CA3120740C - Anticorps humanise anti-recepteur de l'igf-i - Google Patents

Anticorps humanise anti-recepteur de l'igf-i

Info

Publication number
CA3120740C
CA3120740C CA3120740A CA3120740A CA3120740C CA 3120740 C CA3120740 C CA 3120740C CA 3120740 A CA3120740 A CA 3120740A CA 3120740 A CA3120740 A CA 3120740A CA 3120740 C CA3120740 C CA 3120740C
Authority
CA
Canada
Prior art keywords
igf
amino acid
antibody
receptor
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3120740A
Other languages
English (en)
Other versions
CA3120740A1 (fr
Inventor
Akira Tanokura
Hirotsugu Kato
Hiroshi Eguchi
Kenichiro Takagi
Satoshi Yamamura
Naoko Namiki
Daisuke Ishikawa
Hirofumi Higuchi
Tomoyo TAKEO
Masayo OHORI
Original Assignee
Teijin Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Pharma Ltd filed Critical Teijin Pharma Ltd
Priority claimed from PCT/JP2019/047050 external-priority patent/WO2020116398A1/fr
Publication of CA3120740A1 publication Critical patent/CA3120740A1/fr
Application granted granted Critical
Publication of CA3120740C publication Critical patent/CA3120740C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Abstract

L'invention concerne un anticorps humanisé qui, par l'intermédiaire du récepteur de l'IGF-I, augmente la masse musculaire mais ne diminue pas le taux de glycémie. Cet anticorps humanisé : est un anticorps humanisé anti-récepteur de l'IGF-I, un fragment de celui-ci ou un dérivé de celui-ci; a une séquence d'acides aminés spécifique telle que les SEQ ID No. : 1 à 6 servant de séquence de CDR; et se lie spécifiquement au domaine extracellulaire du récepteur de l'IGF-I.
CA3120740A 2018-12-03 2019-12-02 Anticorps humanise anti-recepteur de l'igf-i Active CA3120740C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2018-226669 2018-12-03
JP2018226669 2018-12-03
PCT/JP2019/047050 WO2020116398A1 (fr) 2018-12-03 2019-12-02 Anticorps humanisé anti-récepteur de l'igf-i

Publications (2)

Publication Number Publication Date
CA3120740A1 CA3120740A1 (fr) 2020-06-11
CA3120740C true CA3120740C (fr) 2025-09-16

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