wim van Schooten
Original Assignee
TeneoBio Inc
US Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TeneoBio Inc, US Department of Health and Human Services filed Critical TeneoBio Inc
Priority claimed from PCT/US2018/039917 external-priority patent/WO2019006072A1/fr
Publication of CA3068444A1 publication Critical patent/CA3068444A1/fr
Application granted granted Critical
Publication of CA3068444C publication Critical patent/CA3068444C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Abstract

L'invention concerne des récepteurs antigéniques chimériques (CAR) ayant une spécificité antigénique pour l'antigène de maturation des lymphocytes B (BCMA). L'invention concerne également des acides nucléiques, des vecteurs d'expression recombinants, des cellules hôtes, des populations de cellules, et des compositions pharmaceutiques se rapportant aux CAR. L'invention concerne en outre des méthodes de traitement et de prévention du cancer chez un mammifère.
CA3068444A 2017-06-30 2018-06-28 Recepteurs antigeniques chimeriques vers l'antigene de maturation des lymphocytes b presentant des domaines humains Active CA3068444C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762527556P 2017-06-30 2017-06-30
US62/527,556 2017-06-30
PCT/US2018/039917 WO2019006072A1 (fr) 2017-06-30 2018-06-28 Récepteurs antigéniques chimériques vers l'antigène de maturation des lymphocytes b présentant des domaines humains

Publications (2)

Publication Number Publication Date
CA3068444A1 CA3068444A1 (fr) 2019-01-03
CA3068444C true CA3068444C (fr) 2025-09-16

Family

ID=

Similar Documents

Publication Publication Date Title
US12570717B2 (en) Anti-B-cell maturation antigen chimeric antigen receptors with human domains
AU2016338747B2 (en) Anti-CD30 chimeric antigen receptors
US20210363245A1 (en) Bicistronic chimeric antigen receptors targeting cd19 and cd20 and their uses
US11951131B2 (en) Anti-SLAMF7 chimeric antigen receptors
AU2022241765A1 (en) Bicistronic chimeric antigen receptors designed to reduce retroviral recombination and uses thereof
CA3068444C (fr) Recepteurs antigeniques chimeriques vers l'antigene de maturation des lymphocytes b presentant des domaines humains
HK40090152A (en) Anti-b-cell maturation antigen chimeric antigen receptors with human domains
HK40030302A (en) Anti-b-cell maturation antigen chimeric antigen receptors with human domains
HK40030302B (en) Anti-b-cell maturation antigen chimeric antigen receptors with human domains