CA3124023C - Nucleotides proteges en 3' - Google Patents

Nucleotides proteges en 3'

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Publication number
CA3124023C
CA3124023C CA3124023A CA3124023A CA3124023C CA 3124023 C CA3124023 C CA 3124023C CA 3124023 A CA3124023 A CA 3124023A CA 3124023 A CA3124023 A CA 3124023A CA 3124023 C CA3124023 C CA 3124023C
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CA
Canada
Prior art keywords
group
nucleotide
independently
substituted
bond
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3124023A
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English (en)
Other versions
CA3124023A1 (fr
Inventor
Frank Bergmann
Peter Crisalli
Dieter Heindl
Omid Khakshoor
Meng Taing
Original Assignee
F Hoffmann La Roche AG
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Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Priority claimed from PCT/US2019/066670 external-priority patent/WO2020131759A1/fr
Publication of CA3124023A1 publication Critical patent/CA3124023A1/fr
Application granted granted Critical
Publication of CA3124023C publication Critical patent/CA3124023C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Abstract

Il est décrit un nucléotide ou un sel connexe de formule (IHA) : X est une nucléobase ou une nucléobase marquée; et Y est un -O-P(O)(OH)-[O-P(O)(OH)]ZOH ou un -O-P(O)(OH)-[O-P(O)(OH)]z-O-oligonucléotide, z étant 0 ou un nombre entier de 1 à 5. Des systèmes et des méthodes de séquençage utilisant le nucléotide ou le sel sont aussi décrits.
CA3124023A 2018-12-19 2019-12-16 Nucleotides proteges en 3' Active CA3124023C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862781638P 2018-12-19 2018-12-19
US62/781,638 2018-12-19
PCT/US2019/066670 WO2020131759A1 (fr) 2018-12-19 2019-12-16 Nucléotides protégés en 3'

Publications (2)

Publication Number Publication Date
CA3124023A1 CA3124023A1 (fr) 2020-06-25
CA3124023C true CA3124023C (fr) 2025-08-12

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