CA3090917C - Tcr nyeso - Google Patents

Tcr nyeso

Info

Publication number
CA3090917C
CA3090917C CA3090917A CA3090917A CA3090917C CA 3090917 C CA3090917 C CA 3090917C CA 3090917 A CA3090917 A CA 3090917A CA 3090917 A CA3090917 A CA 3090917A CA 3090917 C CA3090917 C CA 3090917C
Authority
CA
Canada
Prior art keywords
tcr
seq
cells
amino acid
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3090917A
Other languages
English (en)
Other versions
CA3090917A1 (fr
Inventor
Carina WEHNER
Manon WEIS
Original Assignee
Medigene Immunotherapies GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medigene Immunotherapies GmbH filed Critical Medigene Immunotherapies GmbH
Priority claimed from PCT/EP2019/051963 external-priority patent/WO2019162043A1/fr
Publication of CA3090917A1 publication Critical patent/CA3090917A1/fr
Application granted granted Critical
Publication of CA3090917C publication Critical patent/CA3090917C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Abstract

La présente invention concerne un récepteur de lymphocytes T (TCR) isolé spécifique pour NY- ESO-1/LAGE-1 et un polypeptide comprenant une fraction fonctionnelle du TCR. L'invention concerne en outre un complexe TCR multivalent, un acide nucléique codant pour un TCR, une cellule exprimant le TCR et une composition pharmaceutique comprenant le TCR. L'invention concerne également un TCR destiné à être utilisé comme médicament, en particulier un TCR pour une utilisation dans le traitement du cancer.
CA3090917A 2018-02-26 2019-01-28 Tcr nyeso Active CA3090917C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
LULU100715 2018-02-26
LU100715 2018-02-26
PCT/EP2019/051963 WO2019162043A1 (fr) 2018-02-26 2019-01-28 Tcr nyeso

Publications (2)

Publication Number Publication Date
CA3090917A1 CA3090917A1 (fr) 2019-08-29
CA3090917C true CA3090917C (fr) 2025-11-25

Family

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