CA3110905C - Recepteurs d'antigenes chimeriques contre de multiples isoformes de hla-g - Google Patents

Recepteurs d'antigenes chimeriques contre de multiples isoformes de hla-g

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Publication number
CA3110905C
CA3110905C CA3110905A CA3110905A CA3110905C CA 3110905 C CA3110905 C CA 3110905C CA 3110905 A CA3110905 A CA 3110905A CA 3110905 A CA3110905 A CA 3110905A CA 3110905 C CA3110905 C CA 3110905C
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CA
Canada
Prior art keywords
hla
car
cells
domain
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3110905A
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English (en)
Other versions
CA3110905A1 (fr
Inventor
Maria LOUSTAU
Francois ANNA
Pierre Langlade Demoyen
Julien CAUMARTIN
Original Assignee
Invectys SAS
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Application filed by Invectys SAS filed Critical Invectys SAS
Priority claimed from PCT/EP2019/073257 external-priority patent/WO2020043899A1/fr
Publication of CA3110905A1 publication Critical patent/CA3110905A1/fr
Application granted granted Critical
Publication of CA3110905C publication Critical patent/CA3110905C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Abstract

La présente invention concerne des récepteurs d'antigènes chimériques (CAR) contre de multiples mais pas toutes les isoformes de l'antigène des leucocytes humains (HLA-G). Plus spécifiquement, l'invention concerne des CAR qui sont spécifiques à des isoformes immunosuppressives associées à HLA-G ß2M ou HLA-G sans ß2M respectivement.
CA3110905A 2018-08-31 2019-08-30 Recepteurs d'antigenes chimeriques contre de multiples isoformes de hla-g Active CA3110905C (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP18306153.0 2018-08-31
EP18306153 2018-08-31
EP19305809.6 2019-06-21
EP19305809 2019-06-21
PCT/EP2019/073257 WO2020043899A1 (fr) 2018-08-31 2019-08-30 Récepteurs d'antigènes chimériques contre de multiples isoformes de hla-g

Publications (2)

Publication Number Publication Date
CA3110905A1 CA3110905A1 (fr) 2020-03-05
CA3110905C true CA3110905C (fr) 2025-11-25

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